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Protein
Submitted name:

Tetraspanin-6

Gene

TSPAN6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Tetraspanin-6Imported
Gene namesi
Name:TSPAN6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000000003.14
HGNCiHGNC:11858 TSPAN6

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 26HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000000003

PTM / Processingi

Proteomic databases

PeptideAtlasiA0A087WYV6
PRIDEiA0A087WYV6

Expressioni

Gene expression databases

BgeeiENSG00000000003 Expressed in 219 organ(s), highest expression level in sperm
ExpressionAtlasiA0A087WYV6 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A087WYV6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tetraspanin (TM4SF) family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00880000137851

Family and domain databases

Gene3Di1.10.1450.10, 1 hit
InterProiView protein in InterPro
IPR018499 Tetraspanin/Peripherin
IPR008952 Tetraspanin_EC2_sf
PfamiView protein in Pfam
PF00335 Tetraspannin, 1 hit
SUPFAMiSSF48652 SSF48652, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.iShow all

A0A087WYV6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLKLYAMFLT LVFLVELVAA IVGFVFRHEI KNSFKNNYEK ALKQYNSTGD
60 70 80 90 100
YRSHAVDKIQ NTLHCCGVTD YRDWTDTNYY SEKGFPKSCC KLEDCTPQRD
110 120
ADKVNNELIG IFLAYCLSRA ITNNQYEIV
Length:129
Mass (Da):14,958
Last modified:October 29, 2014 - v1
Checksum:iA91152BDA837BB74
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O43657TSN6_HUMAN
Tetraspanin-6
TSPAN6 TM4SF6, UNQ767/PRO1560
245Annotation score:
A0A087WZU5A0A087WZU5_HUMAN
Tetraspanin-6
TSPAN6
137Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL035608 Genomic DNA No translation available.
RefSeqiNP_001265672.1, NM_001278743.1
UniGeneiHs.43233
Hs.587521

Genome annotation databases

EnsembliENST00000612152; ENSP00000482130; ENSG00000000003
GeneIDi7105
UCSCiuc033eom.2 human

Similar proteinsi

Entry informationi

Entry nameiA0A087WYV6_HUMAN
AccessioniPrimary (citable) accession number: A0A087WYV6
Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: September 12, 2018
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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