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Protein
Submitted name:

Syntaxin-binding protein 1

Gene

STXBP1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Syntaxin-binding protein 1Imported
Gene namesi
Name:STXBP1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

EuPathDBiHostDB:ENSG00000136854.17
HGNCiHGNC:11444 STXBP1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000136854

PTM / Processingi

Proteomic databases

EPDiA0A096LP52
PeptideAtlasiA0A096LP52

Expressioni

Gene expression databases

BgeeiENSG00000136854 Expressed in 224 organ(s), highest expression level in primary visual cortex
ExpressionAtlasiA0A096LP52 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A096LP52
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the STXBP/unc-18/SEC1 family.SAAS annotation

Phylogenomic databases

eggNOGiKOG1300 Eukaryota
COG5158 LUCA
GeneTreeiENSGT00390000005206

Family and domain databases

Gene3Di3.40.50.1910, 1 hit
InterProiView protein in InterPro
IPR027482 Sec-1-like_dom2
IPR001619 Sec1-like
IPR036045 Sec1-like_sf
PANTHERiPTHR11679 PTHR11679, 1 hit
PfamiView protein in Pfam
PF00995 Sec1, 1 hit
SUPFAMiSSF56815 SSF56815, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 15 potential isoforms that are computationally mapped.Show allAlign All

A0A096LP52-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
IMEDTIEDKL DTKHYPYIST RSSASFSTTA VSARYGHWHK NKAPGEYRSG
60 70 80 90 100
PRLIIFILGG VSLNEMRCAY EVTQANGKWE VLIGSTHILT PTKFLMDLRH
110
PDFRESSRVS FEDQAPTME
Length:119
Mass (Da):13,567
Last modified:November 26, 2014 - v1
Checksum:i17464126F49F9440
GO

Computationally mapped potential isoform sequencesi

There are 15 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P61764STXB1_HUMAN
Syntaxin-binding protein 1
STXBP1 UNC18A
594Annotation score:
A0A0D9SG72A0A0D9SG72_HUMAN
Syntaxin-binding protein 1
STXBP1
580Annotation score:
A0A1B0GVQ5A0A1B0GVQ5_HUMAN
Syntaxin-binding protein 1
STXBP1
577Annotation score:
A0A1B0GTP9A0A1B0GTP9_HUMAN
Syntaxin-binding protein 1
STXBP1
589Annotation score:
A0A1B0GWF2A0A1B0GWF2_HUMAN
Syntaxin-binding protein 1
STXBP1
574Annotation score:
A0A096LP33A0A096LP33_HUMAN
Syntaxin-binding protein 1
STXBP1
75Annotation score:
A0A0D9SEP9A0A0D9SEP9_HUMAN
Syntaxin-binding protein 1
STXBP1
100Annotation score:
A0A0D9SFQ7A0A0D9SFQ7_HUMAN
Syntaxin-binding protein 1
STXBP1
147Annotation score:
A0A0D9SEH5A0A0D9SEH5_HUMAN
Syntaxin-binding protein 1
STXBP1
102Annotation score:
A0A0D9SFW6A0A0D9SFW6_HUMAN
Syntaxin-binding protein 1
STXBP1
149Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL162426 Genomic DNA No translation available.
AL390116 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000494254; ENSP00000485397; ENSG00000136854
UCSCiuc064vwf.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL162426 Genomic DNA No translation available.
AL390116 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliA0A096LP52
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiA0A096LP52
PeptideAtlasiA0A096LP52

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000494254; ENSP00000485397; ENSG00000136854
UCSCiuc064vwf.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000136854.17
HGNCiHGNC:11444 STXBP1
OpenTargetsiENSG00000136854
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1300 Eukaryota
COG5158 LUCA
GeneTreeiENSGT00390000005206

Miscellaneous databases

ChiTaRSiSTXBP1 human

Gene expression databases

BgeeiENSG00000136854 Expressed in 224 organ(s), highest expression level in primary visual cortex
ExpressionAtlasiA0A096LP52 baseline and differential

Family and domain databases

Gene3Di3.40.50.1910, 1 hit
InterProiView protein in InterPro
IPR027482 Sec-1-like_dom2
IPR001619 Sec1-like
IPR036045 Sec1-like_sf
PANTHERiPTHR11679 PTHR11679, 1 hit
PfamiView protein in Pfam
PF00995 Sec1, 1 hit
SUPFAMiSSF56815 SSF56815, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A096LP52_HUMAN
AccessioniPrimary (citable) accession number: A0A096LP52
Entry historyiIntegrated into UniProtKB/TrEMBL: November 26, 2014
Last sequence update: November 26, 2014
Last modified: September 12, 2018
This is version 30 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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