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Protein
Submitted name:

Desmoplakin

Gene

H920_04763

Organism
Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
DesmoplakinImported
Gene namesi
ORF Names:H920_04763Imported
OrganismiFukomys damarensis (Damaraland mole rat) (Cryptomys damarensis)Imported
Taxonomic identifieri885580 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaHystricomorphaBathyergidaeFukomys
Proteomesi
  • UP000028990 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1090 – 1147SH3InterPro annotationAdd BLAST58

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili767 – 787Sequence analysisAdd BLAST21
Coiled coili951 – 971Sequence analysisAdd BLAST21
Coiled coili1043 – 1073Sequence analysisAdd BLAST31
Coiled coili1341 – 1361Sequence analysisAdd BLAST21
Coiled coili1443 – 1463Sequence analysisAdd BLAST21
Coiled coili1659 – 1679Sequence analysisAdd BLAST21
Coiled coili1687 – 1777Sequence analysisAdd BLAST91
Coiled coili1803 – 1841Sequence analysisAdd BLAST39
Coiled coili1857 – 1905Sequence analysisAdd BLAST49
Coiled coili1938 – 1979Sequence analysisAdd BLAST42
Coiled coili2027 – 2082Sequence analysisAdd BLAST56
Coiled coili2098 – 2180Sequence analysisAdd BLAST83
Coiled coili2188 – 2215Sequence analysisAdd BLAST28
Coiled coili2223 – 2243Sequence analysisAdd BLAST21
Coiled coili2272 – 2313Sequence analysisAdd BLAST42
Coiled coili2321 – 2376Sequence analysisAdd BLAST56
Coiled coili2395 – 2436Sequence analysisAdd BLAST42
Coiled coili2444 – 2577Sequence analysisAdd BLAST134

Keywords - Domaini

Coiled coilSequence analysis, SH3 domainPROSITE-ProRule annotation

Family and domain databases

Gene3Di3.90.1290.10, 3 hits
InterProiView protein in InterPro
IPR028462 Desmoplakin
IPR011009 Kinase-like_dom_sf
IPR035915 Plakin_repeat_sf
IPR001101 Plectin_repeat
IPR000687 RIO_kinase
IPR018935 RIO_kinase_CS
IPR001452 SH3_domain
IPR018159 Spectrin/alpha-actinin
PANTHERiPTHR44773 PTHR44773, 1 hit
PfamiView protein in Pfam
PF00681 Plectin, 8 hits
SMARTiView protein in SMART
SM00250 PLEC, 18 hits
SM00090 RIO, 1 hit
SM00150 SPEC, 3 hits
SUPFAMiSSF56112 SSF56112, 1 hit
SSF75399 SSF75399, 5 hits
PROSITEiView protein in PROSITE
PS01245 RIO1, 1 hit
PS50002 SH3, 1 hit

Sequencei

Sequence statusi: Complete.

A0A091DNS1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDYRRLLMSR VVPGQFDDAE SSDSENTDLK TVKAEDDILF EDLQNSVTEK
60 70 80 90 100
KGEGEIEEEE EEEDYDNDDD WDWDDGVGKL TKGCAWSGVS SPQPEYKSGR
110 120 130 140 150
YNIPQMPDSM DLLAKAAKKL RTLSNHLSEE LAVDVYDEAN RQTSNCSAAK
160 170 180 190 200
MSTPADKVLR KFENKINLDK LNVTDSVMNK VTEKSRQKEA DMYRIKDKAD
210 220 230 240 250
RATVEQVLDP RTRMILFKLL TRGIISEING CISTGKEANV YHASTANGES
260 270 280 290 300
RAIKIYKTSI LVFKDRDKYV SGEFRFRHGY CKGNPRKMVK TWAEKEMRNL
310 320 330 340 350
TRLNTAEIPC PKPIMLRSHV LVMGFIGKDD MPAPLLKNVQ LSESKARELY
360 370 380 390 400
LQVIQYMRRM YQDARLVHAD LSEFNMLYHG GGVHIIDVSQ SVEHDHPHAL
410 420 430 440 450
EFLRKDCANV NDFFMKHAVA VMTVRELFEF VTDPSITPEN VDAYLSKAME
460 470 480 490 500
IASQRTKEER SSQDHVDEEV FKRAYIPRTL NEVKNYERDM AVMMKLKEED
510 520 530 540 550
MAMNAQRDDI LYQTVTGLKK DLSGVQKVPA LLENEDQEKT CSDSEDAGSS
560 570 580 590 600
AHSDTDPEEQ GAQARGQKHT TEPDVDRKVG QVRGLGPVRL RCPSWGSRLR
610 620 630 640 650
GRPQPQLLCG GVPHACVHTS GCVRPLTADK EVEEQTVDCK CNNEQMCWEK
660 670 680 690 700
YIKTNTRQRT METVDSRQDG RVADAVVESK PYSSWTRASQ MGTMSRLQNQ
710 720 730 740 750
NTIQELLQNC ADCLMRAELI VQPELKYGDG IQLSRSRELD ECFAQANDQM
760 770 780 790 800
EVTDSLIREM RHMGQPCDAY QKRLLQLQEQ MRALYKAISV PRVRRASSKG
810 820 830 840 850
GGGYTCQSGS GWDEFTKRMT SECLGWMRQH RAEMDMVAWG VDLASVEQHI
860 870 880 890 900
NSHRGLHNAI GDYRWQLDKI KADLREKSAI YQLEEEYENL LKASFERMDH
910 920 930 940 950
LRQLQNIIQA TSREIMWIND CEEEELLYDW SDRNTDIAQK QEAFSIRMSQ
960 970 980 990 1000
LEVKEKELNK LKQESDQLVL NQHPASDKIE AYMDTLQTQW SWILQITKCI
1010 1020 1030 1040 1050
DVHLKENAAY FQFFEEAQST EAYLKGLQDS IRKKYPCDKN MPLQHLLEQI
1060 1070 1080 1090 1100
KELEKEREKI LEYKRQVQNL VNKSKKIIQL KPRNPDYRSN KPIILRALCD
1110 1120 1130 1140 1150
YKQDQKIVHK GDECILKDNN ERSKWYVTGP GGVDMLVPSV GLIIPPPNPL
1160 1170 1180 1190 1200
AVDLSCKIEQ YYEAILALWN QLYINMKSLV SWHYCMIDIE KIRAMTIAKL
1210 1220 1230 1240 1250
KTMRQEDYMK TISDLELHYQ EFIRNSQGSE MFGDDDKRRM QSQFTDAQKH
1260 1270 1280 1290 1300
YQTLVIQLPG HPQHQTVTKT EITHVGSCQD ANHNKMIETN RENDKQETWL
1310 1320 1330 1340 1350
LMELQKVRRQ IEHCEGRMTL KNLLLTDQPS THHITVKINE LKSVQNDSQA
1360 1370 1380 1390 1400
LAEVLNQLKD VLANFRGSEK YCYLQNELFG LFQKLENING VTDGYLNSLC
1410 1420 1430 1440 1450
PVRSLLQAIL QTEDMLKVYE ARLTEEETVC LDLDKVEAYR CGLKKIKNDL
1460 1470 1480 1490 1500
NLKKSLLATM KAELQKAQQI HCQTSQQYPL YDLDLGKFND KVIQLTDRWQ
1510 1520 1530 1540 1550
KIDKQIDYRL WDLEKQIKQL RNYRDNYQNF CKWLYDAKRR QDSLESMKFG
1560 1570 1580 1590 1600
DSNTVMRFLT EQKNLHNEIS GKRDKSEEVQ KIAELCANSI KDYELQLASY
1610 1620 1630 1640 1650
TSGLETLLNI PIKRTMVQSP SGVILQEAAD MHARYIELLT RSGDYYRFLS
1660 1670 1680 1690 1700
EMLKSLEDLK LKNTKIEVLE EELRLARDAN SENCNKNKFL DQNLQKYQAE
1710 1720 1730 1740 1750
CSQFKAKLSS LEELKRQAEL DGKSAKQNLD KCYAQIKELN EKITRLTYEI
1760 1770 1780 1790 1800
EDEKRRRKSV EDRFDQQKSD YDQLQKARQC EKESLGWQKL ESEKAVKEKE
1810 1820 1830 1840 1850
YEIERLKVLL QEEGARKREY ENELAKVRNH YNEEMSNLRN KYETEINITK
1860 1870 1880 1890 1900
TTIKEISMQK EDDSKSLRNQ LDRLSRENRD LKDEIVRLND SILQATEQRR
1910 1920 1930 1940 1950
RAEENALQQK ACGSEIMQKK QHLEIELKQV IQQRSEDNAR HKHSLEEAAK
1960 1970 1980 1990 2000
TIQDKNKEIE RLKAEFQEEA KRRWEYENEL SKVRNSYDEE IISLRNQFET
2010 2020 2030 2040 2050
EINITKTTIH QLTMQKEEDT SGYRAQIDNL TRENRSLCEE IKRLKNTLAQ
2060 2070 2080 2090 2100
TTENLKRVEE NIQQQKATGS EMSQRKQQLE IELRQVTQMR TEESTRYKQS
2110 2120 2130 2140 2150
LDDAAKTIQD KNREIERLKQ LVEKETSERK CLEDENARLE RVQYDLQKAN
2160 2170 2180 2190 2200
SSATEAISKL KSQEQELTRL RIDYERVSQE RTVKDQDIAR FQSSLKELQL
2210 2220 2230 2240 2250
QKQKVEEELS RLKRTACEDS SKRKKLEEEL DCMRRSLKEQ AIKITSLTQQ
2260 2270 2280 2290 2300
LEQVSIVKKK SEDDLRQQRD VLDGHLRDKQ RTQEDLRRLS SEVEVLRRQL
2310 2320 2330 2340 2350
LQEQENVKQA HLRNEHFQKA IEDKSRSLNE SKIEIERLQS LTENLTKEHL
2360 2370 2380 2390 2400
MLEEELRNLR LEYDDLRRGR SEEENDKSAT ICELRNQLQI SNNRTLELQG
2410 2420 2430 2440 2450
LINDLQRERE NLRQEIEKFQ KQALEASNRI HESKSQCTQV VQERESLLVK
2460 2470 2480 2490 2500
IKVLEQDKVR LQRLEEELNR LKATLEAEGR VKQRLESEKQ QIQNDLNQWK
2510 2520 2530 2540 2550
TQYSRKEEAI RKIESDREKS EREKNSLRSE IERLQAEIKR IEERCRRKLE
2560 2570 2580 2590 2600
DSSRETQSQL ETERSRLQRE FDKLKQRPYG SHRETQTEYE WTVDSSKLVF
2610 2620 2630 2640 2650
DGLRKKVTAM QLYECQLIDK TTLDKLLKGK KSVEEVAAEI QPFLRGAGAI
2660 2670 2680 2690 2700
AGASASPKEK YSLVEAKRKK FITPESTVML LEAQAATGGI IDPHRNEKLT
2710 2720 2730 2740 2750
VDNAIARDLI DFDDRQQIYT AEKAITGFDD PFSGKTVSVS EAIKKNLIDR
2760 2770 2780 2790 2800
ETGMRLLEAQ LASGGIVDPV NSVFLPKDVA LARGLIDRDL YRSLNDPRDS
2810 2820 2830 2840 2850
QKNFVDPFTK KKVSYVQLRE RCRIEPHTGL LLLSVQKRSM SFQGIRQPVT
2860 2870 2880 2890 2900
VTELVDSGIL RPSTVNELES GQISYDEVGE RIKDFLQGSS CIAGIYNETT
2910 2920 2930 2940 2950
KQKLGIYEAM KIGLVRPGTA LELLEAQAAT GFIVDPVSNL RLPVEEAYKR
2960 2970 2980 2990 3000
GLVGIEFKEK LLSAERAVTG YNDPETGNII SLFQAMNKEL IEKGHGIRLL
3010 3020 3030 3040 3050
EAQIATGGII DPKESHRLPV NIAYKRGYFN EELSEILTDP SDDTKGFFDP
3060 3070 3080 3090 3100
NTEENLTYLQ LKERCIKDEE TGLCLLPLKE KKKQVQTSQK NTLRKRRVVI
3110 3120 3130 3140 3150
VDPETNKEMS VQEAYKKGLI DYETFKELCE QECEWEEITI TGSDGSTRVV
3160 3170 3180 3190 3200
LVDRKTGSQY DIQDAIDKGL VDKKFFEQYR SGSLSLTQFA DMISLKNGVG
3210 3220 3230 3240 3250
GSISMGSGVS DDVFSSSRHE SVSKISTISS VRNLTIRSSS LSDPLEESSP
3260 3270 3280 3290 3300
IAAIFDTENL EKISVSEAID RGIVDSITGQ RLLEAQACTG GIIHPTTGQK
3310 3320 3330 3340 3350
LSLQDAVAQG LIDTDMATRL KPAQKAFIGF EGVKGKKKMS AAEAVKEKWL
3360 3370 3380 3390 3400
PYEAGQRFLE FQFLTGGLVD PEVHGRISTE EAIRKGFIDG RAAQRLQDTS
3410 3420 3430 3440 3450
SYAKILTCPK TKLKISYKDA MNRSMVEDVT GLRLLEAASV SSKGLPSPYN
3460 3470 3480 3490 3500
MSSAPGSRSG SRSGSRSGSR SGSRSGSRRG SFDATGNSSY SYSYTFSSSS

IGH
Length:3,503
Mass (Da):404,077
Last modified:November 26, 2014 - v1
Checksum:i5DDE76F7A145D08E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KN122054 Genomic DNA Translation: KFO33769.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KN122054 Genomic DNA Translation: KFO33769.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.90.1290.10, 3 hits
InterProiView protein in InterPro
IPR028462 Desmoplakin
IPR011009 Kinase-like_dom_sf
IPR035915 Plakin_repeat_sf
IPR001101 Plectin_repeat
IPR000687 RIO_kinase
IPR018935 RIO_kinase_CS
IPR001452 SH3_domain
IPR018159 Spectrin/alpha-actinin
PANTHERiPTHR44773 PTHR44773, 1 hit
PfamiView protein in Pfam
PF00681 Plectin, 8 hits
SMARTiView protein in SMART
SM00250 PLEC, 18 hits
SM00090 RIO, 1 hit
SM00150 SPEC, 3 hits
SUPFAMiSSF56112 SSF56112, 1 hit
SSF75399 SSF75399, 5 hits
PROSITEiView protein in PROSITE
PS01245 RIO1, 1 hit
PS50002 SH3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A091DNS1_FUKDA
AccessioniPrimary (citable) accession number: A0A091DNS1
Entry historyiIntegrated into UniProtKB/TrEMBL: November 26, 2014
Last sequence update: November 26, 2014
Last modified: September 12, 2018
This is version 19 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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