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Entry version 43 (11 Dec 2019)
Sequence version 1 (29 Oct 2014)
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Protein
Submitted name:

Protocadherin-15

Gene

PCDH15

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandCalciumSAAS annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Protocadherin-15Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PCDH15Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000150275.17

Human Gene Nomenclature Database

More...
HGNCi
HGNC:14674 PCDH15

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1387 – 1409HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000150275

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 26Sequence analysisAdd BLAST26
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500183212727 – 1789Sequence analysisAdd BLAST1763

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000150275 Expressed in 67 organ(s), highest expression level in corpus callosum

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A0A087WZW3 baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini69 – 150CAInterPro annotationAdd BLAST82
Domaini179 – 268CAInterPro annotationAdd BLAST90
Domaini309 – 398CAInterPro annotationAdd BLAST90
Domaini431 – 519CAInterPro annotationAdd BLAST89
Domaini543 – 625CAInterPro annotationAdd BLAST83
Domaini650 – 727CAInterPro annotationAdd BLAST78
Domaini751 – 829CAInterPro annotationAdd BLAST79
Domaini853 – 936CAInterPro annotationAdd BLAST84
Domaini960 – 1046CAInterPro annotationAdd BLAST87
Domaini1067 – 1154CAInterPro annotationAdd BLAST88
Domaini1178 – 1262CAInterPro annotationAdd BLAST85

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1587 – 1789DisorderedSequence analysisAdd BLAST203

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1487 – 1507Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1596 – 1652AcidicSequence analysisAdd BLAST57
Compositional biasi1653 – 1696PolyampholyteSequence analysisAdd BLAST44
Compositional biasi1697 – 1722AcidicSequence analysisAdd BLAST26
Compositional biasi1741 – 1758PolarSequence analysisAdd BLAST18
Compositional biasi1767 – 1789PolarSequence analysisAdd BLAST23

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3594 Eukaryota
ENOG410XQHI LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156675

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR020894 Cadherin_CS
IPR041149 EC_dom
IPR030718 Protocadherin-15

The PANTHER Classification System

More...
PANTHERi
PTHR24028:SF11 PTHR24028:SF11, 3 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00028 Cadherin, 8 hits
PF18432 ECD, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00205 CADHERIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00112 CA, 11 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49313 SSF49313, 10 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00232 CADHERIN_1, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 29 potential isoforms that are computationally mapped.Show allAlign All

A0A087WZW3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFRQFYLWTC LASGIILGSL FEICLGQYDD DWQYEDCKLA RGGPPATIVA
60 70 80 90 100
IDEESRNGTI LVDNMLIKGT AGGPDPTIEL SLKDNVDYWV LMDPVKQMLF
110 120 130 140 150
LNSTGRVLDR DPPMNIHSIV VQVQCINKKV GTIIYHEVRI VVRDRNDNSP
160 170 180 190 200
TFKHESYYAT VNELTPVGTT IFTGFSGDNG ATDIDDGPNG QIEYVIQYNP
210 220 230 240 250
DDPTSNDTFE IPLMLTGNIV LRKRLNYEDK TRYFVIIQAN DRAQNLNERR
260 270 280 290 300
TTTTTLTVDV LDGDDLGPMF LPCVLVPNTR DCRPLTYQAA IPELRTPEEL
310 320 330 340 350
NPIIVTPPIQ AIDQDRNIQP PSDRPGILYS ILVGTPEDYP RFFHMHPRTA
360 370 380 390 400
ELSLLEPVNR DFHQKFDLVI KAEQDNGHPL PAFAGLHIEI LDENNQSPYF
410 420 430 440 450
TMPSYQGYIL ESAPVGATIS DSLNLTSPLR IVALDKDIED VPPSGVPTKD
460 470 480 490 500
PELHLFLNDY TSVFTVTQTG ITRYLTLLQP VDREEQQTYT FSITAFDGVQ
510 520 530 540 550
ESEPVIVNIQ VMDANDNTPT FPEISYDVYV YTDMRPGDSV IQLTAVDADE
560 570 580 590 600
GSNGEITYEI LVGAQGDFII NKTTGLITIA PGVEMIVGRT YALTVQAADN
610 620 630 640 650
APPAERRNSI CTVYIEVLPP NNQSPPRFPQ LMYSLEISEA MRVGAVLLNL
660 670 680 690 700
QATDREGDSI TYAIENGDPQ RVFNLSETTG ILTLGKALDR ESTDRYILII
710 720 730 740 750
TASDGRPDGT STATVNIVVT DVNDNAPVFD PYLPRNLSVV EEEANAFVGQ
760 770 780 790 800
VKATDPDAGI NGQVHYSLGN FNNLFRITSN GSIYTAVKLN REVRDYYELV
810 820 830 840 850
VVATDGAVHP RHSTLTLAIK VLDIDDNSPV FTNSTYTVLV EENLPAGTTI
860 870 880 890 900
LQIEAKDVDL GANVSYRIRS PEVKHFFALH PFTGELSLLR SLDYEAFPDQ
910 920 930 940 950
EASITFLVEA FDIYGTMPPG IATVTVIVKD MNDYPPVFSK RIYKGMVAPD
960 970 980 990 1000
AVKGTPITTV YAEDADPPGL PASRVRYRVD DVQFPYPASI FEVEEDSGRV
1010 1020 1030 1040 1050
ITRVNLNEEP TTIFKLVVVA FDDGEPVMSS SATVKILVLH PGEIPRFTQE
1060 1070 1080 1090 1100
EYRPPPVSEL ATKGTMVGVI SAAAINQSIV YSIVSGNEED TFGINNITGV
1110 1120 1130 1140 1150
IYVNGPLDYE TRTSYVLRVQ ADSLEVVLAN LRVPSKSNTA KVYIEIQDEN
1160 1170 1180 1190 1200
NHPPVFQKKF YIGGVSEDAR MFTSVLRVKA TDKDTGNYSV MAYRLIIPPI
1210 1220 1230 1240 1250
KEGKEGFVVE TYTGLIKTAM LFHNMRRSYF KFQVIATDDY GKGLSGKADV
1260 1270 1280 1290 1300
LVSVVNQLDM QVIVSNVPPT LVEKKIEDLT EILDRYVQEQ IPGAKVVVES
1310 1320 1330 1340 1350
IGARRHGDAF SLEDYTKCDL TVYAIDPQTN RAIDRNELFK FLDGKLLDIN
1360 1370 1380 1390 1400
KDFQPYYGEG GRILEIRTPE AVTSIKKRGE SLGYTEGALL ALAFIIILCC
1410 1420 1430 1440 1450
IPAILVVLVS YRQVFKGRQA ECTKTARIQA ALPAAKPAVP APAPVAAPPP
1460 1470 1480 1490 1500
PPPPPPGAHL YEELGDSSMY EMPQYGSRRR LLPPAGQEEY GEVVGEAEEE
1510 1520 1530 1540 1550
YEEEEEEPKK IKKPKVEIRE PSEEEEVVVT IEKPPAAEPT YTTWKRARIF
1560 1570 1580 1590 1600
PMIFKKVRGL ADKRGIVDLE GEEWQRRLEE EDKDYLKLTL DQEEATESTV
1610 1620 1630 1640 1650
ESEEESSSDY TEYSEEESEF SESETTEEES ESETPSEEEE SSTPESEESE
1660 1670 1680 1690 1700
STESEGEKAR KNIVLARRRP MVEEVKEVKG RKEEPQEEQK EPKMEEEEHS
1710 1720 1730 1740 1750
EEEESGPAPV EESTDPEAQD IPEEGSAESA SVEGGVESEE ESESGSSSSS
1760 1770 1780
SESQSGGPWG YQVPAYDRSK NANQKKSPGA NSEGYNTAL
Length:1,789
Mass (Da):198,685
Last modified:October 29, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1745066024D281C0
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 29 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q96QU1PCD15_HUMAN
Protocadherin-15
PCDH15 USH1F
1,955Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A2A3D8A2A3D8_HUMAN
Protocadherin-15
PCDH15
1,962Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WTR6A0A087WTR6_HUMAN
Protocadherin-15
PCDH15
1,539Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WZN9A0A087WZN9_HUMAN
Protocadherin-15
PCDH15
1,790Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087X1T6A0A087X1T6_HUMAN
Protocadherin-15
PCDH15
1,682Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B7ZBT8B7ZBT8_HUMAN
Protocadherin-15
PCDH15
1,150Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8Y6C0A0A2R8Y6C0_HUMAN
Protocadherin-15
PCDH15
1,740Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A2A3E3A2A3E3_HUMAN
Protocadherin-15
PCDH15
1,540Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A2A3E7A2A3E7_HUMAN
Protocadherin-15
PCDH15
1,957Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A2A3E8A2A3E8_HUMAN
Protocadherin-15
PCDH15
1,932Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC013737 Genomic DNA No translation available.
AC016817 Genomic DNA No translation available.
AC024073 Genomic DNA No translation available.
AC027671 Genomic DNA No translation available.
AL353784 Genomic DNA No translation available.
AL360214 Genomic DNA No translation available.
AL365496 Genomic DNA No translation available.
AL391356 Genomic DNA No translation available.
KF455239 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000612394; ENSP00000482921; ENSG00000150275

UCSC genome browser

More...
UCSCi
uc057tik.1 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC013737 Genomic DNA No translation available.
AC016817 Genomic DNA No translation available.
AC024073 Genomic DNA No translation available.
AC027671 Genomic DNA No translation available.
AL353784 Genomic DNA No translation available.
AL360214 Genomic DNA No translation available.
AL365496 Genomic DNA No translation available.
AL391356 Genomic DNA No translation available.
KF455239 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsembliENST00000612394; ENSP00000482921; ENSG00000150275
UCSCiuc057tik.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000150275.17
HGNCiHGNC:14674 PCDH15
OpenTargetsiENSG00000150275

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3594 Eukaryota
ENOG410XQHI LUCA
GeneTreeiENSGT00940000156675

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
PCDH15 human

Gene expression databases

BgeeiENSG00000150275 Expressed in 67 organ(s), highest expression level in corpus callosum
ExpressionAtlasiA0A087WZW3 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR020894 Cadherin_CS
IPR041149 EC_dom
IPR030718 Protocadherin-15
PANTHERiPTHR24028:SF11 PTHR24028:SF11, 3 hits
PfamiView protein in Pfam
PF00028 Cadherin, 8 hits
PF18432 ECD, 1 hit
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 11 hits
SUPFAMiSSF49313 SSF49313, 10 hits
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A087WZW3_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A087WZW3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: December 11, 2019
This is version 43 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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