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Protein
Submitted name:

Regulator of G-protein-signaling 3

Gene

RGS3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Regulator of G-protein-signaling 3Imported
Gene namesi
Name:RGS3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

EuPathDBiHostDB:ENSG00000138835.22
HGNCiHGNC:9999 RGS3

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000138835

PTM / Processingi

Proteomic databases

PeptideAtlasiA0A087WUY2

Expressioni

Gene expression databases

BgeeiENSG00000138835 Expressed in 228 organ(s), highest expression level in left coronary artery
ExpressionAtlasiA0A087WUY2 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A087WUY2
SMRiA0A087WUY2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini67 – 183RGSInterPro annotationAdd BLAST117

Phylogenomic databases

eggNOGiKOG3589 Eukaryota
ENOG410YMJD LUCA
GeneTreeiENSGT00760000118903

Family and domain databases

CDDicd08713 RGS_RGS3, 1 hit
Gene3Di1.10.196.10, 2 hits
InterProiView protein in InterPro
IPR016137 RGS
IPR034951 RGS_RGS3
IPR036305 RGS_sf
IPR024066 RGS_subdom1/3
PfamiView protein in Pfam
PF00615 RGS, 1 hit
PRINTSiPR01301 RGSPROTEIN
SMARTiView protein in SMART
SM00315 RGS, 1 hit
SUPFAMiSSF48097 SSF48097, 1 hit
PROSITEiView protein in PROSITE
PS50132 RGS, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

A0A087WUY2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLRGMYLTRN GNLQRRHTMK EAKDMKNKLG IFRRRNESPG APPAGKADKM
60 70 80 90 100
MKSFKPTSEE ALKWGESLEK LLVHKYGLAV FQAFLRTEFS EENLEFWLAC
110 120 130 140 150
EDFKKVKSQS KMASKAKKIF AEYIAIQACK EVNLDSYTRE HTKDNLQSVT
160 170 180 190
RGCFDLAQKR IFGLMEKDSY PRFLRSDLYL DLINQKKMSP PL
Length:192
Mass (Da):22,358
Last modified:October 29, 2014 - v1
Checksum:iB2BE37E7679D0778
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P49796RGS3_HUMAN
Regulator of G-protein signaling 3
RGS3
1,198Annotation score:
H7BXY1H7BXY1_HUMAN
Regulator of G-protein signalling 3...
RGS3 hCG_29191
168Annotation score:
Q5VXC0Q5VXC0_HUMAN
Regulator of G-protein-signaling 3
RGS3
340Annotation score:
C9J582C9J582_HUMAN
Regulator of G-protein-signaling 3
RGS3
247Annotation score:
H7C539H7C539_HUMAN
Regulator of G-protein-signaling 3
RGS3
214Annotation score:
C9J6G2C9J6G2_HUMAN
Regulator of G-protein-signaling 3
RGS3
74Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL137066 Genomic DNA No translation available.
AL162727 Genomic DNA No translation available.
AL359455 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000620489; ENSP00000479017; ENSG00000138835
UCSCiuc064vfe.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL137066 Genomic DNA No translation available.
AL162727 Genomic DNA No translation available.
AL359455 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliA0A087WUY2
SMRiA0A087WUY2
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiA0A087WUY2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000620489; ENSP00000479017; ENSG00000138835
UCSCiuc064vfe.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000138835.22
HGNCiHGNC:9999 RGS3
OpenTargetsiENSG00000138835
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3589 Eukaryota
ENOG410YMJD LUCA
GeneTreeiENSGT00760000118903

Miscellaneous databases

ChiTaRSiRGS3 human

Gene expression databases

BgeeiENSG00000138835 Expressed in 228 organ(s), highest expression level in left coronary artery
ExpressionAtlasiA0A087WUY2 baseline and differential

Family and domain databases

CDDicd08713 RGS_RGS3, 1 hit
Gene3Di1.10.196.10, 2 hits
InterProiView protein in InterPro
IPR016137 RGS
IPR034951 RGS_RGS3
IPR036305 RGS_sf
IPR024066 RGS_subdom1/3
PfamiView protein in Pfam
PF00615 RGS, 1 hit
PRINTSiPR01301 RGSPROTEIN
SMARTiView protein in SMART
SM00315 RGS, 1 hit
SUPFAMiSSF48097 SSF48097, 1 hit
PROSITEiView protein in PROSITE
PS50132 RGS, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A087WUY2_HUMAN
AccessioniPrimary (citable) accession number: A0A087WUY2
Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: September 12, 2018
This is version 29 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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