Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Suppressor of cytokine-signaling 7

Gene

SOCS7

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
Suppressor of cytokine-signaling 7Imported
Gene namesi
Name:SOCS7Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000274211.4
HGNCiHGNC:29846 SOCS7

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000274211

PTM / Processingi

Proteomic databases

PeptideAtlasiA0A087WZ14

Expressioni

Gene expression databases

BgeeiENSG00000274211 Expressed in 210 organ(s), highest expression level in secondary oocyte
ExpressionAtlasiA0A087WZ14 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini99 – 152SH2InterPro annotationAdd BLAST54

Keywords - Domaini

SH2 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4566 Eukaryota
ENOG4111V4J LUCA
GeneTreeiENSGT00760000119136

Family and domain databases

Gene3Di3.30.505.10, 1 hit
InterProiView protein in InterPro
IPR000980 SH2
IPR036860 SH2_dom_sf
IPR028423 SOCS7
PANTHERiPTHR45052 PTHR45052, 2 hits
PfamiView protein in Pfam
PF00017 SH2, 1 hit
SMARTiView protein in SMART
SM00252 SH2, 1 hit
SUPFAMiSSF55550 SSF55550, 1 hit
PROSITEiView protein in PROSITE
PS50001 SH2, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

A0A087WZ14-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XGKRPSGELA ASAASLTDMG GSAGRELDAG RKPKLTRTQS AFSPVSFSPL
60 70 80 90 100
FTDAFPRIAP IRAAESLHSQ PPQHLQCPLY RPDSSSFAAS LRELEKCGWY
110 120 130 140 150
WGPMNWEDAE MKLKGKPDGS FLVRDSSDPR YILSLSFRSQ GITHHTRMEH
160
YRGTFSLWCH
Length:160
Mass (Da):17,824
Last modified:October 5, 2016 - v6
Checksum:i90EB1CCC2CF7B834
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O14512SOCS7_HUMAN
Suppressor of cytokine signaling 7
SOCS7 NAP4, SOCS6
581Annotation score:
A0A087X1Q5A0A087X1Q5_HUMAN
Suppressor of cytokine-signaling 7
SOCS7
547Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei160Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124789 Genomic DNA No translation available.
AC183084 Genomic DNA No translation available.
AC244092 Genomic DNA No translation available.
AC244153 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000617765; ENSP00000482278; ENSG00000274211
ENST00000632687; ENSP00000487855; ENSG00000274229
UCSCiuc060elv.1 human

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124789 Genomic DNA No translation available.
AC183084 Genomic DNA No translation available.
AC244092 Genomic DNA No translation available.
AC244153 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiA0A087WZ14

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000617765; ENSP00000482278; ENSG00000274211
ENST00000632687; ENSP00000487855; ENSG00000274229
UCSCiuc060elv.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000274211.4
HGNCiHGNC:29846 SOCS7
OpenTargetsiENSG00000274211
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4566 Eukaryota
ENOG4111V4J LUCA
GeneTreeiENSGT00760000119136

Miscellaneous databases

ChiTaRSiSOCS7 human

Gene expression databases

BgeeiENSG00000274211 Expressed in 210 organ(s), highest expression level in secondary oocyte
ExpressionAtlasiA0A087WZ14 baseline and differential

Family and domain databases

Gene3Di3.30.505.10, 1 hit
InterProiView protein in InterPro
IPR000980 SH2
IPR036860 SH2_dom_sf
IPR028423 SOCS7
PANTHERiPTHR45052 PTHR45052, 2 hits
PfamiView protein in Pfam
PF00017 SH2, 1 hit
SMARTiView protein in SMART
SM00252 SH2, 1 hit
SUPFAMiSSF55550 SSF55550, 1 hit
PROSITEiView protein in PROSITE
PS50001 SH2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A087WZ14_HUMAN
AccessioniPrimary (citable) accession number: A0A087WZ14
Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 5, 2016
Last modified: September 12, 2018
This is version 31 of the entry and version 6 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again