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Protein
Submitted name:

CASP8-associated protein 2

Gene

CASP8AP2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
CASP8-associated protein 2Imported
Gene namesi
Name:CASP8AP2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000118412.12
HGNCiHGNC:1510 CASP8AP2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000118412

Expressioni

Gene expression databases

BgeeiENSG00000118412 Expressed in 212 organ(s), highest expression level in corpus callosum

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili73 – 93Sequence analysisAdd BLAST21
Coiled coili119 – 139Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

GeneTreeiENSGT00620000088063

Family and domain databases

InterProiView protein in InterPro
IPR039674 FLASH
PANTHERiPTHR15489 PTHR15489, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

A0A096LP21-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAADDDNGDG TSLFDVFSAS PLKNNDEGSL DIYAGLDSAV SDSASKSCVP
60 70 80 90 100
SRNCLDLYEE ILTEEGTAKE ATYNDLQVEY GKCQLQMKEL MKKFKEIQTQ
110 120 130 140 150
NFSLINENQS LKKNISALIK TARVEINRKD EEISNLHQRL SEFPHFRNNH
160 170 180 190 200
KTARTFDTVK TKDLKSRSPH LDDCSKTDHR AKSDVSKDVH HSTSLPNLEK
210 220 230 240 250
EGKPHSDKRS TSHLPTSVEK HCTNGVWSRS HYQVGEGSSN EDSRRGRKDI
260 270 280 290 300
RHSQFNRGTE RVRKDLSTGC GDGEPRILEA SQRLQGHPEK YGKGEPKTES
310 320 330 340 350
KSSKFKSNSD SDYKGERINS SWEKETPGER SHSRVDSQSD KKLERQSERS
360
QNINRKEVKS Q
Length:361
Mass (Da):40,892
Last modified:November 26, 2014 - v1
Checksum:i9EE43B99E54D2DA4
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9UKL3C8AP2_HUMAN
CASP8-associated protein 2
CASP8AP2 FLASH, KIAA1315, RIP25
1,982Annotation score:
A0A087WTW5A0A087WTW5_HUMAN
CASP8-associated protein 2
CASP8AP2
1,972Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei361Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL353692 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000419040; ENSP00000485349; ENSG00000118412
ENST00000552401; ENSP00000485346; ENSG00000118412
UCSCiuc063qch.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL353692 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000419040; ENSP00000485349; ENSG00000118412
ENST00000552401; ENSP00000485346; ENSG00000118412
UCSCiuc063qch.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000118412.12
HGNCiHGNC:1510 CASP8AP2
OpenTargetsiENSG00000118412
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00620000088063

Miscellaneous databases

ChiTaRSiCASP8AP2 human

Gene expression databases

BgeeiENSG00000118412 Expressed in 212 organ(s), highest expression level in corpus callosum

Family and domain databases

InterProiView protein in InterPro
IPR039674 FLASH
PANTHERiPTHR15489 PTHR15489, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A096LP21_HUMAN
AccessioniPrimary (citable) accession number: A0A096LP21
Entry historyiIntegrated into UniProtKB/TrEMBL: November 26, 2014
Last sequence update: November 26, 2014
Last modified: November 7, 2018
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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