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Entry version 30 (16 Oct 2019)
Sequence version 1 (29 Oct 2014)
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Protein
Submitted name:

Uncharacterized protein

Gene

brat

Organism
Apis mellifera (Honeybee)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:bratImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiApis mellifera (Honeybee)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7460 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaHymenopteraApocritaAculeataApoideaApidaeApis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005203 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A0A087ZVR7

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7460.GB42949-PA

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini66 – 114B box-typeInterPro annotationAdd BLAST49
Domaini146 – 179B box-typeInterPro annotationAdd BLAST34
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati528 – 571NHLPROSITE-ProRule annotationAdd BLAST44
Repeati575 – 620NHLPROSITE-ProRule annotationAdd BLAST46
Repeati621 – 662NHLPROSITE-ProRule annotationAdd BLAST42
Repeati663 – 705NHLPROSITE-ProRule annotationAdd BLAST43
Repeati706 – 749NHLPROSITE-ProRule annotationAdd BLAST44

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni359 – 391DisorderedSequence analysisAdd BLAST33

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi372 – 391PolarSequence analysisAdd BLAST20

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG2177 Eukaryota
ENOG410XQJ4 LUCA

KEGG Orthology (KO)

More...
KOi
K11997

Identification of Orthologs from Complete Genome Data

More...
OMAi
IYRYVQV

Database of Orthologous Groups

More...
OrthoDBi
489543at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A0A087ZVR7

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00021 BBOX, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.120.10.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011042 6-blade_b-propeller_TolB-like
IPR003649 Bbox_C
IPR001258 NHL_repeat
IPR013017 NHL_repeat_subgr
IPR000315 Znf_B-box

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01436 NHL, 4 hits
PF00643 zf-B_box, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00502 BBC, 1 hit
SM00336 BBOX, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51125 NHL, 5 hits
PS50119 ZF_BBOX, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A087ZVR7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASPTLSLES RANSIGSLAS LSPLTVSGSS PPASDSAICD VDSCDLCLDS
60 70 80 90 100
QKPGEAPCPR CRLGGAGGVR CTGCKSTESD AVARCFDCAN FLCPNCVMAH
110 120 130 140 150
QFMHCFEGHR VLNLGDSKLE TVTTSTANNE IPKNNLVINS GSSNGEKVPY
160 170 180 190 200
CPRHKQELLK YFCRTCTALV CKECAITDHP GPLHDCAHIS EVGTQQLEAM
210 220 230 240 250
ARVVQECRAK AADVRAAVKA ADHGAARLQV QYHKAQNEIN DTFQFYRSML
260 270 280 290 300
EERKQELLKE LESVFSTKQM SLGVLTQKAN DMADKMLQTC EFVERLTKYT
310 320 330 340 350
TVTEVLMVKK LLDSKLQLLL NYTPDIASQT ADLEFVSNYQ AIQVGVRNTF
360 370 380 390 400
GYVRSNNESN AGPIGKQPPI ARPTALSNNG NGGSNANNGP NSAGSLGGLL
410 420 430 440 450
LDRSYSNGLI SSTSTCASST SPSSFDTNNT VITKRFSSAN SLGPFSTTIS
460 470 480 490 500
DLNLNGINAN PYEKWSNGGS DVYPVVTTND HFPMPTSVAV AANAASSDSV
510 520 530 540 550
LDLTSKLMSA TVIFPPKSQI KRQKMIYHCK FGEFGVMEGQ FTEPSGVAVN
560 570 580 590 600
AQNDIIVADT NNHRIQIFDK EGRFKFQFGE CGKRDGQLLY PNRVAVVKTS
610 620 630 640 650
GDIIVTERSP THQIQIYNQY GQFVRKFGAN ILQHPRGVTV DSKGRIVVVE
660 670 680 690 700
CKVMRVIIFD QAGIVLQKFG CSKHLEFPNG VVVNDKQEIF ISDNRAHCVK
710 720 730 740 750
VFNYEGAYLR QIGGEGITNY PIGVGINAVG EILIADNHNN FNLTIFTQDG
760 770 780 790
QLVSALESKV KHAQCFDVAL MDDGSVVLAS KDYRLYIYRY VQVPPIGM
Length:798
Mass (Da):86,854
Last modified:October 29, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB25AA91C619AE7D9
GO

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_003251836.1, XM_003251788.3
XP_006571982.1, XM_006571919.2
XP_006571984.1, XM_006571921.2
XP_006571986.1, XM_006571923.2
XP_016772787.1, XM_016917298.1
XP_016772788.1, XM_016917299.1
XP_016772789.1, XM_016917300.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
GB42949-RA; GB42949-PA; GB42949

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
412853

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ame:412853

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_003251836.1, XM_003251788.3
XP_006571982.1, XM_006571919.2
XP_006571984.1, XM_006571921.2
XP_006571986.1, XM_006571923.2
XP_016772787.1, XM_016917298.1
XP_016772788.1, XM_016917299.1
XP_016772789.1, XM_016917300.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi7460.GB42949-PA

Proteomic databases

PaxDbiA0A087ZVR7

Genome annotation databases

EnsemblMetazoaiGB42949-RA; GB42949-PA; GB42949
GeneIDi412853
KEGGiame:412853

Phylogenomic databases

eggNOGiKOG2177 Eukaryota
ENOG410XQJ4 LUCA
KOiK11997
OMAiIYRYVQV
OrthoDBi489543at2759
PhylomeDBiA0A087ZVR7

Family and domain databases

CDDicd00021 BBOX, 1 hit
Gene3Di2.120.10.30, 1 hit
InterProiView protein in InterPro
IPR011042 6-blade_b-propeller_TolB-like
IPR003649 Bbox_C
IPR001258 NHL_repeat
IPR013017 NHL_repeat_subgr
IPR000315 Znf_B-box
PfamiView protein in Pfam
PF01436 NHL, 4 hits
PF00643 zf-B_box, 1 hit
SMARTiView protein in SMART
SM00502 BBC, 1 hit
SM00336 BBOX, 2 hits
PROSITEiView protein in PROSITE
PS51125 NHL, 5 hits
PS50119 ZF_BBOX, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A087ZVR7_APIME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A087ZVR7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: October 16, 2019
This is version 30 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health

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