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Protein
Submitted name:

Tetratricopeptide repeat protein 28

Gene

TTC28

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Tetratricopeptide repeat protein 28Imported
Gene namesi
Name:TTC28Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 22

Organism-specific databases

EuPathDBiHostDB:ENSG00000100154.14
HGNCiHGNC:29179 TTC28

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000100154

PTM / Processingi

Proteomic databases

EPDiA0A087WW06
PeptideAtlasiA0A087WW06

Expressioni

Gene expression databases

BgeeiENSG00000100154
ExpressionAtlasiA0A087WW06 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A087WW06
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 1023TPR_REGIONInterPro annotationAdd BLAST1023
Repeati1 – 32TPRPROSITE-ProRule annotationAdd BLAST32
Repeati147 – 180TPRPROSITE-ProRule annotationAdd BLAST34
Repeati187 – 220TPRPROSITE-ProRule annotationAdd BLAST34
Repeati227 – 260TPRPROSITE-ProRule annotationAdd BLAST34
Repeati267 – 300TPRPROSITE-ProRule annotationAdd BLAST34
Repeati307 – 340TPRPROSITE-ProRule annotationAdd BLAST34
Repeati347 – 380TPRPROSITE-ProRule annotationAdd BLAST34
Repeati387 – 420TPRPROSITE-ProRule annotationAdd BLAST34
Repeati427 – 460TPRPROSITE-ProRule annotationAdd BLAST34
Repeati467 – 500TPRPROSITE-ProRule annotationAdd BLAST34
Repeati507 – 540TPRPROSITE-ProRule annotationAdd BLAST34
Repeati547 – 580TPRPROSITE-ProRule annotationAdd BLAST34
Repeati587 – 620TPRPROSITE-ProRule annotationAdd BLAST34
Repeati627 – 660TPRPROSITE-ProRule annotationAdd BLAST34
Repeati667 – 700TPRPROSITE-ProRule annotationAdd BLAST34
Repeati707 – 740TPRPROSITE-ProRule annotationAdd BLAST34
Repeati750 – 783TPRPROSITE-ProRule annotationAdd BLAST34
Repeati790 – 823TPRPROSITE-ProRule annotationAdd BLAST34
Repeati830 – 863TPRPROSITE-ProRule annotationAdd BLAST34
Repeati870 – 903TPRPROSITE-ProRule annotationAdd BLAST34
Repeati910 – 943TPRPROSITE-ProRule annotationAdd BLAST34
Repeati950 – 983TPRPROSITE-ProRule annotationAdd BLAST34
Repeati990 – 1023TPRPROSITE-ProRule annotationAdd BLAST34

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili320 – 340Sequence analysisAdd BLAST21
Coiled coili843 – 870Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, TPR repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0548 Eukaryota
KOG1130 Eukaryota
COG0457 LUCA
COG4995 LUCA
ENOG410XP6N LUCA
GeneTreeiENSGT00530000063126

Family and domain databases

Gene3Di1.25.40.10, 5 hits
InterProiView protein in InterPro
IPR024983 CHAT_dom
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PfamiView protein in Pfam
PF12770 CHAT, 1 hit
PF13176 TPR_7, 1 hit
PF13181 TPR_8, 1 hit
SMARTiView protein in SMART
SM00028 TPR, 23 hits
SUPFAMiSSF48452 SSF48452, 7 hits
PROSITEiView protein in PROSITE
PS50005 TPR, 23 hits
PS50293 TPR_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

A0A087WW06-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
AYFRQGVALQ YLGRHADALA AFASGLAQDP KSLQLLVGMV EAAMKSPMRD
60 70 80 90 100
SLEPTYQQLQ KMKLDKSPFV VVSVVGQELL TAGHHGASVV VLEAALKIGT
110 120 130 140 150
CSLKLRGSVF SALSSAYWSL GNTEKSTGYM QQDLDVAKTL GDQTGECRAH
160 170 180 190 200
GNLGSAFFSK GNYREALTNH RHQLVLAMKL KDREAASSAL SSLGHVYTAI
210 220 230 240 250
GDYPNALASH KQCVLLAKQS KDELSEAREL GNMGAVYIAM GDFENAVQCH
260 270 280 290 300
EQHLKIAKDL GNKREEARAY SNLGSAYHYR RNFDKAMSYH NYVLELAQEL
310 320 330 340 350
MEKAIEMRAY AGLGHAARCM QDLERAKQYH EQQLGIAEDL KDRAAEGRAS
360 370 380 390 400
SNLGIIHQMK GDYDTALKLH KTHLCIAQEL SDYAAQGRAY GNMGNAYNAL
410 420 430 440 450
GMYDQAVKYH RQELQISMEV NDRASQASTH GNLAVAYQAL GAHDRALQHY
460 470 480 490 500
QNHLNIAREL RDIQSEARAL SNLGNFHCSR GEYVQAAPYY EQYLRLAPDL
510 520 530 540 550
QDMEGEGKVC HNLGYAHYCL GNYQEAVKYY EQDLALAKDL HDKLSQAKAY
560 570 580 590 600
CNLGLAFKAL LNFSKAEECQ KYLLSLAQSL NNSQAKFRAL GNLGDIFICK
610 620 630 640 650
KDINGAIKFY EQQLGLAHQV KDRRLEASAY AALGTAYRMI QKYDKALGYH
660 670 680 690 700
TQELEVYQEL SDLPGECRAH GHLAAVYMAL GKYTMAFKCY EEQLDLGQKL
710 720 730 740 750
KDPSLEAQVY GNMGITKMNM NVMEEAIGYF EQQLAMLQQL SGNESVLDRG
760 770 780 790 800
RAYGNLGDCY EALGDYEEAI KYYEQYLSVA QSLNRMQDQA KAYRGLGNGH
810 820 830 840 850
RAMGSLQQAL VCFEKRLVVA HELGEAFNKA QAYGELGSLH SQLGNYEQAI
860 870 880 890 900
SCLERQLNIA RDMKDRALES DAACGLGGVY QQMGEYDTAL QYHQLDLQIA
910 920 930 940 950
EETNNPTCQG RAYGNLGLTY ESLGTFERAV VYQEQHLSIA AQMNDLAAKT
960 970 980 990 1000
VSYSSLGRTH HALQNYSQAV MYLQEGLRLA EQLGRREDEA KIRHGLGLSL
1010 1020 1030 1040 1050
WASGNLEEAQ HQLYRASALF ETIRHEAQLS TDYKLSLFDL QTSSYQALQR
1060 1070 1080 1090 1100
VLVSLGHHDE ALAVAERGRT RAFADLLVER QTGQQDSDPY SPVTIDQILE
1110 1120 1130 1140 1150
MVNGQRGLVL YYSLAAGYLY SWLLAPGAGI VKFHEHYLGE NTVENSSDFQ
1160 1170 1180 1190 1200
ASSSVTLPTA TGSALEQHIA SVREALGVES HYSRACASSE TESEAGDIMD
1210 1220 1230 1240 1250
QQFEEMNNKL NSVTDPTGFL RMVRRNNLFN RSCQSMTSLF SNTVSPTQDG
1260 1270 1280 1290 1300
TSSLPRRQSS FAKPPLRALY DLLIAPMEGG LMHSSGPVGR HRQLILVLEG
1310 1320 1330 1340 1350
ELYLIPFALL KGSSSNEYLY ERFGLLAVPS IRSLSVQSKS HLRKNPPTYS
1360 1370 1380 1390 1400
SSTSMAAVIG NPKLPSAVMD RWLWGPMPSA EEEAYMVSEL LGCQPLVGSV
1410 1420 1430 1440 1450
ATKERVMSAL TQAECVHFAT HISWKLSALV LTPSMDGNPA SSKSSFGHPY
1460 1470 1480 1490 1500
TIPESLRVQD DASDGESISD CPPLQELLLT AADVLDLQLP VKLVVLGSSQ
1510 1520 1530 1540 1550
ESNSKVTADG VIALTRAFLA AGAQCVLVSL WPVPVAASKM FIHAFYSSLL
1560 1570 1580 1590 1600
NGLKASAALG EAMKVVQSSK AFSHPSNWAG FMLIGSDVKL NSPSSLIGQA
1610 1620 1630 1640 1650
LTEILQHPER ARDALRVLLH LVEKSLQRIQ NGQRNAMYTS QQSVENKVGG
1660 1670 1680 1690 1700
IPGWQALLTA VGFRLDPPTS GLPAAVFFPT SDPGDRLQQC SSTLQSLLGL
1710 1720 1730 1740 1750
PNPALQALCK LITASETGEQ LISRAVKNMV GMLHQVLVQL QAGEKEQDLA
1760 1770 1780 1790 1800
SAPIQVSISV QLWRLPGCHE FLAALGFDLC EVGQEEVILK TGKQANRRTV
1810 1820 1830 1840 1850
HFALQSLLSL FDSTELPKRL SLDSSSSLES LASAQSVSNA LPLGYQQPPF
1860 1870 1880 1890 1900
SPTGADSIAS DAISVYSLSS IASSMSFVSK PEGGSEGGGP GGRQDHDRSK
1910 1920 1930 1940 1950
NAYLQRSTLP RSQLPPQTRP AGNKDEEEYE GFSIISNEPL ATYQENRNTC
1960 1970 1980 1990 2000
FSPDHKQPQP GTAGGMRVSV SSKGSISTPN SPVKMTLIPS PNSPFQKVGK
2010 2020 2030 2040 2050
LASSDTGESD QSSTETDSTV KSQEESNPKL DPQELAQKIL EETQSHLIAV
2060 2070 2080 2090 2100
ERLQRSGGQV SKSNNPEDGV QAPSSTAVFR ASETSAFSRP VLSHQKSQPS
2110 2120 2130 2140 2150
PVTVKPKPPA RSSSLPKVSS GYSSPTTSEM SIKDSPSQHS GRPSPGCDSQ
2160 2170 2180 2190 2200
TSQLDQPLFK LKYPSSPYSA HISKSPRNMS PSSGHQSPAG SAPSPALSYS
2210 2220 2230 2240 2250
SAGSARSSPA DAPDIDKLKM AAIDEKVQAV HNLKMFWQST PQHSTGPMKI
2260 2270 2280 2290 2300
FRGAPGTMTS KRDVLSLLNL SPRHNKKEEG VDKLELKELS LQQHDGAPPK
2310 2320 2330 2340 2350
APPNGHWRTE TTSLGSLPLP AGPPATAPAR PLRLPSGNGY KFLSPGRFFP

SSKC
Length:2,354
Mass (Da):256,868
Last modified:October 29, 2014 - v1
Checksum:iA8F6AEE9642DCC0E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL008722 Genomic DNA No translation available.
AL023281 Genomic DNA No translation available.
AL033538 Genomic DNA No translation available.
AL035397 Genomic DNA No translation available.
AL035453 Genomic DNA No translation available.
AL050313 Genomic DNA No translation available.
AL080241 Genomic DNA No translation available.
AL118497 Genomic DNA No translation available.
KF457393 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000612946; ENSP00000479834; ENSG00000100154
UCSCiuc062ctm.1 human

Similar proteinsi

Entry informationi

Entry nameiA0A087WW06_HUMAN
AccessioniPrimary (citable) accession number: A0A087WW06
Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: June 20, 2018
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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