UniProtKB - A0A0A0MQZ0 (A0A0A0MQZ0_HUMAN)
Protein
Submitted name:
Natural cytotoxicity triggering receptor 1
Gene
NCR1
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Natural cytotoxicity triggering receptor 1Imported |
Gene namesi | Name:NCR1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:6731, NCR1 |
VEuPathDBi | HostDB:ENSG00000189430.12 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 256 – 274 | HelicalSequence analysisAdd BLAST | 19 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 21 | Sequence analysisAdd BLAST | 21 | |
ChainiPRO_5014015973 | 22 – 304 | Sequence analysisAdd BLAST | 283 |
Expressioni
Gene expression databases
Bgeei | ENSG00000189430, Expressed in granulocyte and 98 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 34 – 115 | IGInterPro annotationAdd BLAST | 82 | |
Domaini | 129 – 211 | IGInterPro annotationAdd BLAST | 83 |
Keywords - Domaini
SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
GeneTreei | ENSGT01000000214458 |
OMAi | PVIWAKP |
OrthoDBi | 1327293at2759 |
Family and domain databases
Gene3Di | 2.60.40.10, 2 hits |
InterProi | View protein in InterPro IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003599, Ig_sub |
SMARTi | View protein in SMART SM00409, IG, 2 hits |
SUPFAMi | SSF48726, SSF48726, 2 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.Show allAlign All
A0A0A0MQZ0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSSTLPALLC VGLCLSQRIS AQQQTLPKPF IWAEPHFMVP KEKQVTICCQ
60 70 80 90 100
GNYGAVEYQL HFEGSLFAVD RPKPPERINK VQFYIPDMNS RMAGQYSCIY
110 120 130 140 150
RVGELWSEPS NLLDLVVTEM YDTPTLSVHP GPEVISGEKV TFYCRLDTAT
160 170 180 190 200
SMFLLLKEGR SSHVQRGYGK VQAEFPLGPV TTAHRGTYRC FGSYNNHAWS
210 220 230 240 250
FPSEPVKLLV TGDIENTSLA PEDPTFPADT WGTYLLTTET GLQKDHALWD
260 270 280 290 300
HTAQNLLRMG LAFLVLVALV WFLVEDWLSR KRTRERASRA STWEGRRRLN
TQTL
Computationally mapped potential isoform sequencesi
There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketO76036 | NCTR1_HUMAN | Natural cytotoxicity triggering rec... | NCR1 LY94 | 304 | Annotation score: | ||
A0A0G2JN91 | A0A0G2JN91_HUMAN | Natural cytotoxicity triggering rec... | NCR1 | 292 | Annotation score: | ||
A0A0G2JM39 | A0A0G2JM39_HUMAN | Natural cytotoxicity triggering rec... | NCR1 | 291 | Annotation score: | ||
A0A0G2JM44 | A0A0G2JM44_HUMAN | Natural cytotoxicity triggering rec... | NCR1 | 227 | Annotation score: | ||
A0A0G2JMJ3 | A0A0G2JMJ3_HUMAN | Natural cytotoxicity triggering rec... | NCR1 | 132 | Annotation score: | ||
A0A0A0MR94 | A0A0A0MR94_HUMAN | Natural cytotoxicity triggering rec... | NCR1 | 287 | Annotation score: | ||
A0A0A0MTU0 | A0A0A0MTU0_HUMAN | Natural cytotoxicity triggering rec... | NCR1 | 303 | Annotation score: | ||
M0QYD1 | M0QYD1_HUMAN | Natural cytotoxicity triggering rec... | NCR1 | 291 | Annotation score: | ||
A0A0G2JNH1 | A0A0G2JNH1_HUMAN | Natural cytotoxicity triggering rec... | NCR1 | 215 | Annotation score: | ||
A0A0G2JN63 | A0A0G2JN63_HUMAN | Natural cytotoxicity triggering rec... | NCR1 | 120 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC011476 Genomic DNA No translation available. AC245128 Genomic DNA No translation available. |
RefSeqi | NP_004820.2, NM_004829.6 |
Genome annotation databases
Ensembli | ENST00000291890; ENSP00000291890; ENSG00000189430 ENST00000638974; ENSP00000491346; ENSG00000284113 ENST00000638981; ENSP00000492155; ENSG00000284113 ENST00000676981; ENSP00000504366; ENSG00000288651 ENST00000678327; ENSP00000504264; ENSG00000288651 |
GeneIDi | 9437 |
KEGGi | hsa:9437 |
UCSCi | uc002qib.3, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC011476 Genomic DNA No translation available. AC245128 Genomic DNA No translation available. |
RefSeqi | NP_004820.2, NM_004829.6 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
Antibodypediai | 19469, 774 antibodies |
DNASUi | 9437 |
Genome annotation databases
Ensembli | ENST00000291890; ENSP00000291890; ENSG00000189430 ENST00000638974; ENSP00000491346; ENSG00000284113 ENST00000638981; ENSP00000492155; ENSG00000284113 ENST00000676981; ENSP00000504366; ENSG00000288651 ENST00000678327; ENSP00000504264; ENSG00000288651 |
GeneIDi | 9437 |
KEGGi | hsa:9437 |
UCSCi | uc002qib.3, human |
Organism-specific databases
CTDi | 9437 |
HGNCi | HGNC:6731, NCR1 |
OpenTargetsi | ENSG00000189430 |
VEuPathDBi | HostDB:ENSG00000189430.12 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT01000000214458 |
OMAi | PVIWAKP |
OrthoDBi | 1327293at2759 |
Miscellaneous databases
BioGRID-ORCSi | 9437, 0 hits in 985 CRISPR screens |
ChiTaRSi | NCR1, human |
GenomeRNAii | 9437 |
Gene expression databases
Bgeei | ENSG00000189430, Expressed in granulocyte and 98 other tissues |
Family and domain databases
Gene3Di | 2.60.40.10, 2 hits |
InterProi | View protein in InterPro IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003599, Ig_sub |
SMARTi | View protein in SMART SM00409, IG, 2 hits |
SUPFAMi | SSF48726, SSF48726, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A0A0MQZ0_HUMAN | |
Accessioni | A0A0A0MQZ0Primary (citable) accession number: A0A0A0MQZ0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | January 7, 2015 |
Last sequence update: | January 7, 2015 | |
Last modified: | April 7, 2021 | |
This is version 40 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |