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Protein
Submitted name:

5-hydroxytryptamine receptor 2A

Gene

HTR2A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
5-hydroxytryptamine receptor 2AImported
Gene namesi
Name:HTR2AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 13

Organism-specific databases

EuPathDBiHostDB:ENSG00000102468.10
HGNCiHGNC:5293 HTR2A

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei45 – 68HelicalSequence analysisAdd BLAST24
Transmembranei80 – 106HelicalSequence analysisAdd BLAST27

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000102468

Expressioni

Gene expression databases

BgeeiENSG00000102468
ExpressionAtlasiA0A087WZJ9 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A087WZJ9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini60 – 110G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST51

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
GeneTreeiENSGT00890000139331

Family and domain databases

InterProiView protein in InterPro
IPR000455 5HT2A_rcpt
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PANTHERiPTHR24247:SF30 PTHR24247:SF30, 1 hit
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00516 5HT2ARECEPTR
PR00237 GPCRRHODOPSN
PROSITEiView protein in PROSITE
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Fragment.

A0A087WZJ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
FNSGEANTSD AFNWTVDSEN RTNLSCEGCL SPSCLSLLHL QEKNWSALLT
60 70 80 90 100
AVVIILTIAG NILVIMAVSL EKKLQNATNY FLMSLAIADM LLGFLVMPVS
110
MLTILYGEWH
Length:110
Mass (Da):12,096
Last modified:October 29, 2014 - v1
Checksum:i7428BC46F5DB383C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL136958 Genomic DNA No translation available.
AL160397 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000612998; ENSP00000482708; ENSG00000102468
UCSCiuc058wxl.1 human

Similar proteinsi

Entry informationi

Entry nameiA0A087WZJ9_HUMAN
AccessioniPrimary (citable) accession number: A0A087WZJ9
Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: May 23, 2018
This is version 20 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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