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Protein
Submitted name:

B-cell CLL/lymphoma 9-like protein

Gene

BCL9L

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
B-cell CLL/lymphoma 9-like proteinImported
Gene namesi
Name:BCL9LImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000186174.12
HGNCiHGNC:23688 BCL9L

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000186174

PTM / Processingi

Proteomic databases

PeptideAtlasiA0A087WZX0
PRIDEiA0A087WZX0

Expressioni

Gene expression databases

BgeeiENSG00000186174
ExpressionAtlasiA0A087WZX0 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliA0A087WZX0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini361 – 393BCL9InterPro annotationAdd BLAST33

Phylogenomic databases

eggNOGiENOG410IEDB Eukaryota
ENOG410XRMX LUCA
GeneTreeiENSGT00730000110915

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR015668 Bcl-9/Bcl-9l
IPR024670 BCL9_beta-catenin-bd_dom
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR15185 PTHR15185, 1 hit
PfamiView protein in Pfam
PF11502 BCL9, 1 hit

Sequencei

Sequence statusi: Complete.

A0A087WZX0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHPENKLTNH GKTGNGGAQS QHQNVNQGPT CNVGSKGVGA GNHGAKANQI
60 70 80 90 100
SPSNSSLKNP QAGVPPFSSL KGKVKRDRSV SVDSGEQREA GTPSLDSEAK
110 120 130 140 150
EVAPRSKRRC VLERKQPYSG DEWCSGPDSE EDDKPIGATH NCNVADPAMA
160 170 180 190 200
APQLGPGQTT QLPLSESSVP GAPHGPPPGL RPDAPGGGGG GGGVPGKPPS
210 220 230 240 250
QFVYVFTTHL ANTAAEAVLQ GRADSILAYH QQNVPRAKLD QAPKVPPTPE
260 270 280 290 300
PLPLSTPSAG TPQSQPPPLP PPPPPAPGSA PPALPPEGPP EDSSQDLAPN
310 320 330 340 350
SVGAASTGGG TGGTHPNTPT ATTANNPLPP GGDPSSAPGP ALLGEAAAPG
360 370 380 390 400
NGQRSLVGSE GLSKEQLEHR ERSLQTLRDI ERLLLRSGET EPFLKGPPGG
410 420 430 440 450
AGEGGPPAQA PPPPQQPPTA PPSGLKKYEE PLQSMISQTQ SLGGPPLEHE
460 470 480 490 500
VPGHPPGGDM GQQMNMMIQR LGQDSLTPEQ VAWRKLQEEY YEEKRRKEEQ
510 520 530 540 550
IGLHGSRPLQ DMMGMGGMMV RGPPPPYHSK PGDQWPPGMG AQLRGPMDVQ
560 570 580 590 600
DPMQLRGGPP FPGPRFPGNQ IQRVPGFGGM QSMPMEVPMN AMQRPVRPGM
610 620 630 640 650
GWTEDLPPMG GPSNFAQNTM PYPGGQGEAE RFMTPRVREE LLRHQLLEKR
660 670 680 690 700
SMGMQRPLGM AGSGMGQSME MERMMQAHRQ MDPAMFPGQM AGGEGLAGTP
710 720 730 740 750
MGMEFGGGRG LLSPPMGQSG LREVDPPMGP GNLNMNMNVN MNMNMNLNVQ
760 770 780 790 800
MTPQQQMLMS QKMRGPGDLM GPQGLSPEEM ARVRAQNSSG VMGGPQKMLM
810 820 830 840 850
PSQFPNQGQQ GFSGGQGPYQ AMSQDMGNTQ DMFSPDQSSM PMSNVGTTRL
860 870 880 890 900
SHMPLPPASN PPGTVHSAPN RGLGRRPSDL TISINQMGSP GMGHLKSPTL
910 920 930 940 950
SQVHSPLVTS PSANLKSPQT PSQMVPLPSA NPPGPLKSPQ VLGSSLSVRS
960 970 980 990 1000
PTGSPSRLKS PSMAVPSPGW VASPKTAMPS PGVSQNKQPP LNMNSSTTLS
1010 1020 1030 1040 1050
NMEQGTLPPS GPRSSSSAPP ANPPSGLMNP SLPFTSSPDP TPSQNPLSLM
1060 1070 1080 1090 1100
MTQMSKYAMP SSTPLYHNAI KTIATSDDEL LPDRPLLPPP PPPQGSGPGI
1110 1120 1130 1140 1150
SNSQPSQMHL NSAAAQSPMG MNLPGQQPLS HEPPPAMLPS PTPLGSNIPL
1160 1170 1180 1190 1200
HPNAQGTGGP PQNSMMMAPG GPDSLNAPCG PVPSSSQMMP FPPRLQQPHG
1210 1220 1230 1240 1250
AMAPTGGGGG GPGLQQHYPS GMALPPEDLP NQPPGPMPPQ QHLMGKAMAG
1260 1270 1280 1290 1300
RMGDAYPPGV LPGVASVLND PELSEVIRPT PTGIPEFDLS RIIPSEKPSS
1310 1320 1330 1340 1350
TLQYFPKSEN QPPKAQPPNL HLMNLQNMMA EQTPSRPPNL PGQQGVQRGL
1360 1370 1380 1390 1400
NMSMCHPGQM SLLGRTGVPP QQGMVPHGLH QGVMSPPQGL MTQQNFMLMK
1410 1420 1430 1440 1450
QRGVGGEVYS QPPHMLSPQG SLMGPPPQQN LMVSHPLRQR SVSLDSQMGY
1460
LPAPGGMANL PF
Length:1,462
Mass (Da):153,087
Last modified:October 29, 2014 - v1
Checksum:iAC6BB84FE844E728
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP004609 Genomic DNA No translation available.
RefSeqiXP_005271569.1, XM_005271512.2
XP_005271570.1, XM_005271513.2
UniGeneiHs.414740

Genome annotation databases

EnsembliENST00000526143; ENSP00000482938; ENSG00000186174
GeneIDi283149
UCSCiuc058ibp.1 human

Similar proteinsi

Entry informationi

Entry nameiA0A087WZX0_HUMAN
AccessioniPrimary (citable) accession number: A0A087WZX0
Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: July 18, 2018
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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