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Entry version 44 (31 Jul 2019)
Sequence version 1 (29 Oct 2014)
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Protein
Submitted name:

Nuclear receptor corepressor 1

Gene

NCOR1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Nuclear receptor corepressor 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NCOR1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:7672 NCOR1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

NucleusSAAS annotation

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000141027

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
A0A088AWL3

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
A0A088AWL3

PeptideAtlas

More...
PeptideAtlasi
A0A088AWL3

PRoteomics IDEntifications database

More...
PRIDEi
A0A088AWL3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000141027 Expressed in 227 organ(s), highest expression level in corpus callosum

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A0A088AWL3 baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini326 – 377SANTInterPro annotationAdd BLAST52
Domaini514 – 565SANTInterPro annotationAdd BLAST52

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 74DisorderedSequence analysisAdd BLAST74
Regioni97 – 122DisorderedSequence analysisAdd BLAST26
Regioni388 – 524DisorderedSequence analysisAdd BLAST137
Regioni568 – 822DisorderedSequence analysisAdd BLAST255
Regioni929 – 953DisorderedSequence analysisAdd BLAST25
Regioni1091 – 1111DisorderedSequence analysisAdd BLAST21
Regioni1347 – 1366DisorderedSequence analysisAdd BLAST20
Regioni1395 – 1442DisorderedSequence analysisAdd BLAST48
Regioni1594 – 1663DisorderedSequence analysisAdd BLAST70
Regioni1788 – 1826DisorderedSequence analysisAdd BLAST39
Regioni1847 – 1873DisorderedSequence analysisAdd BLAST27
Regioni1910 – 1945DisorderedSequence analysisAdd BLAST36
Regioni1971 – 2059DisorderedSequence analysisAdd BLAST89
Regioni2191 – 2343DisorderedSequence analysisAdd BLAST153

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili199 – 219Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 35PolarSequence analysisAdd BLAST35
Compositional biasi53 – 70PolarSequence analysisAdd BLAST18
Compositional biasi395 – 461PolyampholyteSequence analysisAdd BLAST67
Compositional biasi496 – 511Pro-richSequence analysisAdd BLAST16
Compositional biasi568 – 589PolyampholyteSequence analysisAdd BLAST22
Compositional biasi603 – 622AcidicSequence analysisAdd BLAST20
Compositional biasi643 – 702PolarSequence analysisAdd BLAST60
Compositional biasi730 – 766PolyampholyteSequence analysisAdd BLAST37
Compositional biasi774 – 791PolarSequence analysisAdd BLAST18
Compositional biasi1395 – 1434PolarSequence analysisAdd BLAST40
Compositional biasi1613 – 1636PolyampholyteSequence analysisAdd BLAST24
Compositional biasi1811 – 1826PolyampholyteSequence analysisAdd BLAST16
Compositional biasi1857 – 1871PolarSequence analysisAdd BLAST15
Compositional biasi1924 – 1944PolarSequence analysisAdd BLAST21
Compositional biasi1971 – 2020PolarSequence analysisAdd BLAST50
Compositional biasi2032 – 2046PolyampholyteSequence analysisAdd BLAST15
Compositional biasi2250 – 2264PolarSequence analysisAdd BLAST15
Compositional biasi2274 – 2319PolarSequence analysisAdd BLAST46

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1878 Eukaryota
ENOG410YDXP LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155093

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00167 SANT, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009057 Homeobox-like_sf
IPR031557 N-CoR_GPS2_interact
IPR001005 SANT/Myb
IPR017884 SANT_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15784 GPS2_interact, 1 hit
PF00249 Myb_DNA-binding, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00717 SANT, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46689 SSF46689, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51293 SANT, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 12 potential isoforms that are computationally mapped.Show allAlign All

A0A088AWL3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSSGYPPNQ GAFSTEQSRY PPHSVQYTFP NTRHQQDPAF GGKHEAPSSP
60 70 80 90 100
ISGQPCGDDQ NASPSKLSKE ELIQSMDRVD REIAKVEQQI LKLKKKQQQL
110 120 130 140 150
EEEAAKPPEP EKPVSPPPVE QKHRSIVQII YDENRKKAEE AHKIFEGLGP
160 170 180 190 200
KVELPLYNQP SDTKVYHENI KTNQVMRKKL ILFFKRRNHA RKQREQKICQ
210 220 230 240 250
RYDQLMEAWE KKVDRIENNP RRKAKESKTR EYYEKQFPEI RKQREQQERF
260 270 280 290 300
QRVGQRGAGL SATIARSEHE ISEIIDGLSE QENNEKQMRQ LSVIPPMMFD
310 320 330 340 350
AEQRRVKFIN MNGLMEDPMK VYKDRQFMNV WTDHEKEIFK DKFIQHPKNF
360 370 380 390 400
GLIASYLERK SVPDCVLYYY LTKKNENYKA LVRRNYGKRR GRNQQIARPS
410 420 430 440 450
QEEKVEEKEE DKAEKTEKKE EEKKDEEEKD EKEDSKENTK EKDKIDGTAE
460 470 480 490 500
ETEEREQATP RGRKTANSQG RRKGRITRSM TNEAAAASAA AAAATEEPPP
510 520 530 540 550
PLPPPPEPIS TEPVETSRWT EEEMEVAKKG LVEHGRNWAA IAKMVGTKSE
560 570 580 590 600
AQCKNFYFNY KRRHNLDNLL QQHKQKTSRK PREERDVSQC ESVASTVSAQ
610 620 630 640 650
EDEDIEASNE EENPEDSEGA ENSSDTESAP SPSPVEAVKP SEDSPENATS
660 670 680 690 700
RGNTEPAVEL EPTTETAPST SPSLAVPSTK PAEDESVETQ VNDSISAETA
710 720 730 740 750
EQMDVDQQEH SAEEGSVCDP PPATKADSVD VEVRVPENHA SKVEGDNTKE
760 770 780 790 800
RDLDRASEKV EPRDEDLVVA QQINAQRPEP QSDNDSSATC SADEDVDGEP
810 820 830 840 850
ERQRMFPMDS KPSLLNPTGS ILVSSPLKPN PLDLPQLQHR AAVIPPMVSC
860 870 880 890 900
TPCNIPIGTP VSGYALYQRH IKAMHESALL EEQRQRQEQI DLECRSSTSP
910 920 930 940 950
CGTSKSPNRE WEVLQPAPHQ VITNLPEGVR LPTTRPTRPP PPLIPSSKTT
960 970 980 990 1000
VASEKPSFIM GGSISQGTPG TYLTSHNQAS YTQETPKPSV GSISLGLPRQ
1010 1020 1030 1040 1050
QESAKSATLP YIKQEEFSPR SQNSQPEGLL VRAQHEGVVR GTAGAIQEGS
1060 1070 1080 1090 1100
ITRGTPTSKI SVESIPSLRG SITQGTPALP QTGIPTEALV KGSISRMPIE
1110 1120 1130 1140 1150
DSSPEKGREE AASKGHVIYE GKSGHILSYD NIKNAREGTR SPRTAHEISL
1160 1170 1180 1190 1200
KRSYESVEGN IKQGMSMRES PVSAPLEGLI CRALPRGSPH SDLKERTVLS
1210 1220 1230 1240 1250
GSIMQGTPRA TTESFEDGLK YPKQIKRESP PIRAFEGAIT KGKPYDGITT
1260 1270 1280 1290 1300
IKEMGRSIHE IPRQDILTQE SRKTPEVVQS TRPIIEGSIS QGTPIKFDNN
1310 1320 1330 1340 1350
SGQSAIKHNV KSLITGPSKL SRGMPPLEIV PENIKVVERG KYEDVKAGET
1360 1370 1380 1390 1400
VRSRHTSVVS SGPSVLRSTL HEAPKAQLSP GIYDDTSARR TPVSYQNTMS
1410 1420 1430 1440 1450
RGSPMMNRTS DVSSNKSTNH ERKSTLTPTQ RESIPAKSPV PGVDPVVSHS
1460 1470 1480 1490 1500
PFDPHHRGST AGEVYRSHLP THLDPAMPFH RALDPAAAYL FQRQLSPTPG
1510 1520 1530 1540 1550
YPSQYQLYAM ENTRQTILND YITSQQMQVN LRPDVARGLS PREQPLGLPY
1560 1570 1580 1590 1600
PATRGIIDLT NMPPTILVPH PGGTSTPPMD RITYIPGTQI TFPPRPYNSA
1610 1620 1630 1640 1650
SMSPGHPTHL AAAASAERER EREREKERER ERIAAASSDL YLRPGSEQPG
1660 1670 1680 1690 1700
RPGSHGYVRS PSPSVRTQET MLQQRPSVFQ GTNGTSVITP LDPTAQLRIM
1710 1720 1730 1740 1750
PLPAGGPSIS QGLPASRYNT AADALAALVD AAASAPQMDV SKTKESKHEA
1760 1770 1780 1790 1800
ARLEENLRSR SAAVSEQQQL EQKTLEVEKR SVQCLYTSSA FPSGKPQPHS
1810 1820 1830 1840 1850
SVVYSEAGKD KGPPPKSRYE EELRTRGKTT ITAANFIDVI ITRQIASDKD
1860 1870 1880 1890 1900
ARERGSQSSD SSSSLSSHRY ETPSDAIEVI SPASSPAPPQ EKLQTYQPEV
1910 1920 1930 1940 1950
VKANQAENDP TRQYEGPLHH YRPQQESPSP QQQLPPSSQA EGMGQVPRTH
1960 1970 1980 1990 2000
RLITLADHIC QIITQDFARN QVSSQTPQQP PTSTFQNSPS ALVSTPVRTK
2010 2020 2030 2040 2050
TSNRYSPESQ AQSVHHQRPG SRVSPENLVD KSRGSRPGKS PERSHVSSEP
2060 2070 2080 2090 2100
YEPISPPQVP VVHEKQDSLL LLSQRGAEPA EQRNDARSPG SISYLPSFFT
2110 2120 2130 2140 2150
KLENTSPMVK SKKQEIFRKL NSSGGGDSDM AAAQPGTEIF NLPAVTTSGS
2160 2170 2180 2190 2200
VSSRGHSFAD PASNLGLEDI IRKALMGSFD DKVEDHGVVM SQPMGVVPGT
2210 2220 2230 2240 2250
ANTSVVTSGE TRREEGDPSP HSGVCKPKLI SKSNSRKSKS PIPGQGYLGT
2260 2270 2280 2290 2300
ERPSSVSSVH SEGDYHRQTP GWAWEDRPSS TGSTQFPYNP LTMRMLSSTP
2310 2320 2330 2340
PTPIACAPSA VNQAAPHQQN RIWEREPAPL LSAQYETLSD SDD
Length:2,343
Mass (Da):258,987
Last modified:October 29, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA354EF3A1E371EF5
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 12 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O75376NCOR1_HUMAN
Nuclear receptor corepressor 1
NCOR1 KIAA1047
2,440Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E7EVU5E7EVU5_HUMAN
Nuclear receptor corepressor 1
NCOR1
537Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E7EW50E7EW50_HUMAN
Nuclear receptor corepressor 1
NCOR1
545Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KS51J3KS51_HUMAN
Nuclear receptor corepressor 1
NCOR1
546Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JAP0C9JAP0_HUMAN
Nuclear receptor corepressor 1
NCOR1
125Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E7EVK1E7EVK1_HUMAN
Nuclear receptor corepressor 1
NCOR1
1,071Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KS29J3KS29_HUMAN
Nuclear receptor corepressor 1
NCOR1
184Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QKP0J3QKP0_HUMAN
Nuclear receptor corepressor 1
NCOR1
217Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KRE4J3KRE4_HUMAN
Nuclear receptor corepressor 1
NCOR1
183Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y459H0Y459_HUMAN
Nuclear receptor corepressor 1
NCOR1
92Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC002553 Genomic DNA No translation available.
AC005971 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000395857; ENSP00000379198; ENSG00000141027

UCSC genome browser

More...
UCSCi
uc002gpp.2 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002553 Genomic DNA No translation available.
AC005971 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

EPDiA0A088AWL3
jPOSTiA0A088AWL3
PeptideAtlasiA0A088AWL3
PRIDEiA0A088AWL3

Genome annotation databases

EnsembliENST00000395857; ENSP00000379198; ENSG00000141027
UCSCiuc002gpp.2 human

Organism-specific databases

HGNCiHGNC:7672 NCOR1
OpenTargetsiENSG00000141027

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1878 Eukaryota
ENOG410YDXP LUCA
GeneTreeiENSGT00940000155093

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
NCOR1 human

Gene expression databases

BgeeiENSG00000141027 Expressed in 227 organ(s), highest expression level in corpus callosum
ExpressionAtlasiA0A088AWL3 baseline and differential

Family and domain databases

CDDicd00167 SANT, 2 hits
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR031557 N-CoR_GPS2_interact
IPR001005 SANT/Myb
IPR017884 SANT_dom
PfamiView protein in Pfam
PF15784 GPS2_interact, 1 hit
PF00249 Myb_DNA-binding, 1 hit
SMARTiView protein in SMART
SM00717 SANT, 2 hits
SUPFAMiSSF46689 SSF46689, 2 hits
PROSITEiView protein in PROSITE
PS51293 SANT, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A088AWL3_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A088AWL3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: July 31, 2019
This is version 44 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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