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Protein
Submitted name:

Beta crystallin A4 chain

Gene

CRYBA4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Beta crystallin A4 chainImported
Submitted name:
Beta crystallin A4 chain transcript PSImported
Submitted name:
Beta crystallin alpha 4 chainImported
Submitted name:
Crystallin, beta A4Imported
Gene namesi
Name:CRYBA4Imported
Synonyms:CYRBA4Imported
ORF Names:hCG_41134Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000196431.3

Expressioni

Gene expression databases

BgeeiENSG00000196431 Expressed in 40 organ(s), highest expression level in lens of camera-type eye

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 51Beta/gamma crystallin 'Greek key'InterPro annotationAdd BLAST40
Domaini52 – 98Beta/gamma crystallin 'Greek key'InterPro annotationAdd BLAST47
Domaini105 – 146Beta/gamma crystallin 'Greek key'InterPro annotationAdd BLAST42
Domaini147 – 195Beta/gamma crystallin 'Greek key'InterPro annotationAdd BLAST49

Sequence similaritiesi

Belongs to the beta/gamma-crystallin family.SAAS annotation

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiENOG410IE7N Eukaryota
ENOG410YIM8 LUCA
OMAiWDGNEVG
OrthoDBiEOG091G0JYH

Family and domain databases

InterProiView protein in InterPro
IPR001064 Beta/gamma_crystallin
IPR033342 CRYBA4
IPR011024 G_crystallin-like
PANTHERiPTHR11818:SF19 PTHR11818:SF19, 1 hit
PfamiView protein in Pfam
PF00030 Crystall, 2 hits
PRINTSiPR01367 BGCRYSTALLIN
SMARTiView protein in SMART
SM00247 XTALbg, 2 hits
SUPFAMiSSF49695 SSF49695, 1 hit
PROSITEiView protein in PROSITE
PS50915 CRYSTALLIN_BETA_GAMMA, 4 hits

Sequencei

Sequence statusi: Complete.

A0A097PIJ6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTLQCTKSAG PWKMVVWDED GFQGRRHEFT AECPSVLELG FETVRSLKVL
60 70 80 90 100
SGAWVGFEHA GFQGQQYILE RGEYPSWDAW GGNTAYPAER LTSFRPAACA
110 120 130 140 150
NHRDSRLTIF EQENFLGKKG ELSDDYPSLQ AMGWEGNEVG SFHVHSGAWV
160 170 180 190
CSQFPGYRGF QYVLECDHHS GDYKHFREWG SHAPTFQVQS IRRIQQ
Length:196
Mass (Da):22,374
Last modified:January 7, 2015 - v1
Checksum:i104EC68E3CDE5740
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KM230606 mRNA Translation: AIU47349.1
KM365088 mRNA Translation: AIY26924.1
KM365089 mRNA Translation: AIY26925.1
KM365090 mRNA Translation: AIY26926.1
KU342019 Genomic DNA Translation: AMM45326.1
CH471095 Genomic DNA Translation: EAW59731.1
RefSeqiNP_001877.1, NM_001886.2
UniGeneiHs.57690

Genome annotation databases

GeneIDi1413
KEGGihsa:1413

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KM230606 mRNA Translation: AIU47349.1
KM365088 mRNA Translation: AIY26924.1
KM365089 mRNA Translation: AIY26925.1
KM365090 mRNA Translation: AIY26926.1
KU342019 Genomic DNA Translation: AMM45326.1
CH471095 Genomic DNA Translation: EAW59731.1
RefSeqiNP_001877.1, NM_001886.2
UniGeneiHs.57690

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1413
KEGGihsa:1413

Organism-specific databases

CTDi1413
EuPathDBiHostDB:ENSG00000196431.3

Phylogenomic databases

eggNOGiENOG410IE7N Eukaryota
ENOG410YIM8 LUCA
OMAiWDGNEVG
OrthoDBiEOG091G0JYH

Miscellaneous databases

GenomeRNAii1413

Gene expression databases

BgeeiENSG00000196431 Expressed in 40 organ(s), highest expression level in lens of camera-type eye

Family and domain databases

InterProiView protein in InterPro
IPR001064 Beta/gamma_crystallin
IPR033342 CRYBA4
IPR011024 G_crystallin-like
PANTHERiPTHR11818:SF19 PTHR11818:SF19, 1 hit
PfamiView protein in Pfam
PF00030 Crystall, 2 hits
PRINTSiPR01367 BGCRYSTALLIN
SMARTiView protein in SMART
SM00247 XTALbg, 2 hits
SUPFAMiSSF49695 SSF49695, 1 hit
PROSITEiView protein in PROSITE
PS50915 CRYSTALLIN_BETA_GAMMA, 4 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A097PIJ6_HUMAN
AccessioniPrimary (citable) accession number: A0A097PIJ6
Entry historyiIntegrated into UniProtKB/TrEMBL: January 7, 2015
Last sequence update: January 7, 2015
Last modified: October 10, 2018
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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