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Entry version 25 (31 Jul 2019)
Sequence version 1 (26 Nov 2014)
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Protein
Submitted name:

Transcriptional-regulating factor 1

Gene

N334_05725

Organism
Pelecanus crispus (Dalmatian pelican)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Transcriptional-regulating factor 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:N334_05725Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPelecanus crispus (Dalmatian pelican)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri36300 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaePelecaniformesPelecanidaePelecanus

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini493 – 520C2H2-typeInterPro annotationAdd BLAST28
Domaini753 – 844ELM2InterPro annotationAdd BLAST92
Domaini859 – 910SANTInterPro annotationAdd BLAST52
Domaini981 – 1010C2H2-typeInterPro annotationAdd BLAST30
Domaini1053 – 1080C2H2-typeInterPro annotationAdd BLAST28

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni38 – 109DisorderedSequence analysisAdd BLAST72
Regioni271 – 300DisorderedSequence analysisAdd BLAST30
Regioni321 – 355DisorderedSequence analysisAdd BLAST35
Regioni386 – 487DisorderedSequence analysisAdd BLAST102
Regioni508 – 539DisorderedSequence analysisAdd BLAST32
Regioni558 – 583DisorderedSequence analysisAdd BLAST26
Regioni599 – 618DisorderedSequence analysisAdd BLAST20
Regioni929 – 960DisorderedSequence analysisAdd BLAST32
Regioni1018 – 1050DisorderedSequence analysisAdd BLAST33

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1069 – 1096Sequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi38 – 57PolarSequence analysisAdd BLAST20
Compositional biasi69 – 109PolarSequence analysisAdd BLAST41
Compositional biasi386 – 423PolarSequence analysisAdd BLAST38
Compositional biasi441 – 480PolarSequence analysisAdd BLAST40
Compositional biasi558 – 577PolarSequence analysisAdd BLAST20
Compositional biasi600 – 615PolarSequence analysisAdd BLAST16
Compositional biasi930 – 945AcidicSequence analysisAdd BLAST16

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotation

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000949 ELM2_dom
IPR009057 Homeobox-like_sf
IPR001005 SANT/Myb
IPR017884 SANT_dom
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01448 ELM2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01189 ELM2, 1 hit
SM00717 SANT, 1 hit
SM00355 ZnF_C2H2, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46689 SSF46689, 1 hit
SSF57667 SSF57667, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51156 ELM2, 1 hit
PS51293 SANT, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 2 hits
PS50157 ZINC_FINGER_C2H2_2, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A091SKK7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGDQQLYKTN HTANSNENLY YQQHQMNSLP SLNHSYGTSV MDAPQASPLS
60 70 80 90 100
PQFPQDSRDS IALPVGSKSL GSMDTSRQTS WTHSGSGNHV PVRNNLNNQS
110 120 130 140 150
AMWSPLGQGE SHDGYQYSYS QPSENRSQKI TSGVLHKLDS FTQVFANQNL
160 170 180 190 200
RIQVNNMAQV LHTESSMVDN SGDSALRQLL SQKPAVEQQP VTSSVQRYQP
210 220 230 240 250
VPQQTHQNFA STQQKQQMQV MQHQQLYYDY QQHLSQMQMH SAFQQGQTHV
260 270 280 290 300
QQMQSQQLLP QQMQHLQQTQ YYAQPQQGHQ RLSIHEIQQQ QQQPTRQQQQ
310 320 330 340 350
RQCPMQIAQY YQTQPVMQQL QQQQQQMQLP LPPYHREPDP KTMHEPHQYP
360 370 380 390 400
QDPNHPVQLI QLGAVPQYCY QDPHEQYRHL YPQSLLQQQD QQKQYLSESR
410 420 430 440 450
APSLNSHVGL TPPETTEDPA RQEINSVGNA IPHRTLLPPS GVHLNNKSSQ
460 470 480 490 500
QDSPSTAWPQ VQLSDGRLQS LSPEQSGQNR ETLPERADAK NKLMCSICLK
510 520 530 540 550
EFKSLPALNG HMRSHGGVRA SPNFKQDEGE KPPQQPLPKE VDSLAPIVMP
560 570 580 590 600
VSVPVKLLSP EPSTQPSAST ATVKDKPANS VSDDEMPVLV KMTYSPPCSP
610 620 630 640 650
KVANPCSSSE ISKRPHQSAV KLEENFKPLQ DKKKYRHRPE PLFIPPPSFN
660 670 680 690 700
FSMSHSGATL YQSQLRSPRV LGDHLLDRTH ELPPYTPPPM LSPVRQGSGL
710 720 730 740 750
FSSVITSSHS TSHTQLPLTP LTPTPRVLLC RSNSIDGSVI PVTPGPGEQT
760 770 780 790 800
VEPRINIGSR FQADIPELQD RLLMEKDVHK ATLVWKPWPE LENKVFQQRV
810 820 830 840 850
EDLLNMSCSS VLPGGGTNSE YALHSLFEAK GDIMVALEKL LLRKPVRLKC
860 870 880 890 900
HPLANYHYAG SDKWTHQERR LFKEALSTYS KDFIFVQKMV KSKTVAQCVE
910 920 930 940 950
YYYTWKKILR LGRKHRTRLE KKREECLTSG EEEVLEEDEE IEEDRKEDRE
960 970 980 990 1000
MQKSPDPPAI PLVGPIDLPA LQSLSLSSSS FICEMPNCGA VRVSRQALNG
1010 1020 1030 1040 1050
HARIHGGTNQ VTKTRCTIPG TKQKSGTQSG YCSIKSSPAH STTSGETDPT
1060 1070 1080 1090 1100
TIFPCKECGK VFFKIKSRNA HMKTHRQQEE QQRQKAQKAA VAAEMAATIA
1110 1120 1130 1140 1150
RTTGPVGHSL IPLDHMSLVK HVENVGDIDD DVVQELGDVM EENEVMDADL
1160
LLDDEDADLL QDDAEL
Length:1,166
Mass (Da):131,303
Last modified:November 26, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i73EE74985FBF3BE8
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
KK476511 Genomic DNA Translation: KFQ59169.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KK476511 Genomic DNA Translation: KFQ59169.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

InterProiView protein in InterPro
IPR000949 ELM2_dom
IPR009057 Homeobox-like_sf
IPR001005 SANT/Myb
IPR017884 SANT_dom
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01448 ELM2, 1 hit
SMARTiView protein in SMART
SM01189 ELM2, 1 hit
SM00717 SANT, 1 hit
SM00355 ZnF_C2H2, 3 hits
SUPFAMiSSF46689 SSF46689, 1 hit
SSF57667 SSF57667, 1 hit
PROSITEiView protein in PROSITE
PS51156 ELM2, 1 hit
PS51293 SANT, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 2 hits
PS50157 ZINC_FINGER_C2H2_2, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A091SKK7_PELCR
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A091SKK7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 26, 2014
Last sequence update: November 26, 2014
Last modified: July 31, 2019
This is version 25 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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