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Entry version 44 (31 Jul 2019)
Sequence version 1 (29 Oct 2014)
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Protein
Submitted name:

Atrial natriuretic peptide-converting enzyme

Gene

CORIN

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei739Charge relay systemUniRule annotation1
Active sitei788Charge relay systemUniRule annotation1
Active sitei881Charge relay systemUniRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Atrial natriuretic peptide-converting enzymeImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CORINImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:19012 CORIN

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei46 – 71HelicalSequence analysisAdd BLAST26

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000145244

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi149 ↔ 173PROSITE-ProRule annotation
Disulfide bondi210 ↔ 228PROSITE-ProRule annotation
Disulfide bondi222 ↔ 237PROSITE-ProRule annotation
Disulfide bondi239 ↔ 251PROSITE-ProRule annotation
Disulfide bondi246 ↔ 264PROSITE-ProRule annotation
Disulfide bondi258 ↔ 273PROSITE-ProRule annotation
Disulfide bondi283 ↔ 301PROSITE-ProRule annotation
Disulfide bondi295 ↔ 310PROSITE-ProRule annotation
Disulfide bondi398 ↔ 436PROSITE-ProRule annotation
Disulfide bondi425 ↔ 466PROSITE-ProRule annotation
Disulfide bondi429 ↔ 453PROSITE-ProRule annotation
Disulfide bondi476 ↔ 488PROSITE-ProRule annotation
Disulfide bondi483 ↔ 501PROSITE-ProRule annotation
Disulfide bondi495 ↔ 510PROSITE-ProRule annotation
Disulfide bondi533 ↔ 548PROSITE-ProRule annotation
Disulfide bondi551 ↔ 563PROSITE-ProRule annotation
Disulfide bondi558 ↔ 576PROSITE-ProRule annotation
Disulfide bondi570 ↔ 585PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
A0A087X1D5

PeptideAtlas

More...
PeptideAtlasi
A0A087X1D5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000145244 Expressed in 118 organ(s), highest expression level in heart

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A0A087X1D5 baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini67 – 192FZInterPro annotationAdd BLAST126
Domaini346 – 469FZInterPro annotationAdd BLAST124
Domaini698 – 931Peptidase S1InterPro annotationAdd BLAST234

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 24DisorderedSequence analysisAdd BLAST24

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi7 – 21PolyampholyteSequence analysisAdd BLAST15

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3577 Eukaryota
KOG3627 Eukaryota
COG5640 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157103

Database of Orthologous Groups

More...
OrthoDBi
1314811at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07445 CRD_corin_1, 1 hit
cd07888 CRD_corin_2, 1 hit
cd00112 LDLa, 6 hits
cd00190 Tryp_SPc, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.2000.10, 2 hits
4.10.400.10, 6 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR017052 Corin
IPR041762 Corin_CRD_1
IPR041763 Corin_CRD_2
IPR020067 Frizzled_dom
IPR036790 Frizzled_dom_sf
IPR036055 LDL_receptor-like_sf
IPR023415 LDLR_class-A_CS
IPR002172 LDrepeatLR_classA_rpt
IPR009003 Peptidase_S1_PA
IPR017448 SRCR-like_dom
IPR036772 SRCR-like_dom_sf
IPR001254 Trypsin_dom
IPR033116 TRYPSIN_SER

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01392 Fz, 2 hits
PF00057 Ldl_recept_a, 5 hits
PF15494 SRCR_2, 1 hit
PF00089 Trypsin, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF036376 Corin, 3 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00261 LDLRECEPTOR

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00063 FRI, 2 hits
SM00192 LDLa, 6 hits
SM00202 SR, 1 hit
SM00020 Tryp_SPc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50494 SSF50494, 1 hit
SSF56487 SSF56487, 1 hit
SSF57424 SSF57424, 6 hits
SSF63501 SSF63501, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50038 FZ, 2 hits
PS01209 LDLRA_1, 2 hits
PS50068 LDLRA_2, 6 hits
PS50240 TRYPSIN_DOM, 1 hit
PS00135 TRYPSIN_SER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

A0A087X1D5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKQSPALAPE ERCRRAGSPK PVLRADDNNM GNGCSQKLAT ANLLRFLLLV
60 70 80 90 100
LIPCICALVL LLVILLSYVG ACMNITHSQC QMLPYHATLT PLLSVVRNME
110 120 130 140 150
MEKFLKFFTY LHRLSCYQHI MLFGCTLAFP ECIIDGDDSH GLLPCRSFCE
160 170 180 190 200
AAKEGCESVL GMVNYSWPDF LRCSQFRNQT ESSNVSRICF SPQQENGKQL
210 220 230 240 250
LCGRGENFLC ASGICIPGKL QCNGYNDCDD WSDEAHCNCS ENLFHCHTGK
260 270 280 290 300
CLNYSLVCDG YDDCGDLSDE QNCACHSQGL VECRNGQCIP STFQCDGDED
310 320 330 340 350
CKDGSDEENC SVIQTSCQEG DQRCLYNPCL DSCGGSSLCD PNNSLNNCSQ
360 370 380 390 400
CEPITLELCM NLPYNSTSYP NYFGHRTQKE ASISWESSLF PALVQTNCYK
410 420 430 440 450
YLMFFSCTIL VPKCDVNTGE HIPPCRALCE HSKERCESVL GIVGLQWPED
460 470 480 490 500
TDCSQFPEEN SDNQTCLMPD EYVEECSPSH FKCRSGQCVL ASRRCDGQAD
510 520 530 540 550
CDDDSDEENC GCKERDLWEC PSNKQCLKHT VICDGFPDCP DYMDEKNCSF
560 570 580 590 600
CQDDELECAN HACVSRDLWC DGEADCSDSS DEWDCVTLSI NVNSSSFLMV
610 620 630 640 650
HRAATEHHVC ADGWQEILSQ LACKQMGLGE PSVTKLIQEQ EKEPRWLTLH
660 670 680 690 700
SNWESLNGTT LHELLVNGQS CESRSKISLL CTKQDCGRRP AARMNKRILG
710 720 730 740 750
GRTSRPGRWP WQCSLQSEPS GHICGCVLIA KKWVLTVAHC FEGRENAAVW
760 770 780 790 800
KVVLGINNLD HPSVFMQTRF VKTIILHPRY SRAVVDYDIS IVELSEDISE
810 820 830 840 850
TGYVRPVCLP NPEQWLEPDT YCYITGWGHM GNKMPFKLQE GEVRIISLEH
860 870 880 890 900
CQSYFDMKTI TTRMICAGYE SGTVDSCMGD SGGPLVCEKP GGRWTLFGLT
910 920 930
SWGSVCFSKV LGPGVYSNVS YFVEWIKRQI YIQTFLLN
Length:938
Mass (Da):105,121
Last modified:October 29, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i943C7FC5E7D21C10
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9Y5Q5CORIN_HUMAN
Atrial natriuretic peptide-converti...
CORIN CRN, TMPRSS10
1,042Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KR88J3KR88_HUMAN
Atrial natriuretic peptide-converti...
CORIN
975Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KR90J3KR90_HUMAN
Atrial natriuretic peptide-converti...
CORIN
1,005Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E7EQE7E7EQE7_HUMAN
Atrial natriuretic peptide-converti...
CORIN
903Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KR83J3KR83_HUMAN
Atrial natriuretic peptide-converti...
CORIN
734Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC092597 Genomic DNA No translation available.
AC104646 Genomic DNA No translation available.
AC107068 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
NP_001265514.1, NM_001278585.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000610355; ENSP00000484087; ENSG00000145244

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
10699

UCSC genome browser

More...
UCSCi
uc032tif.2 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC092597 Genomic DNA No translation available.
AC104646 Genomic DNA No translation available.
AC107068 Genomic DNA No translation available.
RefSeqiNP_001265514.1, NM_001278585.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

jPOSTiA0A087X1D5
PeptideAtlasiA0A087X1D5

Genome annotation databases

EnsembliENST00000610355; ENSP00000484087; ENSG00000145244
GeneIDi10699
UCSCiuc032tif.2 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10699
HGNCiHGNC:19012 CORIN
OpenTargetsiENSG00000145244

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3577 Eukaryota
KOG3627 Eukaryota
COG5640 LUCA
GeneTreeiENSGT00940000157103
OrthoDBi1314811at2759

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CORIN human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
10699

Gene expression databases

BgeeiENSG00000145244 Expressed in 118 organ(s), highest expression level in heart
ExpressionAtlasiA0A087X1D5 baseline and differential

Family and domain databases

CDDicd07445 CRD_corin_1, 1 hit
cd07888 CRD_corin_2, 1 hit
cd00112 LDLa, 6 hits
cd00190 Tryp_SPc, 1 hit
Gene3Di1.10.2000.10, 2 hits
4.10.400.10, 6 hits
InterProiView protein in InterPro
IPR017052 Corin
IPR041762 Corin_CRD_1
IPR041763 Corin_CRD_2
IPR020067 Frizzled_dom
IPR036790 Frizzled_dom_sf
IPR036055 LDL_receptor-like_sf
IPR023415 LDLR_class-A_CS
IPR002172 LDrepeatLR_classA_rpt
IPR009003 Peptidase_S1_PA
IPR017448 SRCR-like_dom
IPR036772 SRCR-like_dom_sf
IPR001254 Trypsin_dom
IPR033116 TRYPSIN_SER
PfamiView protein in Pfam
PF01392 Fz, 2 hits
PF00057 Ldl_recept_a, 5 hits
PF15494 SRCR_2, 1 hit
PF00089 Trypsin, 1 hit
PIRSFiPIRSF036376 Corin, 3 hits
PRINTSiPR00261 LDLRECEPTOR
SMARTiView protein in SMART
SM00063 FRI, 2 hits
SM00192 LDLa, 6 hits
SM00202 SR, 1 hit
SM00020 Tryp_SPc, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit
SSF56487 SSF56487, 1 hit
SSF57424 SSF57424, 6 hits
SSF63501 SSF63501, 2 hits
PROSITEiView protein in PROSITE
PS50038 FZ, 2 hits
PS01209 LDLRA_1, 2 hits
PS50068 LDLRA_2, 6 hits
PS50240 TRYPSIN_DOM, 1 hit
PS00135 TRYPSIN_SER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A087X1D5_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A087X1D5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: July 31, 2019
This is version 44 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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