ABCF2

Functionⁱ

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Nucleotide bindingⁱ	118 – 125	ATPPROSITE-ProRule annotation		8
Nucleotide bindingⁱ	430 – 437	ATPPROSITE-ProRule annotation		8

GO - Molecular functionⁱ

ATPase activity Source: InterPro
ATP binding Source: UniProtKB-UniRule

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Ligand	ATP-bindingPROSITE-ProRule annotationImported, Nucleotide-binding

Ligand

ATP-bindingPROSITE-ProRule annotationImported, Nucleotide-binding

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: ATP-binding cassette, sub-family F (GCN20), member 2Imported
Gene namesⁱ	Name:ABCF2Imported ORF Names:tcag7.790Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000033050.7

EuPathDBⁱ

HostDB:ENSG00000033050.7

PTM / Processingⁱ

Proteomic databases

PRIDEⁱ	A0A090N7X1

PRIDEⁱ

A0A090N7X1

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000033050 Expressed in 219 organ(s), highest expression level in oocyte
ExpressionAtlasⁱ	A0A090N7X1 baseline and differential

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	A0A090N7X1
SMRⁱ	A0A090N7X1
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	86 – 325	ABC transporterInterPro annotationAdd BLAST		240
Domainⁱ	396 – 613	ABC transporterInterPro annotationAdd BLAST		218

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	53 – 73	Sequence analysisAdd BLAST		21
Coiled coilⁱ	162 – 209	Sequence analysisAdd BLAST		48

Keywords - Domainⁱ

Coiled coilSequence analysis

Phylogenomic databases

eggNOGⁱ	KOG0927 Eukaryota COG0488 LUCA
KEGG Orthology (KO) More...KOⁱ	K06185
PhylomeDBⁱ	A0A090N7X1

Family and domain databases

InterProⁱ	View protein in InterPro IPR003593 AAA+_ATPase IPR032781 ABC_tran_Xtn IPR003439 ABC_transporter-like IPR017871 ABC_transporter_CS IPR027417 P-loop_NTPase
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00005 ABC_tran, 2 hits PF12848 ABC_tran_Xtn, 1 hit
SMARTⁱ	View protein in SMART SM00382 AAA, 2 hits
SUPFAMⁱ	SSF52540 SSF52540, 2 hits
PROSITEⁱ	View protein in PROSITE PS00211 ABC_TRANSPORTER_1, 1 hit PS50893 ABC_TRANSPORTER_2, 2 hits

Sequenceⁱ

Sequence statusⁱ: Complete.

A0A090N7X1-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MPSDLAKKKA AKKKEAAKAR QRPRKGHEEN GDVVTEPQVA EKNEANGRET 
        60         70         80         90        100
TEVDLLTKEL EDFEMKKAAA RAVTGVLASH PNSTDVHIIN LSLTFHGQEL 
       110        120        130        140        150
LSDTKLELNS GRRYGLIGLN GIGKSMLLSA IGKREVPIPE HIDIYHLTRE 
       160        170        180        190        200
MPPSDKTPLH CVMEVDTERA MLEKEAERLA HEDAECEKLM ELYERLEELD 
       210        220        230        240        250
ADKAEMRASR ILHGLGFTPA MQRKKLKDFS GGWRMRVALA RALFIRPFML 
       260        270        280        290        300
LLDEPTNHLD LDACVWLEEE LKTFKRILVL VSHSQDFLNG VCTNIIHMHN 
       310        320        330        340        350
KKLKYYTGNY DQYVKTRLEL EENQMKRFHW EQDQIAHMKN YIARFGHGSA 
       360        370        380        390        400
KLARQAQSKE KTLQKMMASG LTERVVSDKT LSFYFPPCGK IPPPVIMVQN 
       410        420        430        440        450
VSFKYTKDGP CIYNNLEFGI DLDTRVALVG PNGAGKSTLL KLLTGELLPT 
       460        470        480        490        500
DGMIRKHSHV KIGRYHQHLQ EQLDLDLSPL EYMMKCYPEI KEKEEMRKII 
       510        520        530        540        550
GRYGLTGKQQ VSPIRNLSDG QKCRVCLAWL AWQNPHMLFL DEPTNHLDIE 
       560        570        580        590        600
TIDALADAIN EFEGGMMLVS HDFRLIQQVA QEIWVCEKQT ITKWPGDILA 
       610        620 
YKEHLKSKLV DEEPQLTKRT HNV

Length:623

Mass (Da):71,290

Last modified:November 26, 2014 - v1

Checksum:ⁱ702A968BCF8061AE

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AACC02000108 Genomic DNA Translation: EAL24508.1
NCBI Reference Sequences More...RefSeqⁱ	NP_009120.1, NM_007189.2 XP_016867128.1, XM_017011639.1 XP_016867129.1, XM_017011640.1
UniGeneⁱ	Hs.654958

Genome annotation databases

GeneIDⁱ	10061
KEGGⁱ	hsa:10061

Protein	Similar proteins		Species	Score	Length	Source
A0A090N7X1	ATP-binding cassette sub-family F member 2		HUMAN		623	UniRef100_Q9UG63
ABCF2 isoform 2		PANTR		623
Uncharacterized protein		PANPA		623
ATP-binding cassette, sub-family F (GCN20), member 2		HUMAN		634
Isoform 2 of ATP-binding cassette sub-family F member 2		HUMAN		634
+4

Protein	Similar proteins		Species	Score	Length	Source
A0A090N7X1	ATP-binding cassette sub-family F member 2		HUMAN		623	UniRef90_Q9UG63
ATP-binding cassette sub-family F member 2		MOUSE		628
ATP-binding cassette sub-family F member 2		BOVIN		625
ABCF2 isoform 2		PANTR		623
Uncharacterized protein		PANPA		623
+109

Protein	Similar proteins		Species	Score	Length	Source
A0A090N7X1	ATP-binding cassette sub-family F member 2		HUMAN		623	UniRef50_Q9UG63
ATP-binding cassette sub-family F member 2		MOUSE		628
ATP-binding cassette sub-family F member 2		BOVIN		625
ABC transporter F family member 1		ARATH		595
ABCF2 isoform 2		PANTR		623
+619

Entry informationⁱ

Entry nameⁱ	A0A090N7X1_HUMAN
Accessionⁱ	A0A090N7X1Primary (citable) accession number: A0A090N7X1
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	November 26, 2014
	Last sequence update:	November 26, 2014
	Last modified:	September 12, 2018
	This is version 30 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

UniProtKB - A0A090N7X1 (A0A090N7X1_HUMAN)

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ATP-binding cassette, sub-family F (GCN20), member 2

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Functionⁱ

Caution

Regions

GO - Molecular functionⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Organism-specific databases

PTM / Processingⁱ

Proteomic databases

Expressionⁱ

Gene expression databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Coiled coil

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Entry informationⁱ

UniProt is an ELIXIR core data resource

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Proteomes

Annotation systems

Supporting data

UniProtKB - A0A090N7X1 (A0A090N7X1_HUMAN)

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ATP-binding cassette, sub-family F (GCN20), member 2

ABCF2

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

UniProt is an ELIXIR core data resource

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Entry informationⁱ