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Protein
Submitted name:

Centrosomal protein of 192 kDa

Gene

CEP192

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Centrosomal protein of 192 kDaImported
Gene namesi
Name:CEP192Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 18

Organism-specific databases

EuPathDBiHostDB:ENSG00000101639.18
HGNCiHGNC:25515 CEP192

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000101639

PTM / Processingi

Proteomic databases

EPDiA0A0A0MR42
MaxQBiA0A0A0MR42
PeptideAtlasiA0A0A0MR42
PRIDEiA0A0A0MR42

Expressioni

Gene expression databases

BgeeiENSG00000101639 Expressed in 203 organ(s), highest expression level in heart
ExpressionAtlasiA0A0A0MR42 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A0A0MR42
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IG8G Eukaryota
ENOG4110RMB LUCA
GeneTreeiENSGT00510000048187

Family and domain databases

Gene3Di2.60.40.10, 3 hits
InterProiView protein in InterPro
IPR013783 Ig-like_fold
IPR039103 Spd-2/CEP192
PANTHERiPTHR16029 PTHR16029, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.Show allAlign All

A0A0A0MR42-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDGCLDTETP TVSIQENVDV ASLKPISDSG INFTDAIWSP TCERRTCECH
60 70 80 90 100
ESIEKNKDKT DLPQSVVYQN EEGRWVTDLA YYTSFNSKQN LNVSLSDEMN
110 120 130 140 150
EDFRSGSEAF DLIAQDEEEF NKEHQFIQPS FGYFIRSPEK REPIALIRKS
160 170 180 190 200
DVSRGNLEKE MAHLNHDLYS GDLNEQSQAQ LSEGSITLQV EAVESTSQVD
210 220 230 240 250
ENDVTLTADK GKTEDTFFMS NKPQRYKDKL PDSGDSMLRI STIASAIAEA
260 270 280 290 300
SVNTDPSQLA AMIKALSNKT RDKTFQEDEK QKDYSHVRHF LPNDLEKSNG
310 320 330 340 350
SNALDMEKYL KKTEVSRYES ALENFSRASM SDTWDLSLPK EQTTQDIHPV
360 370 380 390 400
DLSATSVSVR APEENTAAIV YVENGESENQ ESFRTINSSN SVTNRENNSA
410 420 430 440 450
VVDVKTCSID NKLQDVGNDE KATSISTPSD SYSSVRNPRI TSLCLLKDCE
460 470 480 490 500
EIRDNRENQR QNECVSEISN SEKHVTFENH RIVSPKNSDL KNTSPEHGGR
510 520 530 540 550
GSEDEQESFR PSTSPLSHSS PSEISGTSSS GCALESFGSA AQQQQPPCEQ
560 570 580 590 600
ELSPLVCSPA GVSRLTYVSE PESSYPTTAT DDALEDRKSD ITSELSTTII
610 620 630 640 650
QGSPAALEER AMEKLREKVP FQNRGKGTLS SIIQNNSDTR KATETTSLSS
660 670 680 690 700
KPEYVKPDFR WSKDPSSKSG NLLETSEVGW TSNPEELDPI RLALLGKSGL
710 720 730 740 750
SCQVGSATSH PVSCQEPIDE DQRISPKDKS TAGREFSGQV SHQTTSENQC
760 770 780 790 800
TPIPSSTVHS SVADMQNMPA AVHALLTQPS LSAAPFAQRY LGTLPSTGST
810 820 830 840 850
TLPQCHAGNA TVCGFSGGLP YPAVAGEPVQ NSVAVGICLG SNIGSGWMGT
860 870 880 890 900
SSLCNPYSNT LNQNLLSTTK PFPVPSVGTN CGIEPWDSGV TSGLGSVRVP
910 920 930 940 950
EELKLPHACC VGIASQTLLS VLNPTDRWLQ VSIGVLSISV NGEKVDLSTY
960 970 980 990 1000
RCLVFKNKAI IRPHATEEIK VLFIPSSPGV FRCTFSVASW PCSTDAETIV
1010 1020 1030 1040 1050
QAEALASTVT LTAIAESPVI EVETEKKDVL DFGDLTYGGW KALPLKLINR
1060 1070 1080 1090 1100
THATVPIRLI INANAVAWRC FTFSKESVRA PVEVAPCADV VTRLAGPSVV
1110 1120 1130 1140 1150
NHMMPASYDG QDPEFLMIWV LFHSPKKQIS SSDILDSAEE FSAKVDIEVD
1160 1170 1180 1190 1200
SPNPTPVLRS VSLRARAGIA RIHAPRDLQT MHFLAKVASS RKQHLPLKNA
1210 1220 1230 1240 1250
GNIEVYLDIK VPEQGSHFSV DPKNLLLKPG EEHEVIVSFT PKDPEACEER
1260 1270 1280 1290 1300
ILKIFVQPFG PQYEVVLKGE VISSGSKPLS PGPCLDIPSI LSNKQFLAWG
1310 1320 1330 1340 1350
GVPLGRTQLQ KLALRNNSAS TTQHLRLLIR GQDQDCFQLQ NTFGSEQRLT
1360 1370 1380 1390 1400
SNCEIRIHPK EDIFISVLFA PTRLSCMLAR LEIKQLGNRS QPGIKFTIPL
1410 1420 1430 1440 1450
SGYGGTSNLI LEGVKKLSDS YMVTVNGLVP GKESKIVFSV RNTGSRAAFV
1460 1470 1480 1490 1500
KAVGFKDSQK KVLLDPKVLR IFPDKFVLKE RTQENVTLIY NPSDRGINNK
1510 1520 1530 1540 1550
TATELSTVYL FGGDEISRQQ YRRALLHKPE MIKQILPEHS VLQNINFVEA
1560 1570 1580 1590 1600
FQDELLVTEV YDLPQRPNDV QLFYGSMCKI ILSVIGEFRD CISSREFLQP
1610 1620 1630 1640 1650
SSKASLESTS DLGASGKHGG NVSLDVLPVK GPQGSPLLSR AARPPLDQLA
1660 1670 1680 1690 1700
SEEPWTVLPE HLILVAPSPC DMAKTGRFQI VNNSVRLLRF ELCWPAHCLT
1710 1720 1730 1740 1750
VTPQHGCVAP ESKLQILVSP NSSLSTKQSM FPWSGLIYIH CDDGQKKIVK
1760 1770 1780 1790 1800
VQIREDLTQV ELLTRLTSKP FGILSPVSEP SVSHLVKPMT KPPSTKVEIR
1810 1820 1830 1840 1850
NKSITFPTTE PGETSESCLE LENHGTTDVK WHLSSLAPPY VKGVDESGDV
1860 1870 1880 1890 1900
FRATYAAFRC SPISGLLESH GIQKVSITFL PRGRGDYAQF WDVECHPLKE
1910 1920 1930 1940 1950
PHMKHTLRFQ LSGQSIEAEN EPENACLSTD SLIKIDHLVK PRRQAVSEAS
1960 1970 1980 1990 2000
ARIPEQLDVT ARGVYAPEDV YRFRPTSVGE SRTLKVNLRN NSFITHSLKF
2010 2020 2030 2040 2050
LSPREPFYVK HSKYSLRAQH YINMPVQFKP KSAGKFEALL VIQTDEGKSI
2060
AIRLIGEALG KN
Length:2,062
Mass (Da):226,993
Last modified:January 7, 2015 - v1
Checksum:i3BC0350DD507614D
GO

Computationally mapped potential isoform sequencesi

There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8TEP8CE192_HUMAN
Centrosomal protein of 192 kDa
CEP192 KIAA1569, PP8407
2,537Annotation score:
K7ENP4K7ENP4_HUMAN
Centrosomal protein of 192 kDa
CEP192
2,076Annotation score:
H0Y966H0Y966_HUMAN
Centrosomal protein of 192 kDa
CEP192
1,931Annotation score:
K7EPA2K7EPA2_HUMAN
Centrosomal protein of 192 kDa
CEP192
900Annotation score:
C9JT09C9JT09_HUMAN
Centrosomal protein of 192 kDa
CEP192
426Annotation score:
K7ELX0K7ELX0_HUMAN
Centrosomal protein of 192 kDa
CEP192
1,237Annotation score:
K7ERF9K7ERF9_HUMAN
Centrosomal protein of 192 kDa
CEP192
73Annotation score:
K7EQZ8K7EQZ8_HUMAN
Centrosomal protein of 192 kDa
CEP192
47Annotation score:
H0Y9P3H0Y9P3_HUMAN
Centrosomal protein of 192 kDa
CEP192
407Annotation score:
V9GYM2V9GYM2_HUMAN
Centrosomal protein of 192 kDa
CEP192
70Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001357 Genomic DNA No translation available.
AP002449 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000325971; ENSP00000317156; ENSG00000101639
UCSCiuc060npo.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001357 Genomic DNA No translation available.
AP002449 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliA0A0A0MR42
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiA0A0A0MR42
MaxQBiA0A0A0MR42
PeptideAtlasiA0A0A0MR42
PRIDEiA0A0A0MR42

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000325971; ENSP00000317156; ENSG00000101639
UCSCiuc060npo.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000101639.18
HGNCiHGNC:25515 CEP192
OpenTargetsiENSG00000101639
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IG8G Eukaryota
ENOG4110RMB LUCA
GeneTreeiENSGT00510000048187

Miscellaneous databases

ChiTaRSiCEP192 human

Gene expression databases

BgeeiENSG00000101639 Expressed in 203 organ(s), highest expression level in heart
ExpressionAtlasiA0A0A0MR42 baseline and differential

Family and domain databases

Gene3Di2.60.40.10, 3 hits
InterProiView protein in InterPro
IPR013783 Ig-like_fold
IPR039103 Spd-2/CEP192
PANTHERiPTHR16029 PTHR16029, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0A0MR42_HUMAN
AccessioniPrimary (citable) accession number: A0A0A0MR42
Entry historyiIntegrated into UniProtKB/TrEMBL: January 7, 2015
Last sequence update: January 7, 2015
Last modified: September 12, 2018
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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