UniProtKB - A0A087WWD6 (A0A087WWD6_HUMAN)
Protein
Submitted name:
Receptor-type tyrosine-protein phosphatase T
Gene
PTPRT
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Receptor-type tyrosine-protein phosphatase TImported |
Gene namesi | Name:PTPRTImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:9682, PTPRT |
VEuPathDBi | HostDB:ENSG00000196090.12 |
Subcellular locationi
Other locations
- membrane Source: InterPro
Expressioni
Gene expression databases
Bgeei | ENSG00000196090, Expressed in middle temporal gyrus and 108 other tissues |
ExpressionAtlasi | A0A087WWD6, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 120 | MAMInterPro annotationAdd BLAST | 120 | |
Domaini | 122 – 213 | Ig-likeInterPro annotationAdd BLAST | 92 | |
Domaini | 220 – 313 | Fibronectin type-IIIInterPro annotationAdd BLAST | 94 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 293 – 313 | DisorderedSequence analysisAdd BLAST | 21 |
Keywords - Domaini
Immunoglobulin domainARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000155326 |
HOGENOMi | CLU_066569_0_0_1 |
Family and domain databases
CDDi | cd00063, FN3, 1 hit cd06263, MAM, 1 hit |
Gene3Di | 2.60.40.10, 2 hits |
InterProi | View protein in InterPro IPR013320, ConA-like_dom_sf IPR003961, FN3_dom IPR036116, FN3_sf IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR000998, MAM_dom |
Pfami | View protein in Pfam PF00041, fn3, 1 hit PF00629, MAM, 1 hit |
PRINTSi | PR00020, MAMDOMAIN |
SMARTi | View protein in SMART SM00060, FN3, 1 hit SM00137, MAM, 1 hit |
SUPFAMi | SSF48726, SSF48726, 1 hit SSF49265, SSF49265, 1 hit SSF49899, SSF49899, 1 hit |
PROSITEi | View protein in PROSITE PS50853, FN3, 1 hit PS50835, IG_LIKE, 1 hit PS00740, MAM_1, 1 hit PS50060, MAM_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All
A0A087WWD6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
GSFMMVNSSG RASGQKAHLL LPTLKENDTH CIDFHYYFSS RDRSSPGALN
60 70 80 90 100
VYVKVNGGPQ GNPVWNVSGV VTEGWVKAEL AISTFWPHFY QVIFESVSLK
110 120 130 140 150
GHPGYIAVDE VRVLAHPCRK APHFLRLQNV EVNVGQNATF QCIAGGKWSQ
160 170 180 190 200
HDKLWLQQWN GRDTALMVTR VVNHRRFSAT VSVADTAQRS VSKYRCVIRS
210 220 230 240 250
DGGSGVSNYA ELIVKEPPTP IAPPELLAVG ATYLWIKPNA NSIIGDGPII
260 270 280 290 300
LKEVEYRTTT GTWAETHIVD SPNYKLWHLD PDVEYEIRVL LTRPGEGGTG
310
PPGPPLTTRT KCA
Computationally mapped potential isoform sequencesi
There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketO14522 | PTPRT_HUMAN | Receptor-type tyrosine-protein phos... | PTPRT KIAA0283 | 1,441 | Annotation score: | ||
B1AJR9 | B1AJR9_HUMAN | Protein-tyrosine-phosphatase | PTPRT | 1,451 | Annotation score: | ||
B1AJS0 | B1AJS0_HUMAN | Protein-tyrosine-phosphatase | PTPRT | 1,431 | Annotation score: | ||
B1AJR8 | B1AJR8_HUMAN | Protein-tyrosine-phosphatase | PTPRT | 1,450 | Annotation score: | ||
A0A075B6H0 | A0A075B6H0_HUMAN | Protein-tyrosine-phosphatase | PTPRT | 1,460 | Annotation score: | ||
B1AJR6 | B1AJR6_HUMAN | Protein-tyrosine-phosphatase | PTPRT | 1,440 | Annotation score: | ||
A0A087WY22 | A0A087WY22_HUMAN | Protein-tyrosine-phosphatase | PTPRT | 1,059 | Annotation score: | ||
A0A087X1X2 | A0A087X1X2_HUMAN | Protein-tyrosine-phosphatase | PTPRT | 1,076 | Annotation score: | ||
A0A087X1J1 | A0A087X1J1_HUMAN | Receptor-type tyrosine-protein phos... | PTPRT | 47 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL022239 Genomic DNA No translation available. AL024473 Genomic DNA No translation available. AL035459 Genomic DNA No translation available. AL049812 Genomic DNA No translation available. AL109826 Genomic DNA No translation available. KF456906 Genomic DNA No translation available. KF456910 Genomic DNA No translation available. Z93942 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000620410; ENSP00000480136; ENSG00000196090 |
UCSCi | uc061xch.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL022239 Genomic DNA No translation available. AL024473 Genomic DNA No translation available. AL035459 Genomic DNA No translation available. AL049812 Genomic DNA No translation available. AL109826 Genomic DNA No translation available. KF456906 Genomic DNA No translation available. KF456910 Genomic DNA No translation available. Z93942 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | A0A087WWD6 |
Protocols and materials databases
Antibodypediai | 2780, 107 antibodies |
Genome annotation databases
Ensembli | ENST00000620410; ENSP00000480136; ENSG00000196090 |
UCSCi | uc061xch.1, human |
Organism-specific databases
HGNCi | HGNC:9682, PTPRT |
OpenTargetsi | ENSG00000196090 |
VEuPathDBi | HostDB:ENSG00000196090.12 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000155326 |
HOGENOMi | CLU_066569_0_0_1 |
Miscellaneous databases
ChiTaRSi | PTPRT, human |
Gene expression databases
Bgeei | ENSG00000196090, Expressed in middle temporal gyrus and 108 other tissues |
ExpressionAtlasi | A0A087WWD6, baseline and differential |
Family and domain databases
CDDi | cd00063, FN3, 1 hit cd06263, MAM, 1 hit |
Gene3Di | 2.60.40.10, 2 hits |
InterProi | View protein in InterPro IPR013320, ConA-like_dom_sf IPR003961, FN3_dom IPR036116, FN3_sf IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR000998, MAM_dom |
Pfami | View protein in Pfam PF00041, fn3, 1 hit PF00629, MAM, 1 hit |
PRINTSi | PR00020, MAMDOMAIN |
SMARTi | View protein in SMART SM00060, FN3, 1 hit SM00137, MAM, 1 hit |
SUPFAMi | SSF48726, SSF48726, 1 hit SSF49265, SSF49265, 1 hit SSF49899, SSF49899, 1 hit |
PROSITEi | View protein in PROSITE PS50853, FN3, 1 hit PS50835, IG_LIKE, 1 hit PS00740, MAM_1, 1 hit PS50060, MAM_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A087WWD6_HUMAN | |
Accessioni | A0A087WWD6Primary (citable) accession number: A0A087WWD6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 29, 2014 |
Last sequence update: | October 29, 2014 | |
Last modified: | February 10, 2021 | |
This is version 34 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |