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UniProtKB - A0A095L472 (A0A095L472_BURPE)

Entry version 47 (02 Dec 2020)
Sequence version 1 (26 Nov 2014)
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Protein
Submitted name:

Phosphoenolpyruvate mutase

Gene

pphA_2

Organism
Burkholderia pseudomallei (Pseudomonas pseudomallei)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolaseImported, IsomeraseImported, TransferaseARBA annotation
LigandPyruvateImported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Phosphoenolpyruvate mutaseImported (EC:5.4.2.9Imported)
Submitted name:
Phosphoenolpyruvate phosphomutaseImported (EC:3.11.1.3Imported)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:pphA_2Imported
Synonyms:aepXImported
ORF Names:BOC42_27090Imported, CXQ84_23745Imported, DF122_32355Imported, ERS013345_00617Imported, SAMEA1968934_01268Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBurkholderia pseudomallei (Pseudomonas pseudomallei)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28450 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000038379 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000193684 Componenti: Chromosome 2
  • UP000276024 Componenti: Unassembled WGS sequence
  • UP000276823 Componenti: Unassembled WGS sequence
  • UP000233327 Componenti: Chromosome 2

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini307 – 432NTP_transf_3InterPro annotationAdd BLAST126

Family and domain databases

Conserved Domains Database

More...CDDi		cd00377, ICL_PEPM, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.20.20.60, 1 hit
3.90.550.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR039556, ICL/PEPM
IPR025877, MobA-like_NTP_Trfase
IPR029044, Nucleotide-diphossugar_trans
IPR012698, PEnolPyrv_PMutase_core
IPR015813, Pyrv/PenolPyrv_Kinase-like_dom
IPR040442, Pyrv_Kinase-like_dom_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF12804, NTP_transf_3, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF51621, SSF51621, 1 hit
SSF53448, SSF53448, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR02320, PEP_mutase, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A095L472-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNAREPNFTE SRSARLRRML TSPSLEFLME AHNGLSARIV REAGFKGIWA 
        60         70         80         90        100
SGLAISAQFG VRDNNEASWT QVVDVLEFMA DASDLPILLD GDTGYGNFNN 
       110        120        130        140        150
VRRLVRKLEQ RGIAGVCIED KQFPKTNSFI DGERQPLAEI DEFCGKIKAG 
       160        170        180        190        200
KDSQSDPDFS IVARVEALIA GWGMDEALRR ANAYAQAGAD AILIHSKLSR 
       210        220        230        240        250
PDEILQFARE WSGRAPLVIV PTKYYSTPTD VFRQAGISTV IWANHLIRAS 
       260        270        280        290        300
ASAMQAVARE IQDSETLVNV EERVASVNEI FRLQDADEYS AAERIYLSSS 
       310        320        330        340        350
ARASSAALVL AASRGNGLEA VTEDKPKVML PVAGKPLLRW LVDGFKKQGV 
       360        370        380        390        400
NDITVVGGYR ADAIDTSGVK LVVNERHAQT GELASLACAA ERLTGDTIIS 
       410        420        430        440        450
YGDLLFRSYI LRDLAESEAQ FSVVVDSSQT QPSNQSVRDF AFCSAADDRG 
       460        470        480        490        500
LFGQKAYLRR VSSDASEAAP HGRWIGLLNV RGAGVARLKA MLGTLQARDD 
       510        520        530        540        550
FDALDLPALL NALVDAGEQI EVQYVHGHWR GVNDLDDFRR AGDFAHGQTP 
       560 
YAEQNAGSGS AR
Length:562
Mass (Da):61,258
Last modified:November 26, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD1E1AEDE5C430884
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
CP018381 Genomic DNA Translation: ARK90913.1
CP025265 Genomic DNA Translation: AUG23578.1
CSKM01000001 Genomic DNA Translation: CPF02411.1
RSFB01000035 Genomic DNA Translation: RSK57479.1
UVEN01000008 Genomic DNA Translation: VBX99134.1

NCBI Reference Sequences

More...RefSeqi		WP_004525540.1, NZ_WUTV01000030.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...GeneIDi		45699870

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		but:X994_4111

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP018381 Genomic DNA Translation: ARK90913.1
CP025265 Genomic DNA Translation: AUG23578.1
CSKM01000001 Genomic DNA Translation: CPF02411.1
RSFB01000035 Genomic DNA Translation: RSK57479.1
UVEN01000008 Genomic DNA Translation: VBX99134.1
RefSeqiWP_004525540.1, NZ_WUTV01000030.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

GeneIDi45699870
KEGGibut:X994_4111

Family and domain databases

CDDicd00377, ICL_PEPM, 1 hit
Gene3Di3.20.20.60, 1 hit
3.90.550.10, 1 hit
InterProiView protein in InterPro
IPR039556, ICL/PEPM
IPR025877, MobA-like_NTP_Trfase
IPR029044, Nucleotide-diphossugar_trans
IPR012698, PEnolPyrv_PMutase_core
IPR015813, Pyrv/PenolPyrv_Kinase-like_dom
IPR040442, Pyrv_Kinase-like_dom_sf
PfamiView protein in Pfam
PF12804, NTP_transf_3, 1 hit
SUPFAMiSSF51621, SSF51621, 1 hit
SSF53448, SSF53448, 1 hit
TIGRFAMsiTIGR02320, PEP_mutase, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A095L472_BURPE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A095L472
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 26, 2014
Last sequence update: November 26, 2014
Last modified: December 2, 2020
This is version 47 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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