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Protein
Submitted name:

Laminin, beta 2-like

Gene
N/A
Organism
Poecilia formosa (Amazon molly) (Limia formosa)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Laminin, beta 2-likeImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPoecilia formosa (Amazon molly) (Limia formosa)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri48698 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeCyprinodontiformesPoeciliidaePoeciliinaePoecilia
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000028760 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 27Sequence analysisAdd BLAST27
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500183477228 – 1846Sequence analysisAdd BLAST1819

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi307 ↔ 316PROSITE-ProRule annotation
Disulfide bondi372 ↔ 381PROSITE-ProRule annotation
Disulfide bondi435 ↔ 444PROSITE-ProRule annotation
Disulfide bondi488 ↔ 497PROSITE-ProRule annotation
Disulfide bondi500 ↔ 514PROSITE-ProRule annotation
Disulfide bondi517 ↔ 529PROSITE-ProRule annotation
Disulfide bondi519 ↔ 536PROSITE-ProRule annotation
Disulfide bondi538 ↔ 547PROSITE-ProRule annotation
Disulfide bondi828 ↔ 840PROSITE-ProRule annotation
Disulfide bondi830 ↔ 847PROSITE-ProRule annotation
Disulfide bondi849 ↔ 858PROSITE-ProRule annotation
Disulfide bondi876 ↔ 888PROSITE-ProRule annotation
Disulfide bondi878 ↔ 895PROSITE-ProRule annotation
Disulfide bondi897 ↔ 906PROSITE-ProRule annotation
Disulfide bondi941 ↔ 950PROSITE-ProRule annotation
Disulfide bondi1001 ↔ 1010PROSITE-ProRule annotation
Disulfide bondi1055 ↔ 1064PROSITE-ProRule annotation
Disulfide bondi1111 ↔ 1120PROSITE-ProRule annotation
Disulfide bondi1139 ↔ 1151PROSITE-ProRule annotation
Disulfide bondi1141 ↔ 1158PROSITE-ProRule annotation
Disulfide bondi1160 ↔ 1169PROSITE-ProRule annotation
Disulfide bondi1187 ↔ 1199PROSITE-ProRule annotation
Disulfide bondi1189 ↔ 1206PROSITE-ProRule annotation
Disulfide bondi1208 ↔ 1217PROSITE-ProRule annotation

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini38 – 277Laminin N-terminalInterPro annotationAdd BLAST240
Domaini278 – 341Laminin EGF-likeInterPro annotationAdd BLAST64
Domaini342 – 404Laminin EGF-likeInterPro annotationAdd BLAST63
Domaini405 – 464Laminin EGF-likeInterPro annotationAdd BLAST60
Domaini465 – 516Laminin EGF-likeInterPro annotationAdd BLAST52
Domaini517 – 558Laminin EGF-likeInterPro annotationAdd BLAST42
Domaini556 – 822Laminin IV type BInterPro annotationAdd BLAST267
Domaini828 – 875Laminin EGF-likeInterPro annotationAdd BLAST48
Domaini876 – 921Laminin EGF-likeInterPro annotationAdd BLAST46
Domaini922 – 971Laminin EGF-likeInterPro annotationAdd BLAST50
Domaini972 – 1030Laminin EGF-likeInterPro annotationAdd BLAST59
Domaini973 – 1011EGF-likeInterPro annotationAdd BLAST39
Domaini1031 – 1082Laminin EGF-likeInterPro annotationAdd BLAST52
Domaini1083 – 1138Laminin EGF-likeInterPro annotationAdd BLAST56
Domaini1139 – 1186Laminin EGF-likeInterPro annotationAdd BLAST48
Domaini1187 – 1233Laminin EGF-likeInterPro annotationAdd BLAST47

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1276 – 1296Sequence analysisAdd BLAST21
Coiled coili1341 – 1361Sequence analysisAdd BLAST21
Coiled coili1434 – 1454Sequence analysisAdd BLAST21
Coiled coili1510 – 1530Sequence analysisAdd BLAST21
Coiled coili1623 – 1650Sequence analysisAdd BLAST28
Coiled coili1658 – 1685Sequence analysisAdd BLAST28
Coiled coili1742 – 1762Sequence analysisAdd BLAST21
Coiled coili1772 – 1792Sequence analysisAdd BLAST21
Coiled coili1800 – 1841Sequence analysisAdd BLAST42

Keywords - Domaini

Coiled coilSequence analysis, EGF-like domainPROSITE-ProRule annotation, Laminin EGF-like domainPROSITE-ProRule annotationSAAS annotation, RepeatSAAS annotation, SignalSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000167093

Identification of Orthologs from Complete Genome Data

More...
OMAi
PRPFCFE

Database of Orthologous Groups

More...
OrthoDBi
65841at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.1490, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR002049 Laminin_EGF
IPR013015 Laminin_IV_B
IPR008211 Laminin_N
IPR038684 Laminin_N_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00053 Laminin_EGF, 12 hits
PF00055 Laminin_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00181 EGF, 9 hits
SM00180 EGF_Lam, 13 hits
SM00136 LamNT, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00022 EGF_1, 1 hit
PS50026 EGF_3, 1 hit
PS01248 EGF_LAM_1, 6 hits
PS50027 EGF_LAM_2, 13 hits
PS51116 LAMININ_IVB, 1 hit
PS51117 LAMININ_NTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A087YNH3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSIHLAIKMP IKIIHLSLLV LALNAFGQEL PSSPHGCTEG SCYPATGNLL
60 70 80 90 100
IGRAVNLTAT STCGLDGPEQ FCIVSYLQDP EKCFECDSRR PYDPYHHRNS
110 120 130 140 150
HRIENVIYLT DLNGNENFWK SVNGKEDVSI RLNLEAEFHF THLIMKFKTF
160 170 180 190 200
RPAALIIERS ADFGRTWRPY RYFAKNCTRT FPGIPANGLH HINDVICEER
210 220 230 240 250
YSDIEPSKDG EVIFKVLDPA IPVEDPYSLE IQELLRITNL RINFTKLNTL
260 270 280 290 300
GDDLLDRRSD VLQKYYYAIN ELVVRGSCFC YGHASECAPV PGVNTHETGM
310 320 330 340 350
IHGRCVCKHN TEGLNCERCK VFHNDSPWRP AETEDPHTCR ECNCNGHTNQ
360 370 380 390 400
CHFDMAVYLA LGNTSGGVCD NCLHNTMGRN CEMCKPFYYQ DPNRDIRDPR
410 420 430 440 450
VCVACDCDPV GSLEGGMCDS HTDLGMGMIA GQCRCKYNVK GKRCDDCKAG
460 470 480 490 500
YYGLSESDPL GCQPCNCDPR GIILMDAPCD QISGDCSCKR YVTGRYCNQC
510 520 530 540 550
LPEYWGLSND LGGCRPCECD FGGAYNNRCM MDSGQCDCRR HFIGRQCSEV
560 570 580 590 600
QPGYFCAPLD YYKYEAEEAA GRSPTDPSLP GQVRPQAADD CIQQLSNQAR
610 620 630 640 650
RHRRHRRISS LQQSQAALRR IRQLQQTPDV TTVHREHAPS HITTWTGPGF
660 670 680 690 700
ARVKDGAGLV FTIDNIPYAM EYEVMIRYEP ESTEDWEAVV SITSVELPSS
710 720 730 740 750
LRCGNLLPAE QLYTETLLHR NRYILMSRPF CFEPSNRYVI AIRFQRHGVA
760 770 780 790 800
YRHLTAFILI DSLVLIPKYT ELPGFHGSDP DSEQHREDMI RYMCLDSFMI
810 820 830 840 850
TPMPALAEMC SKLICGISAN IHDGALACQC DPQGSISGEC DKVGGQCRCK
860 870 880 890 900
ANVIGRQCDQ CAPGTYGFGV NGCNACDCHP EGSFSHQCDP VTGQCPCRQG
910 920 930 940 950
ATGRQCSDCQ PGQWGFPSCS PCQCNGHADL CDPRTGECRG CRDNTAGHLC
960 970 980 990 1000
ERCVEGFYGN PVLGSGDHCH PCPCPGNPGS NHFNGHSCQT DHTSDQIICN
1010 1020 1030 1040 1050
CKPGYTGPRC DQCAPGYYGN PEQPGGQCLR CECNDNIDPQ DPGSCDPRTG
1060 1070 1080 1090 1100
QCLRCLYHTD GPSCSRCEEG YFGNALIRDC RRCTCVTAGT VVSACSEGQC
1110 1120 1130 1140 1150
LCDHYTGACP CRASVMGNNC DQCAPNHWNY GQPEGCQPCN CDQRHSEGDW
1160 1170 1180 1190 1200
CNMFTGQCPC WPGFGGQRCT ECREHHWGDP QVECRECGCH PLGSQTRQCN
1210 1220 1230 1240 1250
RVTGQCECKD GMAGVRCDEC ARGFTGVFPN CVPCHQCFYQ ADDHLCQIRR
1260 1270 1280 1290 1300
DLEHIQYAVQ KILESGITPG DGMNRITELE QKLNQVRDLI DTGDTERIHQ
1310 1320 1330 1340 1350
LIGQSIDDLR PEIVLINSRL TGIDQDTNKT KEADEVLRRT LTDLEKELMD
1360 1370 1380 1390 1400
VNATLALKQE LLDKYLTSGF LDQFDKVKKY YQVSQQAEER CNASVLFPTS
1410 1420 1430 1440 1450
PVEQSKQTRG ITEKLLNTTK GQLLRNLTAH NNSLNELHQK TQNLSETVQH
1460 1470 1480 1490 1500
LSQKVCGGAS NTSQHGSCSD NQCGCHDNQG NFVCGGEGCN GTKSSSLTAL
1510 1520 1530 1540 1550
KDATNLTDSL KAAMKELQGV TKKLQDIASQ TQDVKNRTMN ALEKAQKKKE
1560 1570 1580 1590 1600
YFEKSNKDLK DFIKTIKDFL TEEGADPESI QKVAQQVLDI NLPLNRTTVD
1610 1620 1630 1640 1650
KLINQINSSI ANLTNVQDIM NQTSQFIRNA QDLMNKAKEA ERQAVGVRDL
1660 1670 1680 1690 1700
VNSTKQALNV SEVAIEKAKA ALKEARHNLN STKNSTAEVE KGLVQLEDKQ
1710 1720 1730 1740 1750
MDIMMLLTNL SKGVEALKNK TEMNRLMAKD AINLANNATH QASTLVQKLN
1760 1770 1780 1790 1800
VTEKRYRELQ LKMESLGSSG TLNNIQQKVK DMTKDAEDLL SKANNGINDL
1810 1820 1830 1840
DKLGELLKSN EERMKKQREE LEDLKQNATD VRDQIQEEVR KYSSCV
Length:1,846
Mass (Da):205,829
Last modified:November 26, 2014 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7921BD1057210BA9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AYCK01014099 Genomic DNA No translation available.
AYCK01014100 Genomic DNA No translation available.
AYCK01014101 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_007571360.1, XM_007571298.2
XP_007571361.1, XM_007571299.2
XP_016536854.1, XM_016681368.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSPFOT00000019598; ENSPFOP00000019576; ENSPFOG00000019449

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
103151312

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AYCK01014099 Genomic DNA No translation available.
AYCK01014100 Genomic DNA No translation available.
AYCK01014101 Genomic DNA No translation available.
RefSeqiXP_007571360.1, XM_007571298.2
XP_007571361.1, XM_007571299.2
XP_016536854.1, XM_016681368.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPFOT00000019598; ENSPFOP00000019576; ENSPFOG00000019449
GeneIDi103151312

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
3913

Phylogenomic databases

GeneTreeiENSGT00940000167093
OMAiPRPFCFE
OrthoDBi65841at2759

Family and domain databases

Gene3Di2.60.120.1490, 1 hit
InterProiView protein in InterPro
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR002049 Laminin_EGF
IPR013015 Laminin_IV_B
IPR008211 Laminin_N
IPR038684 Laminin_N_sf
PfamiView protein in Pfam
PF00053 Laminin_EGF, 12 hits
PF00055 Laminin_N, 1 hit
SMARTiView protein in SMART
SM00181 EGF, 9 hits
SM00180 EGF_Lam, 13 hits
SM00136 LamNT, 1 hit
PROSITEiView protein in PROSITE
PS00022 EGF_1, 1 hit
PS50026 EGF_3, 1 hit
PS01248 EGF_LAM_1, 6 hits
PS50027 EGF_LAM_2, 13 hits
PS51116 LAMININ_IVB, 1 hit
PS51117 LAMININ_NTER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A087YNH3_POEFO
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A087YNH3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: November 26, 2014
Last modified: January 16, 2019
This is version 36 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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