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UniProtKB - A0A087WXM8 (A0A087WXM8_HUMAN)
Protein
Submitted name:
Basal cell adhesion molecule
Gene
BCAM
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Basal cell adhesion molecule |
Gene namesi | Name:BCAM |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:6722, BCAM |
VEuPathDBi | HostDB:ENSG00000187244 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 549 – 571 | HelicalSequence analysisAdd BLAST | 23 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 31 | Sequence analysisAdd BLAST | 31 | |
ChainiPRO_5030002789 | 32 – 588 | Sequence analysisAdd BLAST | 557 |
Proteomic databases
MaxQBi | A0A087WXM8 |
PeptideAtlasi | A0A087WXM8 |
Expressioni
Gene expression databases
Bgeei | ENSG00000187244, Expressed in adult mammalian kidney and 210 other tissues |
ExpressionAtlasi | A0A087WXM8, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 27 – 142 | Ig-likeInterPro annotationAdd BLAST | 116 | |
Domaini | 147 – 257 | Ig-likeInterPro annotationAdd BLAST | 111 | |
Domaini | 274 – 355 | Ig-likeInterPro annotationAdd BLAST | 82 | |
Domaini | 363 – 441 | Ig-likeInterPro annotationAdd BLAST | 79 | |
Domaini | 448 – 541 | Ig-likeInterPro annotationAdd BLAST | 94 |
Keywords - Domaini
SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000161038 |
OMAi | CCRRREK |
Family and domain databases
Gene3Di | 2.60.40.10, 5 hits |
InterProi | View protein in InterPro IPR013162, CD80_C2-set IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003599, Ig_sub IPR003598, Ig_sub2 IPR013106, Ig_V-set |
Pfami | View protein in Pfam PF08205, C2-set_2, 1 hit PF13895, Ig_2, 2 hits PF07686, V-set, 1 hit |
SMARTi | View protein in SMART SM00409, IG, 5 hits SM00408, IGc2, 3 hits |
SUPFAMi | SSF48726, SSF48726, 5 hits |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 5 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
A0A087WXM8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEPPDAPAQA RGAPRLLLLA VLLAAHPDAQ AEVRLSVPPL VEVMRGKSVI
60 70 80 90 100
LDCTPTGTHD HYMLEWFLTD RSGARPRLAS AEMQGSELQV TMHDTRGRSP
110 120 130 140 150
PYQLDSQGRL VLAEAQVGDE RDYVCVVRAG AAGTAEATAR LNVFAKPEAT
160 170 180 190 200
EVSPNKGTLS VMEDSAQEIA TCNSRNGNPA PKITWYRNGQ RLEVPVEMNP
210 220 230 240 250
EGYMTSRTVR EASGLLSLTS TLYLRLRKDD RDASFHCAAH YSLPEGRHGR
260 270 280 290 300
LDSPTFHLTL HYPTEHVQFW VGSPSTPAGW VREGDTVQLL CRGDGSPSPE
310 320 330 340 350
YTLFRLQDEQ EEVLNVNLEG NLTLEGVTRG QSGTYGCRVE DYDAADDVQL
360 370 380 390 400
SKTLELRVAY LDPLELSEGK VLSLPLNSSA VVNCSVHGLP TPALRWTKDS
410 420 430 440 450
TPLGDGPMLS LSSITFDSNG TYVCEASLPT VPVLSRTQNF TLLVQGSPEL
460 470 480 490 500
KTAEIEPKAD GSWREGDEVT LICSARGHPD PKLSWSQLGG SPAEPIPGRQ
510 520 530 540 550
GWVSSSLTLK VTSALSRDGI SCEASNPHGN KRHVFHFGTV SPQTSQAGVA
560 570 580
VMAVAVSVGL LLLVVAVFYC VRRKGGPCCR QRREKGAP
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP50895 | BCAM_HUMAN | Basal cell adhesion molecule | BCAM LU, MSK19 | 628 | Annotation score: | ||
K7ENU8 | K7ENU8_HUMAN | Basal cell adhesion molecule | BCAM | 286 | Annotation score: | ||
K7ERB7 | K7ERB7_HUMAN | Basal cell adhesion molecule | BCAM | 61 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC092306 Genomic DNA No translation available. |
RefSeqi | NP_001013275.1, NM_001013257.2 |
Genome annotation databases
Ensembli | ENST00000611077.5; ENSP00000481153.1; ENSG00000187244.12 |
GeneIDi | 4059 |
UCSCi | uc002ozt.3, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC092306 Genomic DNA No translation available. |
RefSeqi | NP_001013275.1, NM_001013257.2 |
3D structure databases
SMRi | A0A087WXM8 |
ModBasei | Search... |
Proteomic databases
MaxQBi | A0A087WXM8 |
PeptideAtlasi | A0A087WXM8 |
Protocols and materials databases
Antibodypediai | 17750, 424 antibodies from 35 providers |
DNASUi | 4059 |
Genome annotation databases
Ensembli | ENST00000611077.5; ENSP00000481153.1; ENSG00000187244.12 |
GeneIDi | 4059 |
UCSCi | uc002ozt.3, human |
Organism-specific databases
CTDi | 4059 |
HGNCi | HGNC:6722, BCAM |
OpenTargetsi | ENSG00000187244 |
VEuPathDBi | HostDB:ENSG00000187244 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000161038 |
OMAi | CCRRREK |
Miscellaneous databases
BioGRID-ORCSi | 4059, 17 hits in 1075 CRISPR screens |
ChiTaRSi | BCAM, human |
GenomeRNAii | 4059 |
Gene expression databases
Bgeei | ENSG00000187244, Expressed in adult mammalian kidney and 210 other tissues |
ExpressionAtlasi | A0A087WXM8, baseline and differential |
Family and domain databases
Gene3Di | 2.60.40.10, 5 hits |
InterProi | View protein in InterPro IPR013162, CD80_C2-set IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003599, Ig_sub IPR003598, Ig_sub2 IPR013106, Ig_V-set |
Pfami | View protein in Pfam PF08205, C2-set_2, 1 hit PF13895, Ig_2, 2 hits PF07686, V-set, 1 hit |
SMARTi | View protein in SMART SM00409, IG, 5 hits SM00408, IGc2, 3 hits |
SUPFAMi | SSF48726, SSF48726, 5 hits |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 5 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A087WXM8_HUMAN | |
Accessioni | A0A087WXM8Primary (citable) accession number: A0A087WXM8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 29, 2014 |
Last sequence update: | October 29, 2014 | |
Last modified: | May 25, 2022 | |
This is version 56 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |