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Protein
Submitted name:

Zinc finger protein 445

Gene

ZNF445

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Zinc finger protein 445Imported
Gene namesi
Name:ZNF445Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000185219.16
HGNCiHGNC:21018 ZNF445

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000185219

Expressioni

Gene expression databases

BgeeiENSG00000185219 Expressed in 210 organ(s), highest expression level in amniotic fluid
ExpressionAtlasiA0A087X0J9 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini54 – 136SCAN boxInterPro annotationAdd BLAST83
Domaini232 – 273KRABInterPro annotationAdd BLAST42

Phylogenomic databases

GeneTreeiENSGT00900000141186

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
cd07936 SCAN, 1 hit
Gene3Di1.10.4020.10, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR003309 SCAN_dom
IPR038269 SCAN_sf
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF02023 SCAN, 1 hit
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00431 SCAN, 1 hit
SUPFAMiSSF109640 SSF109640, 1 hit
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS50804 SCAN_BOX, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A087X0J9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPPGRWHAAI SSGPVFEGAR ALQTVKKEEE DESYTPVQAA RPQTLNRPGQ
60 70 80 90 100
ELFRQLFRQL RYHESSGPLE TLSRLRELCR WWLRPDVLSK AQILELLVLE
110 120 130 140 150
QFLSILPGEL RVWVQLHNPE SGEELWPCWR SCRGTLMGHP GGTRALPEPR
160 170 180 190 200
CALDGYRSLR SAQIWSLASP LRSSSALGDH LEPPYEIEAR DFLAGQSDTP
210 220 230 240 250
AAQMPALFPR EGCPGDQVTP TRSLTAQLQE TMTFKDVEVT FSQDEWGWLD
260 270
SAQRNLYRDV MLENYRNMAS LGK
Length:273
Mass (Da):31,043
Last modified:October 29, 2014 - v1
Checksum:i5DF314C254E696E1
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P59923ZN445_HUMAN
Zinc finger protein 445
ZNF445 ZKSCAN15, ZNF168
1,031Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC099669 Genomic DNA No translation available.
AC134943 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000617032; ENSP00000483454; ENSG00000185219
ENST00000635138; ENSP00000488919; ENSG00000283034
UCSCiuc062iuu.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC099669 Genomic DNA No translation available.
AC134943 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000617032; ENSP00000483454; ENSG00000185219
ENST00000635138; ENSP00000488919; ENSG00000283034
UCSCiuc062iuu.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000185219.16
HGNCiHGNC:21018 ZNF445
OpenTargetsiENSG00000185219
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00900000141186

Miscellaneous databases

ChiTaRSiZNF445 human

Gene expression databases

BgeeiENSG00000185219 Expressed in 210 organ(s), highest expression level in amniotic fluid
ExpressionAtlasiA0A087X0J9 baseline and differential

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
cd07936 SCAN, 1 hit
Gene3Di1.10.4020.10, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR003309 SCAN_dom
IPR038269 SCAN_sf
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF02023 SCAN, 1 hit
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00431 SCAN, 1 hit
SUPFAMiSSF109640 SSF109640, 1 hit
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS50804 SCAN_BOX, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A087X0J9_HUMAN
AccessioniPrimary (citable) accession number: A0A087X0J9
Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: October 10, 2018
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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