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Protein
Submitted name:

Cadherin-18

Gene

N307_11477

Organism
Dryobates pubescens (Downy woodpecker) (Picoides pubescens)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Cadherins are calcium-dependent cell adhesion proteins.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell adhesionUniRule annotationSAAS annotation
LigandCalciumUniRule annotationSAAS annotation, Metal-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Cadherin-18Imported
Gene namesi
ORF Names:N307_11477Imported
OrganismiDryobates pubescens (Downy woodpecker) (Picoides pubescens)Imported
Taxonomic identifieri118200 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaePiciformesPicidaePicoides
Proteomesi
  • UP000053875 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei615 – 636HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_500188424325 – 790Sequence analysisAdd BLAST766

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini76 – 157CAInterPro annotationAdd BLAST82
Domaini181 – 266CAInterPro annotationAdd BLAST86
Domaini290 – 382CAInterPro annotationAdd BLAST93
Domaini405 – 486CAInterPro annotationAdd BLAST82
Domaini509 – 596CAInterPro annotationAdd BLAST88

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

Gene3Di4.10.900.10, 1 hit
InterProiView protein in InterPro
IPR039808 Cadherin
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR020894 Cadherin_CS
IPR000233 Cadherin_cytoplasmic-dom
IPR027397 Catenin_binding_dom_sf
PANTHERiPTHR24027 PTHR24027, 1 hit
PfamiView protein in Pfam
PF00028 Cadherin, 5 hits
PF01049 Cadherin_C, 1 hit
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 5 hits
SUPFAMiSSF49313 SSF49313, 5 hits
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 2 hits

Sequencei

Sequence statusi: Complete.

A0A093FXK2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRITSTSCIC PVLVCLCFVQ RCYGAAHHGS IKVTRNQTKH IEGETEVHHR
60 70 80 90 100
PKRGWVWNQF FVLEEHMGPD PQYVGKLHSN SDKGDGSVKY ILTGEGAGTI
110 120 130 140 150
FIIDDTTGDI HSTKSLDREQ KTHYVLHAQA IDRRTNKPLE PESEFIIKVQ
160 170 180 190 200
DINDNAPKFT DGPYIVTVPE MSEMGTSVLQ VTATDADDPT YGNSARVVYS
210 220 230 240 250
ILQGQPYFSV DPKTGVIRTA LHNMDREARE HYSVVIQAKD MAGQVGGLSG
260 270 280 290 300
STTVNITLTD VNDNPPRFPQ KHYQLYVPES AQVGSAVGKI KANDADTGSN
310 320 330 340 350
ADMKYTIING DGSGVFSIST DKETREGILS LKKPLNYEKK KSYTLNIEGA
360 370 380 390 400
NTHLDFRFSH LGPFKDVTML KIIVGDVDEP PLFTMPSYVM EVYENAKIGT
410 420 430 440 450
AIGTVTAQDP DTANSLVRYI IDHNTEEDKY FTIDASTGTI KTAKIFDREE
460 470 480 490 500
TPWYNITVTA SEIDNPGLVS HVPVGVRILD INDNPPELAR EYDVVVCENA
510 520 530 540 550
KPGQVIQTIT ATDKDNSANG ARFHFFLDEG HSLNPNFTLR DNEDNTASIL
560 570 580 590 600
TRRKKYSRTT QDMYYLPVLI SDGGVPSLSS SSTLTIKVCA CERDGRVRTC
610 620 630 640 650
HAEAFLSSAG LSTGALIAIL LCVVILLAIV VLFVTLRRNK KEPLIISEED
660 670 680 690 700
VRENVVTYDD EGGGEEDTEA FDITALRNPS AAEELKYRRD VRPEVKPMPR
710 720 730 740 750
HLTSTSLDSI DVQEFIKQRL AEADLDPSVP PYDSLQTYAY EGHRSEAGSI
760 770 780 790
SSLDSATTHS DQDYNYLEDW GPEFKKLAEL YGEIESERTT
Length:790
Mass (Da):87,637
Last modified:November 26, 2014 - v1
Checksum:i76D90110DAF86D08
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KL214977 Genomic DNA Translation: KFV62670.1
RefSeqiXP_009908451.1, XM_009910149.1

Genome annotation databases

GeneIDi104308906

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KL214977 Genomic DNA Translation: KFV62670.1
RefSeqiXP_009908451.1, XM_009910149.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi104308906

Organism-specific databases

CTDi1016

Family and domain databases

Gene3Di4.10.900.10, 1 hit
InterProiView protein in InterPro
IPR039808 Cadherin
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR020894 Cadherin_CS
IPR000233 Cadherin_cytoplasmic-dom
IPR027397 Catenin_binding_dom_sf
PANTHERiPTHR24027 PTHR24027, 1 hit
PfamiView protein in Pfam
PF00028 Cadherin, 5 hits
PF01049 Cadherin_C, 1 hit
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 5 hits
SUPFAMiSSF49313 SSF49313, 5 hits
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A093FXK2_DRYPU
AccessioniPrimary (citable) accession number: A0A093FXK2
Entry historyiIntegrated into UniProtKB/TrEMBL: November 26, 2014
Last sequence update: November 26, 2014
Last modified: November 7, 2018
This is version 23 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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