UniProtKB - A0A090N7X1 (A0A090N7X1_HUMAN)
Protein
Submitted name:
ATP-binding cassette, sub-family F (GCN20), member 2
Gene
ABCF2
Organism
Homo sapiens (Human)
Status
Functioni
Caution
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 118 – 125 | ATPPROSITE-ProRule annotation | 8 | |
Nucleotide bindingi | 430 – 437 | ATPPROSITE-ProRule annotation | 8 |
GO - Molecular functioni
- ATPase activity Source: InterPro
- ATP binding Source: UniProtKB-UniRule
Keywordsi
Ligand | ATP-bindingPROSITE-ProRule annotationImportedARBA annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Submitted name: ATP-binding cassette, sub-family F (GCN20), member 2Imported |
Gene namesi | Name:ABCF2Imported ORF Names:tcag7.790Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000033050.7 |
Expressioni
Gene expression databases
Bgeei | ENSG00000033050, Expressed in oocyte and 231 other tissues |
ExpressionAtlasi | A0A090N7X1, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 86 – 325 | ABC transporterInterPro annotationAdd BLAST | 240 | |
Domaini | 396 – 613 | ABC transporterInterPro annotationAdd BLAST | 218 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 51 | DisorderedSequence analysisAdd BLAST | 51 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 53 – 73 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 162 – 209 | Sequence analysisAdd BLAST | 48 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 21 – 35 | PolyampholyteSequence analysisAdd BLAST | 15 |
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
HOGENOMi | CLU_000604_36_6_1 |
PhylomeDBi | A0A090N7X1 |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR032781, ABC_tran_Xtn IPR003439, ABC_transporter-like IPR017871, ABC_transporter_CS IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00005, ABC_tran, 2 hits PF12848, ABC_tran_Xtn, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 2 hits |
SUPFAMi | SSF52540, SSF52540, 2 hits |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 2 hits |
i Sequence
Sequence statusi: Complete.
A0A090N7X1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPSDLAKKKA AKKKEAAKAR QRPRKGHEEN GDVVTEPQVA EKNEANGRET
60 70 80 90 100
TEVDLLTKEL EDFEMKKAAA RAVTGVLASH PNSTDVHIIN LSLTFHGQEL
110 120 130 140 150
LSDTKLELNS GRRYGLIGLN GIGKSMLLSA IGKREVPIPE HIDIYHLTRE
160 170 180 190 200
MPPSDKTPLH CVMEVDTERA MLEKEAERLA HEDAECEKLM ELYERLEELD
210 220 230 240 250
ADKAEMRASR ILHGLGFTPA MQRKKLKDFS GGWRMRVALA RALFIRPFML
260 270 280 290 300
LLDEPTNHLD LDACVWLEEE LKTFKRILVL VSHSQDFLNG VCTNIIHMHN
310 320 330 340 350
KKLKYYTGNY DQYVKTRLEL EENQMKRFHW EQDQIAHMKN YIARFGHGSA
360 370 380 390 400
KLARQAQSKE KTLQKMMASG LTERVVSDKT LSFYFPPCGK IPPPVIMVQN
410 420 430 440 450
VSFKYTKDGP CIYNNLEFGI DLDTRVALVG PNGAGKSTLL KLLTGELLPT
460 470 480 490 500
DGMIRKHSHV KIGRYHQHLQ EQLDLDLSPL EYMMKCYPEI KEKEEMRKII
510 520 530 540 550
GRYGLTGKQQ VSPIRNLSDG QKCRVCLAWL AWQNPHMLFL DEPTNHLDIE
560 570 580 590 600
TIDALADAIN EFEGGMMLVS HDFRLIQQVA QEIWVCEKQT ITKWPGDILA
610 620
YKEHLKSKLV DEEPQLTKRT HNV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AACC02000108 Genomic DNA Translation: EAL24508.1 |
RefSeqi | NP_009120.1, NM_007189.2 XP_016867128.1, XM_017011639.1 XP_016867129.1, XM_017011640.1 |
Genome annotation databases
GeneIDi | 10061 |
KEGGi | hsa:10061 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AACC02000108 Genomic DNA Translation: EAL24508.1 |
RefSeqi | NP_009120.1, NM_007189.2 XP_016867128.1, XM_017011639.1 XP_016867129.1, XM_017011640.1 |
3D structure databases
SMRi | A0A090N7X1 |
ModBasei | Search... |
Protocols and materials databases
Antibodypediai | 18732, 332 antibodies |
Genome annotation databases
GeneIDi | 10061 |
KEGGi | hsa:10061 |
Organism-specific databases
CTDi | 10061 |
EuPathDBi | HostDB:ENSG00000033050.7 |
Phylogenomic databases
HOGENOMi | CLU_000604_36_6_1 |
PhylomeDBi | A0A090N7X1 |
Miscellaneous databases
BioGRID-ORCSi | 10061, 15 hits in 842 CRISPR screens |
ChiTaRSi | ABCF2, human |
GenomeRNAii | 10061 |
Gene expression databases
Bgeei | ENSG00000033050, Expressed in oocyte and 231 other tissues |
ExpressionAtlasi | A0A090N7X1, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR032781, ABC_tran_Xtn IPR003439, ABC_transporter-like IPR017871, ABC_transporter_CS IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00005, ABC_tran, 2 hits PF12848, ABC_tran_Xtn, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 2 hits |
SUPFAMi | SSF52540, SSF52540, 2 hits |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A090N7X1_HUMAN | |
Accessioni | A0A090N7X1Primary (citable) accession number: A0A090N7X1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 26, 2014 |
Last sequence update: | November 26, 2014 | |
Last modified: | December 2, 2020 | |
This is version 41 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |