Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 25 (11 Dec 2019)
Sequence version 1 (26 Nov 2014)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein
Submitted name:

Protein transport protein Sec31A

Gene

H920_00694

Organism
Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Protein transport protein Sec31AImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:H920_00694Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiFukomys damarensis (Damaraland mole rat) (Cryptomys damarensis)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri885580 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaHystricomorphaBathyergidaeFukomys
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000028990 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
885580.XP_010627150.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini269 – 492WD_REPEATS_REGIONInterPro annotationAdd BLAST224
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati269 – 311WDPROSITE-ProRule annotationAdd BLAST43

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni51 – 74DisorderedSequence analysisAdd BLAST24
Regioni942 – 977DisorderedSequence analysisAdd BLAST36
Regioni995 – 1090DisorderedSequence analysisAdd BLAST96
Regioni1119 – 1276DisorderedSequence analysisAdd BLAST158

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1321 – 1341Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi52 – 73PolarSequence analysisAdd BLAST22
Compositional biasi995 – 1013PolarSequence analysisAdd BLAST19
Compositional biasi1014 – 1028Pro-richSequence analysisAdd BLAST15
Compositional biasi1119 – 1142PolarSequence analysisAdd BLAST24
Compositional biasi1150 – 1179PolarSequence analysisAdd BLAST30
Compositional biasi1206 – 1224PolarSequence analysisAdd BLAST19
Compositional biasi1225 – 1239Pro-richSequence analysisAdd BLAST15
Compositional biasi1247 – 1261PolarSequence analysisAdd BLAST15

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis, WD repeatPROSITE-ProRule annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.130.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR040251 SEC31-like
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR13923 PTHR13923, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00320 WD40, 6 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50978 SSF50978, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50082 WD_REPEATS_2, 1 hit
PS50294 WD_REPEATS_REGION, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A091E0J9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKFPCHDQPH LARIGPALWI WAESKQSETL GSRGEKFDPY SCFRRKHLTL
60 70 80 90 100
DPKTTTGNQD SDKGTSKATG QAVRQSVKIR IGEAESEVSR IRGMPMGPRR
110 120 130 140 150
RSLRRAAVLG SDRRVVGVFG DMSVTPGETE DAPIVNAGSL AAMGEVREID
160 170 180 190 200
RMKLKEVDRT AMQAWSPAQN HPIYLATGTS AQQLDATFST SASLEVFELD
210 220 230 240 250
LSDPSLDMKS CATFSSSQRY HKLIWGPHKT DAKGDLSGVL IAGGENGNII
260 270 280 290 300
LYDPSKIIAG DKEVVIAQND KHTGPVRALD VNIFQTNLVA SGANESEIYI
310 320 330 340 350
WDLNNFATPM TPGAKTQPPE DISCIAWNRQ VQHILASASP SGRATVWDLR
360 370 380 390 400
KNEPIIKVSD HSNKMHCSGL AWHPDVATQM VLSSEDDRLP VIQMWDLRFA
410 420 430 440 450
TCPLRVLENH ARGILAIAWS MADPELLLSC GKDAKILCSN PNTGEVLYEL
460 470 480 490 500
PTNTQWCFDI QWCPRNPAVL SAASFDGRIS VYSVMGGSTD GLRQKQVDKL
510 520 530 540 550
SSSFGNLDPF GTGQPLPPLQ IPQQTGQHSI VLPLKKPPKW IRRPVGASFS
560 570 580 590 600
FGGKLVTFEG VKTQPSQGAE QQQQHHHVFI SQVVTEKEFL SRSDQLQQVV
610 620 630 640 650
QSQGFISYCQ KKIDASQTEF EKNVWSFLKV NFEDDSRGKY LELLGFRKED
660 670 680 690 700
LGKKIALALN KVDGSNVALR DSDQVAQSDG EESSAAEEQL LGECIKEEKQ
710 720 730 740 750
ESEFLPSAGG TFNISVNGDI DGLITQALLT GNFESAVDLC LHDNRMADAI
760 770 780 790 800
ILAIAGGQEL LARTQKKYFA KSQSKITRLI TAVVMKNWKD IVESCDLKNW
810 820 830 840 850
REALAAVLTY AKPNEFPSLC DLLGARLESE GDGILQTQAC LCYICAGNVE
860 870 880 890 900
KLVACWTKAQ DSSSPLSLQD LIEKVIILRK AVQLTQTMDT NTVGVLLAEK
910 920 930 940 950
MSQYANLLAA QGSIAAALAF LPDNTNQPNI VQLRDRLCRA QGEPVPGQQS
960 970 980 990 1000
PKTPYERQQL AKGRPGPVAG HPQMPRAPNQ QYYTHVRIAP TATTWSNKTP
1010 1020 1030 1040 1050
TALPSHPPAA SPSDTQIENP PPPPGFIMHG NVNPNAAAQL PTSPGHMHSQ
1060 1070 1080 1090 1100
VPPYPQPQPY QAAQQYSFGT GGPAMYRPQQ PSAPPASSAY PNTPYISSAA
1110 1120 1130 1140 1150
SYSGQAPLYS AQHLASSPTS TSAAAFPPPS SLGSSFQHGG PGAPPSSSAY
1160 1170 1180 1190 1200
ALPPGTTENL SVQDQTPMFE GSQNGWNDPP ALNRVPKKKK MPENFMPPVP
1210 1220 1230 1240 1250
ITSPIMNPLS DPQSQMLQQQ PPAPGPLSNQ APYPQPHPLG GQPFHGLQQP
1260 1270 1280 1290 1300
LGQTSVPTSF PKPNIEGAPG APIGNTIQHV QSLPTEKITK KPIPDEHLIL
1310 1320 1330 1340 1350
KTTFEDLIQR CLSSATDPQT KRKLDDASKR LEFLYDKLRE QTLSPTIISG
1360 1370 1380 1390 1400
LHNIARSIET RNYSEGLTIH THIVSTSNFS ETSAFMPVLK VVLTQANKLG

V
Length:1,401
Mass (Da):152,527
Last modified:November 26, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7687AC642FB5B0F1
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
KN120688 Genomic DNA Translation: KFO37899.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KN120688 Genomic DNA Translation: KFO37899.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi885580.XP_010627150.1

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR040251 SEC31-like
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PANTHERiPTHR13923 PTHR13923, 1 hit
SMARTiView protein in SMART
SM00320 WD40, 6 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS50082 WD_REPEATS_2, 1 hit
PS50294 WD_REPEATS_REGION, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A091E0J9_FUKDA
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A091E0J9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 26, 2014
Last sequence update: November 26, 2014
Last modified: December 11, 2019
This is version 25 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again