UniProtKB - A0A089QDC1 (A0A089QDC1_HUMAN)
Protein
Submitted name:
Histo-blood group ABO system transferase
Gene
ABO
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- transferase activity, transferring hexosyl groups Source: InterPro
GO - Biological processi
- carbohydrate metabolic process Source: InterPro
Keywordsi
Molecular function | TransferaseImported |
Names & Taxonomyi
Protein namesi | Submitted name: Histo-blood group ABO system transferaseImported |
Gene namesi | Name:ABOImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Single-pass type II membrane protein ARBA annotation
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 20 – 37 | HelicalSequence analysisAdd BLAST | 18 |
Keywords - Cellular componenti
MembraneFamily & Domainsi
Sequence similaritiesi
Belongs to the glycosyltransferase 6 family.ARBA annotation
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
OrthoDBi | 1204439at2759 |
PhylomeDBi | A0A089QDC1 |
Family and domain databases
Gene3Di | 3.90.550.10, 1 hit |
InterProi | View protein in InterPro IPR005076, Glyco_trans_6 IPR029044, Nucleotide-diphossugar_trans |
PANTHERi | PTHR10462, PTHR10462, 1 hit |
Pfami | View protein in Pfam PF03414, Glyco_transf_6, 1 hit |
SUPFAMi | SSF53448, SSF53448, 1 hit |
i Sequence
Sequence statusi: Complete.
A0A089QDC1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAEVLRTLAG KPKCHALRPM ILFLIMLVLV LFGYGVLSPR SLMPGSLERG
60 70 80 90 100
FCMAVREPDH LQRVSLPRMV YPQPKVLTPC RKDVLVVTPW LAPIVWEGTF
110 120 130 140 150
NIDILNEQFR LQNTTIGLTV FAIKKYVAFL KLFLETAEKH FMVGHRVHYY
160 170 180 190 200
VFTDQPAAVP RVTLGTGRQL SVLEVRAYKR WQDVSMRRME MISDFCERRF
210 220 230 240 250
LSEVDYLVCV DVDMEFRDHV GVEILTPLFG TLHPGFYGSS REAFTYERRP
260 270 280 290 300
QSQAYIPKDE GDFYYLGGFF GGSVQEVQRL TRACHQAMMV DQANGIEAVW
310 320 330 340 350
HDESHLNKYL LRHKPTKVLS PEYLWDQQLL GWPAVLRKLR FTAVPKNHQA
VRNP
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | KM068114 Genomic DNA Translation: AIR08539.1 |
RefSeqi | NP_065202.2, NM_020469.2 |
Genome annotation databases
GeneIDi | 28 |
KEGGi | hsa:28 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | KM068114 Genomic DNA Translation: AIR08539.1 |
RefSeqi | NP_065202.2, NM_020469.2 |
3D structure databases
SMRi | A0A089QDC1 |
ModBasei | Search... |
Chemistry databases
BindingDBi | A0A089QDC1 |
Genome annotation databases
GeneIDi | 28 |
KEGGi | hsa:28 |
Organism-specific databases
CTDi | 28 |
Phylogenomic databases
OrthoDBi | 1204439at2759 |
PhylomeDBi | A0A089QDC1 |
Miscellaneous databases
BioGRID-ORCSi | 28, 1 hit in 96 CRISPR screens |
ChiTaRSi | ABO, human |
GenomeRNAii | 28 |
Family and domain databases
Gene3Di | 3.90.550.10, 1 hit |
InterProi | View protein in InterPro IPR005076, Glyco_trans_6 IPR029044, Nucleotide-diphossugar_trans |
PANTHERi | PTHR10462, PTHR10462, 1 hit |
Pfami | View protein in Pfam PF03414, Glyco_transf_6, 1 hit |
SUPFAMi | SSF53448, SSF53448, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A089QDC1_HUMAN | |
Accessioni | A0A089QDC1Primary (citable) accession number: A0A089QDC1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 26, 2014 |
Last sequence update: | November 26, 2014 | |
Last modified: | February 10, 2021 | |
This is version 24 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |