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Entry version 62 (29 Sep 2021)
Sequence version 1 (26 Nov 2014)
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Protein

Endoribonuclease SymE

Gene

symE

Organism
Escherichia coli
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in the degradation and recycling of damaged RNA. It is itself a target for degradation by the ATP-dependent protease Lon.

UniRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotation, EndonucleaseUniRule annotationARBA annotation, Hydrolase, Nuclease, RNA-bindingUniRule annotationARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Endoribonuclease SymEUniRule annotation (EC:3.1.-.-UniRule annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:symEUniRule annotationImported
Synonyms:yjiWImported
ORF Names:AM464_16415Imported, AUQ29_02760Imported, B9T59_08810Imported, BE930_15025Imported, BON65_08195Imported, BvCms2454_01451Imported, C6B13_05605Imported, CF32_002201Imported, DAH50_12260Imported, DNQ45_23890Imported, DU321_02425Imported, E4K51_18315Imported, EC3234A_192c00330Imported, ELT17_00025Imported, ELV08_11195Imported, FV293_11535Imported, GF646_13665Imported, GF699_12415Imported, GKE84_17065Imported, GW978_23810Imported, HVY77_22420Imported, WP2S18E08_40550Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coliImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri562 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000249482 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000523473 Componenti: Unassembled WGS sequence
  • UP000439439 Componenti: Unassembled WGS sequence
  • UP000460351 Componenti: Unassembled WGS sequence
  • UP000318266 Componenti: Unassembled WGS sequence
  • UP000512322 Componenti: Chromosome
  • UP000321295 Componenti: Unassembled WGS sequence
  • UP000070294 Componenti: Unassembled WGS sequence
  • UP000246203 Componenti: Chromosome
  • UP000297614 Componenti: Unassembled WGS sequence
  • UP000557797 Componenti: Unassembled WGS sequence
  • UP000298116 Componenti: Unassembled WGS sequence
  • UP000302965 Componenti: Unassembled WGS sequence
  • UP000077380 Componenti: Unassembled WGS sequence
  • UP000272662 Componenti: Unassembled WGS sequence
  • UP000189650 Componenti: Chromosome
  • UP000515421 Componenti: Chromosome
  • UP000570280 Componenti: Unassembled WGS sequence
  • UP000247477 Componenti: Chromosome
  • UP000546337 Componenti: Unassembled WGS sequence
  • UP000252850 Componenti: Unassembled WGS sequence
  • UP000297379 Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

CytoplasmUniRule annotation

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini29 – 74SpoVT-AbrBInterPro annotationAdd BLAST46

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SymE family.UniRule annotation

Family and domain databases

HAMAP database of protein families

More...
HAMAPi
MF_01193, Endoribonucl_SymE, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007159, SpoVT-AbrB_dom
IPR014944, Toxin_SymE-like
IPR020883, TypeI_TA_SymE

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08845, SymE_toxin, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51740, SPOVT_ABRB, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A090KZF8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTDTHSIAQP FEAEVSPANN RHVTVGYASR YPDYSRIPAI TLKGQWLEAA
60 70 80 90 100
GFATGTAVDV KVMEGCIVLT AQPPAAEESE LMQSLRQVCK LSARKQKQVQ
110
AFIGVIAGKQ KVA
Length:113
Mass (Da):12,203
Last modified:November 26, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4C3C0CE696CE7D9D
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP019029 Genomic DNA Translation: AQV68101.1
CP021193 Genomic DNA Translation: AWR81223.1
CP029741 Genomic DNA Translation: AWS64301.1
AP021946 Genomic DNA Translation: BBQ64072.1
AASVHW010000111 Genomic DNA Translation: EFH2600648.1
AATJQR010000010 Genomic DNA Translation: EFM0579088.1
BFGA01000023 Genomic DNA Translation: GCP01002.1
DABAWC010000016 Genomic DNA Translation: HAH2765448.1
DABAWN010000022 Genomic DNA Translation: HAH2819473.1
LOPO01000004 Genomic DNA Translation: KXR87393.1
SQQU01000026 Genomic DNA Translation: MQS32072.1
WKRN01000416 Genomic DNA Translation: MSL29092.1
LCVH01000192 Genomic DNA Translation: OAC30557.1
QKWZ01000768 Genomic DNA Translation: PZT64232.1
CP057293 Genomic DNA Translation: QMF69407.1
PUSI01000003 Genomic DNA Translation: RCE97592.1
RRVG01000002 Genomic DNA Translation: RRL50749.1
MTWY01000036 Genomic DNA Translation: TEZ15931.1
RZDD01000025 Genomic DNA Translation: TFP39850.1
RZAF01000001 Genomic DNA Translation: TFT31337.1
QAFV01000013 Genomic DNA Translation: TGE95495.1
VRXD01000014 Genomic DNA Translation: TXQ34582.1

NCBI Reference Sequences

More...
RefSeqi
WP_000132601.1, NZ_WVUZ01000013.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AIX66458; AIX66458; ECONIH1_26010
AOM73005; AOM73005; MS6198_51140
AWR81223; AWR81223; B9T59_08810
AWS64301; AWS64301; AM464_16415
AYE18773; AYE18773; Eco118UI_25800
AYZ40616; AYZ40616; EGY17_12920
KNZ99108; KNZ99108; AKG99_10765
KXG88720; KXG88720; HMPREF3040_05564
KXR92239; KXR92239; AUQ13_08695
OAC30557; OAC30557; EC3234A_192c00330
OZX98168; OZX98168; CIJ94_01060
PPI96160; PPI96160; C4J69_04620
PPZ06644; PPZ06644; C5P44_07995
PZT64232; PZT64232; DNQ45_23890
RBV92425; RBV92425; B9M99_13295
RCE97592; RCE97592; C6B13_05605

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|562.10493.peg.1017

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP019029 Genomic DNA Translation: AQV68101.1
CP021193 Genomic DNA Translation: AWR81223.1
CP029741 Genomic DNA Translation: AWS64301.1
AP021946 Genomic DNA Translation: BBQ64072.1
AASVHW010000111 Genomic DNA Translation: EFH2600648.1
AATJQR010000010 Genomic DNA Translation: EFM0579088.1
BFGA01000023 Genomic DNA Translation: GCP01002.1
DABAWC010000016 Genomic DNA Translation: HAH2765448.1
DABAWN010000022 Genomic DNA Translation: HAH2819473.1
LOPO01000004 Genomic DNA Translation: KXR87393.1
SQQU01000026 Genomic DNA Translation: MQS32072.1
WKRN01000416 Genomic DNA Translation: MSL29092.1
LCVH01000192 Genomic DNA Translation: OAC30557.1
QKWZ01000768 Genomic DNA Translation: PZT64232.1
CP057293 Genomic DNA Translation: QMF69407.1
PUSI01000003 Genomic DNA Translation: RCE97592.1
RRVG01000002 Genomic DNA Translation: RRL50749.1
MTWY01000036 Genomic DNA Translation: TEZ15931.1
RZDD01000025 Genomic DNA Translation: TFP39850.1
RZAF01000001 Genomic DNA Translation: TFT31337.1
QAFV01000013 Genomic DNA Translation: TGE95495.1
VRXD01000014 Genomic DNA Translation: TXQ34582.1
RefSeqiWP_000132601.1, NZ_WVUZ01000013.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiAIX66458; AIX66458; ECONIH1_26010
AOM73005; AOM73005; MS6198_51140
AWR81223; AWR81223; B9T59_08810
AWS64301; AWS64301; AM464_16415
AYE18773; AYE18773; Eco118UI_25800
AYZ40616; AYZ40616; EGY17_12920
KNZ99108; KNZ99108; AKG99_10765
KXG88720; KXG88720; HMPREF3040_05564
KXR92239; KXR92239; AUQ13_08695
OAC30557; OAC30557; EC3234A_192c00330
OZX98168; OZX98168; CIJ94_01060
PPI96160; PPI96160; C4J69_04620
PPZ06644; PPZ06644; C5P44_07995
PZT64232; PZT64232; DNQ45_23890
RBV92425; RBV92425; B9M99_13295
RCE97592; RCE97592; C6B13_05605
PATRICifig|562.10493.peg.1017

Family and domain databases

HAMAPiMF_01193, Endoribonucl_SymE, 1 hit
InterProiView protein in InterPro
IPR007159, SpoVT-AbrB_dom
IPR014944, Toxin_SymE-like
IPR020883, TypeI_TA_SymE
PfamiView protein in Pfam
PF08845, SymE_toxin, 1 hit
PROSITEiView protein in PROSITE
PS51740, SPOVT_ABRB, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A090KZF8_ECOLX
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A090KZF8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 26, 2014
Last sequence update: November 26, 2014
Last modified: September 29, 2021
This is version 62 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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