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Entry version 31 (16 Oct 2019)
Sequence version 2 (26 Nov 2014)
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Protein

UDENN domain-containing protein

Gene
N/A
Organism
Poecilia formosa (Amazon molly) (Limia formosa)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
UDENN domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPoecilia formosa (Amazon molly) (Limia formosa)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri48698 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeCyprinodontiformesPoeciliidaePoeciliinaePoecilia
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000028760 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
48698.ENSPFOP00000004371

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini13 – 576UDENNInterPro annotationAdd BLAST564

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni103 – 182DisorderedSequence analysisAdd BLAST80
Regioni619 – 648DisorderedSequence analysisAdd BLAST30
Regioni691 – 728DisorderedSequence analysisAdd BLAST38
Regioni781 – 855DisorderedSequence analysisAdd BLAST75
Regioni889 – 934DisorderedSequence analysisAdd BLAST46
Regioni1046 – 1077DisorderedSequence analysisAdd BLAST32
Regioni1123 – 1267DisorderedSequence analysisAdd BLAST145

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili977 – 997Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi116 – 131PolarSequence analysisAdd BLAST16
Compositional biasi144 – 167PolarSequence analysisAdd BLAST24
Compositional biasi705 – 728PolarSequence analysisAdd BLAST24
Compositional biasi806 – 823PolarSequence analysisAdd BLAST18
Compositional biasi838 – 855PolarSequence analysisAdd BLAST18
Compositional biasi913 – 934PolarSequence analysisAdd BLAST22
Compositional biasi1123 – 1154PolyampholyteSequence analysisAdd BLAST32
Compositional biasi1155 – 1211PolarSequence analysisAdd BLAST57
Compositional biasi1228 – 1252PolarSequence analysisAdd BLAST25

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156718

Identification of Orthologs from Complete Genome Data

More...
OMAi
ETFSMSK

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001194 cDENN_dom
IPR005112 dDENN_dom
IPR039980 MADD
IPR037516 Tripartite_DENN
IPR005113 uDENN_dom

The PANTHER Classification System

More...
PANTHERi
PTHR13008 PTHR13008, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02141 DENN, 1 hit
PF03456 uDENN, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00801 dDENN, 1 hit
SM00799 DENN, 1 hit
SM00800 uDENN, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50211 DENN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A087XF18-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEKKKICPRL LDYLVVVGAR QPSSDSVAQT PQLLRRYPLE DHHDFPLPPD
60 70 80 90 100
VVFFCQPEGC LSIRQRRVSL RDDSSFVFTL TDKDSGITRY GICVNFYRSF
110 120 130 140 150
QRGHHRPRDK SSHTETAAQA VESTNEMSDG SSGGHVAAPS APDNSKSEAP
160 170 180 190 200
SSSGEESGQP GPEQTSGKSP QHKRRAAKMA ARNRNSTLTS LCILSHYPFF
210 220 230 240 250
TTFRECLYIL KRLVDCCSQR LTQRAGLSRA TQRDTMWRVF TGALSVEEKG
260 270 280 290 300
SQLLVDLRDI ESWVYRLLRS PVPLAGQRRV DVEVLPQELK RPLTFALPDN
310 320 330 340 350
SRFSLVDFPL HLPLELLGVD ACLQVLSCVL LEHKVILQSR DYNALSMSVM
360 370 380 390 400
AFVAMIYPLE YMFPVIPLLP TCMASAEQLL LAPTPYIIGV PASFFLYKSD
410 420 430 440 450
FKMPDDVWLV DLDSSKVIAP TNAENLPPLP EPEAGELKKH LKQALASMSL
460 470 480 490 500
NTQPILNLEK FQEGQEMTLL PPGRDKASPS STEFNPLIYG NDVDSVDVAT
510 520 530 540 550
RVAMVRFFNS PNVLQGFQMH TRTLRLFPRP VVAFQSTSFL ASRPRRSCFA
560 570 580 590 600
DKLSHTQAVE FYGEWALNPT NLAFQRIHNN VYDPSLIGDK SKWYAHQLQP
610 620 630 640 650
VVYRVYDGSS LLVEAMAGPL EDEGNESDPT DSGSDSDGYD DSSSSYSSLG
660 670 680 690 700
DLVSEMIQGD IQGDTPSLDP PTHAALGDAS EVEFQDLHDL KDSHSVDGPS
710 720 730 740 750
SGEGAAEQSD GQPLRSSSST TASSSPSTII QGVNHEQAEA PEIEASASAA
760 770 780 790 800
LQNPVPGIGS QPFLRPAADS GLVDSVNKKQ EYDNPYFEPQ YGFPTEEDAE
810 820 830 840 850
EEQVESYTPR FNQNLNGNKA QRPLRPSSLR LPGESDGEGD SRNSSPNSTI
860 870 880 890 900
SNSSNDGFGG LMSFASNLYK NHGTSFSLSN LALPNKAARE KSTPFPSLKG
910 920 930 940 950
ARAPRALVDQ KSSVIKHSPT VKRESPSPQG RVNNTSENQQ FLKEVVQSVL
960 970 980 990 1000
EGQGVGWLNM KKVRRLLENE QLRVFVLSKL NRAVQSEEDA RQEIIRDVEV
1010 1020 1030 1040 1050
NRKVYKGMLD ILKCTVSSLE HSYTNAGLGG MASVFSLLEI ARTHYQTKDP
1060 1070 1080 1090 1100
EKRKRSPTDS AGSPGSKESP SGRMETARPQ GLLNIPQLQL PHHTTGKGAR
1110 1120 1130 1140 1150
HFDTRSLNEE NFIASIELWS KHQDKQKAME KQQRAEGVKQ QRPQVTDAEE
1160 1170 1180 1190 1200
KKSQISADSG LSVASGSQKS DTESVTSSEP PILTRSTSQD SEASTVISNS
1210 1220 1230 1240 1250
SGETLGADSD LSSTAGDGLG GRAAPHLNQS RGTLSDSEIE TNPATSSVFG
1260 1270 1280 1290 1300
KTHTLKPGAK DHLPAMVKGP PVQPMEDISM RIYLFEGLLG RDKSSVWDQL
1310 1320 1330 1340 1350
EDAAMETFSL SKERSTLWDQ VQFWEDAFLD AVMLEREGMG MDQGPQEMIE
1360 1370 1380 1390 1400
RYLSLGEHDR KRLEDDEDRL LATLLHNMIA YMLMIKVNKN DIRKKVRRLM
1410 1420 1430 1440 1450
GKSHIGLTYS QEINEILDKL AHMNGRELSI RPSGSRHIKK QTFVVHAGTD
1460 1470 1480 1490 1500
TTGDIFFMEV CDDCIVLRSN VGTVYERWWY EKLINMTYCP KTKVLCLWRR
1510 1520 1530 1540 1550
NGQETQLNKF YTKKCRELYY CVKDSMERAA ARQQSIKPGP ELGGEFPVQD
1560 1570 1580 1590 1600
MKTGEGGLLQ VTLEGINLKF MHSQERKVFI ELSHIKKCNT VKGVFVLEEF
1610 1620 1630 1640 1650
VPETKEVVIH KYKTPMAHQI CYSVLCLFSY VAAVKGKEAE GKPKLLSPRP

LPS
Length:1,653
Mass (Da):183,558
Last modified:November 26, 2014 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFA4153B17B7B0490
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A096MB12A0A096MB12_POEFO
UDENN domain-containing protein
1,622Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AYCK01012808 Genomic DNA No translation available.
AYCK01012809 Genomic DNA No translation available.
AYCK01012810 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_016535633.1, XM_016680147.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSPFOT00000004379; ENSPFOP00000004371; ENSPFOG00000003955

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
103149705

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AYCK01012808 Genomic DNA No translation available.
AYCK01012809 Genomic DNA No translation available.
AYCK01012810 Genomic DNA No translation available.
RefSeqiXP_016535633.1, XM_016680147.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi48698.ENSPFOP00000004371

Genome annotation databases

EnsembliENSPFOT00000004379; ENSPFOP00000004371; ENSPFOG00000003955
GeneIDi103149705

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
8567

Phylogenomic databases

GeneTreeiENSGT00940000156718
OMAiETFSMSK

Family and domain databases

InterProiView protein in InterPro
IPR001194 cDENN_dom
IPR005112 dDENN_dom
IPR039980 MADD
IPR037516 Tripartite_DENN
IPR005113 uDENN_dom
PANTHERiPTHR13008 PTHR13008, 1 hit
PfamiView protein in Pfam
PF02141 DENN, 1 hit
PF03456 uDENN, 1 hit
SMARTiView protein in SMART
SM00801 dDENN, 1 hit
SM00799 DENN, 1 hit
SM00800 uDENN, 1 hit
PROSITEiView protein in PROSITE
PS50211 DENN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A087XF18_POEFO
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A087XF18
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: November 26, 2014
Last modified: October 16, 2019
This is version 31 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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