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Protein
Submitted name:

Adenylate cyclase type 9

Gene

H920_13789

Organism
Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotation
LigandNucleotide-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Adenylate cyclase type 9Imported
Gene namesi
ORF Names:H920_13789Imported
OrganismiFukomys damarensis (Damaraland mole rat) (Cryptomys damarensis)Imported
Taxonomic identifieri885580 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaHystricomorphaBathyergidaeFukomys
Proteomesi
  • UP000028990 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei116 – 136HelicalSequence analysisAdd BLAST21
Transmembranei142 – 164HelicalSequence analysisAdd BLAST23
Transmembranei176 – 196HelicalSequence analysisAdd BLAST21
Transmembranei242 – 261HelicalSequence analysisAdd BLAST20
Transmembranei788 – 809HelicalSequence analysisAdd BLAST22
Transmembranei821 – 845HelicalSequence analysisAdd BLAST25
Transmembranei866 – 886HelicalSequence analysisAdd BLAST21
Transmembranei892 – 910HelicalSequence analysisAdd BLAST19
Transmembranei977 – 996HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini394 – 521Guanylate cyclaseInterPro annotationAdd BLAST128
Domaini1058 – 1198Guanylate cyclaseInterPro annotationAdd BLAST141

Sequence similaritiesi

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

Gene3Di3.30.70.1230, 2 hits
InterProiView protein in InterPro
IPR001054 A/G_cyclase
IPR018297 A/G_cyclase_CS
IPR029787 Nucleotide_cyclase
PfamiView protein in Pfam
PF00211 Guanylate_cyc, 2 hits
SMARTiView protein in SMART
SM00044 CYCc, 2 hits
SUPFAMiSSF55073 SSF55073, 2 hits
PROSITEiView protein in PROSITE
PS00452 GUANYLATE_CYCLASE_1, 2 hits
PS50125 GUANYLATE_CYCLASE_2, 2 hits

Sequencei

Sequence statusi: Complete.

A0A091D2Q8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASPPHQQLL HHHSTEVSCD SSGDSNSVRV KINPKQLSSN SHPKHCKYSI
60 70 80 90 100
SSSCSSSGDS GGLPRRVGGR SRLRRQRKLP QLFERASSRW WDPKFDSVNL
110 120 130 140 150
EEACLERCFP QTQRRFRYAL FYVGFACLLW SIYFAVHMRS KMIVMVAPPL
160 170 180 190 200
CFLVVCLGFF LFTFTKLYTR HYAWTSLALT LLVFTLTLAV QFQVLTPLSG
210 220 230 240 250
RVDSSNHTPT ARPTDICLSQ VGSFSMCVEV LCLLYTVMHL PLYLSLFLGV
260 270 280 290 300
AYSVLFETFG YHFRDEDCFP SLEARALPWE LLSRALLHVC IHAIGIHLFV
310 320 330 340 350
MSQVRSRSTF LKVGQSIMHG KDLEVEKALK ERMIHSVMPR IIADDLMKQG
360 370 380 390 400
DEESENSVKR HATSSPKNRK KKSSIQKAPI AFRPFKMQQI EEVSILFADI
410 420 430 440 450
VGFTKMSANK SAHALVGLLN DLFGRFDRLC EETKCEKIST LGDCYYCVAG
460 470 480 490 500
CPEPRADHAY CCIEMGLGMI KAIEQFCQEK KEMVNMRVGV HTGTVLCGIL
510 520 530 540 550
GMRRFKFDVW SNDVNLANLM EQLGVAGKVH ISEATAKYLD DRYEMEDGKV
560 570 580 590 600
IERLGQSVVA DQLKGLKTYL ISGQRAKESH CSCAEALLSG FEAIDGSRVS
610 620 630 640 650
SGPRGQGTAS SGSVSDLAQT VKTFDNLKTC PSCGITFAPK SEAGAEGGAV
660 670 680 690 700
QNGCQDETKT STKASGGPNS KAQNGLLSPP KEEKLTNSQT SLCEILQEKG
710 720 730 740 750
RWTGVSLDQS ALLPLRFKNI REKTDAHFVD VIKEDSLMKD YFFKPPINQF
760 770 780 790 800
SLNFLDQELE RSYRTSYQEE VIKNSPVKTF ASATFSSLLD VLLSTTVFLI
810 820 830 840 850
LSVTCFLKYG ATAMPPPPAA LAIFGAALLL EVLSLVVSIR MVFFLEDVMA
860 870 880 890 900
CTQRLLEWIA GWLPRHCIGA VLVSLPALAV YSHITFEFET NVHFTVFISS
910 920 930 940 950
AVLVAVVHYC NFCQLSSWMR SSLATIVGAG PLLLLYVSLC PDSSIVISPL
960 970 980 990 1000
DVARNFSAER NPCNSSLTQD SRRPTSLVGE ELILSFFLLL LLVWFLNREF
1010 1020 1030 1040 1050
EVSYRLHYHG DVEADLHRTK IQSMRDQADW LLRNIIPYHV AEQLKVSQTY
1060 1070 1080 1090 1100
SKNHDSGGVI FASIVNFSEF YEENYEGGKE CYRVLNELIG DFDELLSKPD
1110 1120 1130 1140 1150
YSSIEKIKTI GATYMAASGL NTAQCQEGSH PQEHLRILFE FAREMMHVVD
1160 1170 1180 1190 1200
DFNNNMLWFN FKLRVGFNHG PLTAGVIGTT KLLYDIWGDT VNIASRMDTT
1210 1220 1230 1240 1250
GVECRIQVSE ESYRVLSKMG YDFDYRGTVN VKGKGQMKTY LYPKCVDNGV
1260 1270 1280 1290 1300
VPQHQLSISP DIRVQVDGSI GRSPTDEIAN LVPSVQYSDK TSLGSDDNTQ
1310 1320 1330 1340 1350
AKDAHLSSKR PWKEPIKVEE RCRFGKAIEK DDCEEMGMEE ANELTKLNIS

KSV
Length:1,353
Mass (Da):151,414
Last modified:November 26, 2014 - v1
Checksum:i40121DEEB148A004
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KN123497 Genomic DNA Translation: KFO24793.1
RefSeqiXP_010642369.1, XM_010644067.1

Genome annotation databases

EnsembliENSFDAT00000009171; ENSFDAP00000023003; ENSFDAG00000021257
GeneIDi104876168

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KN123497 Genomic DNA Translation: KFO24793.1
RefSeqiXP_010642369.1, XM_010644067.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSFDAT00000009171; ENSFDAP00000023003; ENSFDAG00000021257
GeneIDi104876168

Organism-specific databases

CTDi115

Family and domain databases

Gene3Di3.30.70.1230, 2 hits
InterProiView protein in InterPro
IPR001054 A/G_cyclase
IPR018297 A/G_cyclase_CS
IPR029787 Nucleotide_cyclase
PfamiView protein in Pfam
PF00211 Guanylate_cyc, 2 hits
SMARTiView protein in SMART
SM00044 CYCc, 2 hits
SUPFAMiSSF55073 SSF55073, 2 hits
PROSITEiView protein in PROSITE
PS00452 GUANYLATE_CYCLASE_1, 2 hits
PS50125 GUANYLATE_CYCLASE_2, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A091D2Q8_FUKDA
AccessioniPrimary (citable) accession number: A0A091D2Q8
Entry historyiIntegrated into UniProtKB/TrEMBL: November 26, 2014
Last sequence update: November 26, 2014
Last modified: July 18, 2018
This is version 18 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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