UniProtKB - A0A087WVC2 (A0A087WVC2_HUMAN)
Protein
Submitted name:
Ankyrin-3
Gene
ANK3
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Ankyrin-3Imported |
Gene namesi | Name:ANK3Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000151150.20 |
HGNCi | HGNC:494, ANK3 |
Expressioni
Gene expression databases
Bgeei | ENSG00000151150, Expressed in substantia nigra and 246 other tissues |
ExpressionAtlasi | A0A087WVC2, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 171 – 255 | DeathInterPro annotationAdd BLAST | 85 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 45 | DisorderedSequence analysisAdd BLAST | 45 | |
Regioni | 63 – 134 | DisorderedSequence analysisAdd BLAST | 72 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 23 | PolyampholyteSequence analysisAdd BLAST | 23 | |
Compositional biasi | 73 – 97 | PolyampholyteSequence analysisAdd BLAST | 25 | |
Compositional biasi | 104 – 127 | PolarSequence analysisAdd BLAST | 24 |
Phylogenomic databases
GeneTreei | ENSGT00940000154939 |
HOGENOMi | CLU_867523_0_0_1 |
Family and domain databases
CDDi | cd08803, Death_ank3, 1 hit |
InterProi | View protein in InterPro IPR037971, Ank3_Death IPR011029, DEATH-like_dom_sf IPR000488, Death_domain |
Pfami | View protein in Pfam PF00531, Death, 1 hit |
SMARTi | View protein in SMART SM00005, DEATH, 1 hit |
SUPFAMi | SSF47986, SSF47986, 1 hit |
PROSITEi | View protein in PROSITE PS50017, DEATH_DOMAIN, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 22 potential isoforms that are computationally mapped.Show allAlign All
A0A087WVC2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
XGPDEDKPPS KSSSSEKTPD KTDQKSGAQF FTLEGRHPDR SVFPDTYFSY
60 70 80 90 100
KVDEEFATPF KTVATKGLDF DPWSNNRGDD EVFDSKSRED ETKPFGLAVE
110 120 130 140 150
DRSPATTPDT TPARTPTDES TPTSEPNPFP FHEGKMFEMT RSGAIDMSKR
160 170 180 190 200
DFVEERLQFF QIGPQSPCER TDIRMAIVAD HLGLSWTELA RELNFSVDEI
210 220 230 240 250
NQIRVENPNS LISQSFMLLK KWVTRDGKNA TTDALTSVLT KINRIDIVTL
260 270 280 290 300
LEGPIFDYGN ISGTRSFADE NNVFHDPVDG WQNETSSGNL ESCAQARRVT
310 320
GGLLDRLDDS PDQCRDSITS YL
Computationally mapped potential isoform sequencesi
There are 22 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ12955 | ANK3_HUMAN | Ankyrin-3 | ANK3 | 4,377 | Annotation score: | ||
A0A087WZ65 | A0A087WZ65_HUMAN | Ankyrin-3 | ANK3 | 973 | Annotation score: | ||
H0Y3A4 | H0Y3A4_HUMAN | Ankyrin-3 | ANK3 | 459 | Annotation score: | ||
A0A087WTF3 | A0A087WTF3_HUMAN | Ankyrin-3 | ANK3 | 1,643 | Annotation score: | ||
A0A087WY90 | A0A087WY90_HUMAN | Ankyrin-3 | ANK3 | 178 | Annotation score: | ||
H0YAH5 | H0YAH5_HUMAN | Ankyrin-3 | ANK3 | 217 | Annotation score: | ||
A0A087WTE8 | A0A087WTE8_HUMAN | Ankyrin-3 | ANK3 | 241 | Annotation score: | ||
A0A087X0B4 | A0A087X0B4_HUMAN | Ankyrin-3 | ANK3 | 450 | Annotation score: | ||
H0Y951 | H0Y951_HUMAN | Ankyrin-3 | ANK3 | 166 | Annotation score: | ||
A0A087WX55 | A0A087WX55_HUMAN | Ankyrin-3 | ANK3 | 175 | Annotation score: | ||
There are more potential isoformsShow all |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 | |
Non-terminal residuei | 322 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC022390 Genomic DNA No translation available. AC023904 Genomic DNA No translation available. AL359267 Genomic DNA No translation available. AL359377 Genomic DNA No translation available. AL391707 Genomic DNA No translation available. AL592430 Genomic DNA No translation available. AL607065 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000610901; ENSP00000479337; ENSG00000151150 |
UCSCi | uc057tlp.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC022390 Genomic DNA No translation available. AC023904 Genomic DNA No translation available. AL359267 Genomic DNA No translation available. AL359377 Genomic DNA No translation available. AL391707 Genomic DNA No translation available. AL592430 Genomic DNA No translation available. AL607065 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
Proteomic databases
PeptideAtlasi | A0A087WVC2 |
Protocols and materials databases
Antibodypediai | 4197, 266 antibodies |
Genome annotation databases
Ensembli | ENST00000610901; ENSP00000479337; ENSG00000151150 |
UCSCi | uc057tlp.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000151150.20 |
HGNCi | HGNC:494, ANK3 |
OpenTargetsi | ENSG00000151150 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000154939 |
HOGENOMi | CLU_867523_0_0_1 |
Miscellaneous databases
ChiTaRSi | ANK3, human |
Gene expression databases
Bgeei | ENSG00000151150, Expressed in substantia nigra and 246 other tissues |
ExpressionAtlasi | A0A087WVC2, baseline and differential |
Family and domain databases
CDDi | cd08803, Death_ank3, 1 hit |
InterProi | View protein in InterPro IPR037971, Ank3_Death IPR011029, DEATH-like_dom_sf IPR000488, Death_domain |
Pfami | View protein in Pfam PF00531, Death, 1 hit |
SMARTi | View protein in SMART SM00005, DEATH, 1 hit |
SUPFAMi | SSF47986, SSF47986, 1 hit |
PROSITEi | View protein in PROSITE PS50017, DEATH_DOMAIN, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A087WVC2_HUMAN | |
Accessioni | A0A087WVC2Primary (citable) accession number: A0A087WVC2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 29, 2014 |
Last sequence update: | October 29, 2014 | |
Last modified: | August 12, 2020 | |
This is version 34 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |