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Protein
Submitted name:

Importin-8

Gene

IPO8

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Importin-8Imported
Gene namesi
Name:IPO8Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000133704.9
HGNCiHGNC:9853 IPO8

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000133704

PTM / Processingi

Proteomic databases

PeptideAtlasiA0A087WXH2

Expressioni

Gene expression databases

BgeeiENSG00000133704 Expressed in 206 organ(s), highest expression level in secondary oocyte
ExpressionAtlasiA0A087WXH2 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A087WXH2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG1991 Eukaryota
COG5656 LUCA
GeneTreeiENSGT00550000074736

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
SUPFAMiSSF48371 SSF48371, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

A0A087WXH2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XVQLTMCLRA IIKHDFPGHW PGVVDKIDYY LQSQSSASWL GSLLCLYQLV
60 70 80 90 100
KTYEYKKAEE REPLIIAMQI FLPRIQQQIV QLLPDSSYYS VLLQKQILKI
110 120 130 140
FYALVQVGFY CRKQTWSPVF LPDTWKVLNK CHLLLKIILY YP
Length:142
Mass (Da):16,785
Last modified:October 29, 2014 - v1
Checksum:i547953706184E2AE
GO

Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O15397IPO8_HUMAN
Importin-8
IPO8 RANBP8
1,037Annotation score:
F5H292F5H292_HUMAN
Importin-8
IPO8
84Annotation score:
F5GXT5F5GXT5_HUMAN
Importin-8
IPO8
151Annotation score:
F5H2I3F5H2I3_HUMAN
Importin-8
IPO8
46Annotation score:
F5H244F5H244_HUMAN
Importin-8
IPO8
167Annotation score:
H0YH64H0YH64_HUMAN
Importin-8
IPO8
167Annotation score:
F5H815F5H815_HUMAN
Importin-8
IPO8
35Annotation score:
F5H009F5H009_HUMAN
Importin-8
IPO8
33Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC012673 Genomic DNA No translation available.
AC023426 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000611458; ENSP00000481026; ENSG00000133704
UCSCiuc058mjq.1 human

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC012673 Genomic DNA No translation available.
AC023426 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliA0A087WXH2
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiA0A087WXH2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000611458; ENSP00000481026; ENSG00000133704
UCSCiuc058mjq.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000133704.9
HGNCiHGNC:9853 IPO8
OpenTargetsiENSG00000133704
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1991 Eukaryota
COG5656 LUCA
GeneTreeiENSGT00550000074736

Miscellaneous databases

ChiTaRSiIPO8 human

Gene expression databases

BgeeiENSG00000133704 Expressed in 206 organ(s), highest expression level in secondary oocyte
ExpressionAtlasiA0A087WXH2 baseline and differential

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
SUPFAMiSSF48371 SSF48371, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A087WXH2_HUMAN
AccessioniPrimary (citable) accession number: A0A087WXH2
Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: September 12, 2018
This is version 21 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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