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Protein

Gamma-tubulin complex component

Gene

TUBGCP5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Gamma-tubulin complex componentUniRule annotation
Gene namesi
Name:TUBGCP5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

EuPathDBiHostDB:ENSG00000275835.4
HGNCiHGNC:18600 TUBGCP5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, CytoskeletonUniRule annotation, MicrotubuleUniRule annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000275835

PTM / Processingi

Proteomic databases

PeptideAtlasiA0A087X006

Expressioni

Gene expression databases

BgeeiENSG00000275835 Expressed in 208 organ(s), highest expression level in testis
ExpressionAtlasiA0A087X006 baseline and differential

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the TUBGCP family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00850000132278

Family and domain databases

InterProiView protein in InterPro
IPR007259 GCP
PANTHERiPTHR19302 PTHR19302, 2 hits
PfamiView protein in Pfam
PF04130 Spc97_Spc98, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 14 potential isoforms that are computationally mapped.Show allAlign All

A0A087X006-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XLVEYLQAMR NFFLMEGGDT MYDFYTSIFD KIREKETWQN VSFLNVQLQE
60 70 80 90 100
AVGQRYPEDS SRKWRPGTVA HTCNASTLGG RGGGSPEVRS SRPAWPTCLS
110 120 130 140 150
ISFENVDTAK KKLPVHILDG LTLSYKVPWP VDIVISLECQ KIYNQVFLLL
160 170 180 190 200
LQIKWAKYSL DVLLFGELVS TAEKPRLKEG LIHEQDTVAQ FGPQKEPVRQ
210 220
QIHRMFLLRV KLMHFVNSLH NYIMTR
Length:226
Mass (Da):26,091
Last modified:October 29, 2014 - v1
Checksum:iBC9DCCB84824361D
GO

Computationally mapped potential isoform sequencesi

There are 14 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q96RT8GCP5_HUMAN
Gamma-tubulin complex component 5
TUBGCP5 GCP5, KIAA1899
1,024Annotation score:
A0A087X1Z1A0A087X1Z1_HUMAN
Gamma-tubulin complex component
TUBGCP5
1,026Annotation score:
A0A087WVL9A0A087WVL9_HUMAN
Gamma-tubulin complex component
TUBGCP5
194Annotation score:
A0A087WVZ8A0A087WVZ8_HUMAN
Gamma-tubulin complex component
TUBGCP5
167Annotation score:
A0A0G2JQX1A0A0G2JQX1_HUMAN
Gamma-tubulin complex component
TUBGCP5
1,024Annotation score:
A0A0G2JQI0A0A0G2JQI0_HUMAN
Gamma-tubulin complex component
TUBGCP5
148Annotation score:
A0A0G2JPW5A0A0G2JPW5_HUMAN
Gamma-tubulin complex component
TUBGCP5
1,024Annotation score:
A0A0G2JSA7A0A0G2JSA7_HUMAN
Gamma-tubulin complex component
TUBGCP5
1,026Annotation score:
A0A0G2JQK2A0A0G2JQK2_HUMAN
Gamma-tubulin complex component
TUBGCP5
194Annotation score:
A0A0G2JS51A0A0G2JS51_HUMAN
Gamma-tubulin complex component
TUBGCP5
167Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei226Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC090764 Genomic DNA No translation available.
AC116166 Genomic DNA No translation available.
AC135069 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000610294; ENSP00000483015; ENSG00000275835
ENST00000625857; ENSP00000485682; ENSG00000276856
UCSCiuc059gsf.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC090764 Genomic DNA No translation available.
AC116166 Genomic DNA No translation available.
AC135069 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiA0A087X006

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000610294; ENSP00000483015; ENSG00000275835
ENST00000625857; ENSP00000485682; ENSG00000276856
UCSCiuc059gsf.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000275835.4
HGNCiHGNC:18600 TUBGCP5
OpenTargetsiENSG00000275835
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00850000132278

Miscellaneous databases

ChiTaRSiTUBGCP5 human

Gene expression databases

BgeeiENSG00000275835 Expressed in 208 organ(s), highest expression level in testis
ExpressionAtlasiA0A087X006 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR007259 GCP
PANTHERiPTHR19302 PTHR19302, 2 hits
PfamiView protein in Pfam
PF04130 Spc97_Spc98, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A087X006_HUMAN
AccessioniPrimary (citable) accession number: A0A087X006
Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: September 12, 2018
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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