UniProtKB - A0A087WQ31 (A0A087WQ31_MOUSE)
Protein
Submitted name:
CLIP-associating protein 1
Gene
Clasp1
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- kinetochore binding Source: InterPro
- microtubule plus-end binding Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: CLIP-associating protein 1Imported |
Gene namesi | Name:Clasp1Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1923957, Clasp1 |
Subcellular locationi
Cytoskeleton
- centrosome ARBA annotation
Golgi apparatus
- trans-Golgi network ARBA annotation
Other locations
- kinetochore ARBA annotation
Cytoskeleton
- cytoplasmic microtubule Source: InterPro
- kinetochore microtubule Source: InterPro
- microtubule organizing center Source: UniProtKB-SubCell
Golgi apparatus
- Golgi apparatus Source: UniProtKB-SubCell
Other locations
- condensed chromosome kinetochore Source: UniProtKB-SubCell
Keywords - Cellular componenti
CentromereARBA annotation, ChromosomeARBA annotation, CytoplasmARBA annotation, KinetochoreARBA annotationExpressioni
Gene expression databases
Bgeei | ENSMUSG00000064302, Expressed in heart and 289 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 232 | TOGInterPro annotationAdd BLAST | 232 | |
Repeati | 168 – 206 | HEATPROSITE-ProRule annotationAdd BLAST | 39 | |
Domaini | 319 – 551 | TOGInterPro annotationAdd BLAST | 233 | |
Domaini | 863 – 1101 | TOGInterPro annotationAdd BLAST | 239 | |
Domaini | 1303 – 1541 | TOGInterPro annotationAdd BLAST | 239 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 237 – 290 | DisorderedSequence analysisAdd BLAST | 54 | |
Regioni | 543 – 600 | DisorderedSequence analysisAdd BLAST | 58 | |
Regioni | 612 – 792 | DisorderedSequence analysisAdd BLAST | 181 | |
Regioni | 1095 – 1174 | DisorderedSequence analysisAdd BLAST | 80 | |
Regioni | 1217 – 1250 | DisorderedSequence analysisAdd BLAST | 34 | |
Regioni | 1262 – 1283 | DisorderedSequence analysisAdd BLAST | 22 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 1322 – 1342 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 1404 – 1424 | Sequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 250 – 288 | PolarSequence analysisAdd BLAST | 39 | |
Compositional biasi | 651 – 700 | PolarSequence analysisAdd BLAST | 50 | |
Compositional biasi | 713 – 761 | PolarSequence analysisAdd BLAST | 49 | |
Compositional biasi | 1095 – 1136 | PolarSequence analysisAdd BLAST | 42 |
Keywords - Domaini
Coiled coilSequence analysis, RepeatARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000154817 |
OrthoDBi | 66632at2759 |
Family and domain databases
Gene3Di | 1.25.10.10, 4 hits |
InterProi | View protein in InterPro IPR011989, ARM-like IPR016024, ARM-type_fold IPR028399, CLASP_1 IPR024395, CLASP_N_dom IPR021133, HEAT_type_2 IPR034085, TOG |
PANTHERi | PTHR21567:SF28, PTHR21567:SF28, 1 hit |
Pfami | View protein in Pfam PF12348, CLASP_N, 2 hits |
SMARTi | View protein in SMART SM01349, TOG, 4 hits |
SUPFAMi | SSF48371, SSF48371, 2 hits |
PROSITEi | View protein in PROSITE PS50077, HEAT_REPEAT, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 17 potential isoforms that are computationally mapped.Show allAlign All
A0A087WQ31-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEPRMESCLA QVLQKDVGKR LQVGQELIDY FSDRQKSADL EHDQTLLDKL
60 70 80 90 100
VDGLATSWVN SSNYKVVLLG MDILSALVTR LQDRFKAQIG TVLPSLIDRL
110 120 130 140 150
GDAKDSVREQ DQTLLLKIMD QAANPQYVWD RMLGGFKHKN FRTREGICLC
160 170 180 190 200
LIATLNASGA QTLTLSKIVP HICNLLGDPN SQVRDAAINS LVEIYRHVGE
210 220 230 240 250
RVRADLSKKG LPQSRLNVIF TKFDEVQKSG NMIQSANEKN FDDEDSVDGN
260 270 280 290 300
RPSSASSSSS KAPSSSRRNV NLGTTRRLMS SSLGSKSSAA KEGAGAVDEE
310 320 330 340 350
DFIKAFDDVP VVQIYSSRDL EESINKIREI LSDDKHDWEQ RVNALKKIRS
360 370 380 390 400
LLLAGAAEYD NFFQHLRLLD GAFKLSAKDL RSQVVREACI TLGHLSSVLG
410 420 430 440 450
NKFDHGAEAI MPTIFNLIPN SAKIMATSGV VAVRLIIRHT HIPRLIPVIT
460 470 480 490 500
SNCTSKSVAV RRRCFEFLDL LLQEWQTHSL ERHISVLAET IKKGIHDADS
510 520 530 540 550
EARIEARKCY WGFHSHFSRE AEHLYHTLES SYQKALQSHL KNSDSIVSLP
560 570 580 590 600
QSDRSSSSSQ ESLNRPLSAK RSPTGSTASR GSTVSTKSVS TTGSLQRSRS
610 620 630 640 650
DIDVNAAASA KSKVSSSSGS PAFSSAAALP PGSYASLDGT TTKAEGRIRT
660 670 680 690 700
RRQSSGSTTN VASTPSDSRG RSRAKVVSQS QRSRSANPAG AGSRSSSPGK
710 720 730 740 750
LLGSGLAGGS SRGPPVTPSS EKRSKIPRSQ GCSRETSPNR IGLARSSRIP
760 770 780 790 800
RPSMSQGCSR DTSRESSRDT SPARGFTPLD RFGLGQSGRI PGSVNAMRVL
810 820 830 840 850
STSTDLEAAV ADALLLGDAR SKKKPVRRRY EPYGMYSDDD ANSDASSVCS
860 870 880 890 900
ERSYGSRNGG IPHYLRQTED VAEVLNHCAS SNWSERKEGL LGLQNLLKSQ
910 920 930 940 950
RTLSRVELKR LCEIFTRMFA DPHSKRVFSM FLETLVDFII IHKDDLQDWL
960 970 980 990 1000
FVLLTQLLKK MGADLLGSVQ AKVQKALDVT RDSFPFDQQF NILMRFIVDQ
1010 1020 1030 1040 1050
TQTPNLKVKV AILKYIESLA RQMDPTDFVN SSETRLAVSR IITWTTEPKS
1060 1070 1080 1090 1100
SDVRKAAQIV LISLFELNTP EFTMLLGALP KTFQDGATKL LHNHLKNSSN
1110 1120 1130 1140 1150
TGVGSPSNTI GRTPSRHPSS RTSPLTSPTN CSHGGLSPSR LWGWSADGLS
1160 1170 1180 1190 1200
KPPPPFSQPN SIPTAPSHKT LRRSYSPSML DYDTENLNSE EIYSSLRGVT
1210 1220 1230 1240 1250
EAIEKFSFRS QEDLNEPIKR DGKKDCDIVS RDGGAASPAT EGRGGSEIEG
1260 1270 1280 1290 1300
GRMALDNKTS LLNTQPPRAF PGPRAREYNP YPYSDTINTY DKTALKEAVF
1310 1320 1330 1340 1350
DDDMEQLRDV PIDHSDLVAD LLKELSNHNE RVEERKGALL ELLKITREDS
1360 1370 1380 1390 1400
LGVWEEHFKT ILLLLLETLG DKDHSIRALA LRVLREILRN QPARFKNYAE
1410 1420 1430 1440 1450
LTIMKTLEAH KDSHKEVVRA AEEAASTLAS SIHPEQCIKV LCPIIQTADY
1460 1470 1480 1490 1500
PINLAAIKMQ TKVVERITKE SLLQLLVDII PGLLQGYDNT ESSVRKASVF
1510 1520 1530 1540 1550
CLVAIYSVIG EDLKPHLAQL TGSKMKLLNL YIKRAQTTNS NSSSSSDVST
HS
Computationally mapped potential isoform sequencesi
There are 17 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ80TV8 | CLAP1_MOUSE | CLIP-associating protein 1 | Clasp1 Kiaa0622 | 1,535 | Annotation score: | ||
A0A087WQF1 | A0A087WQF1_MOUSE | CLIP-associating protein 1 | Clasp1 | 1,468 | Annotation score: | ||
E9Q6L0 | E9Q6L0_MOUSE | CLIP-associating protein 1 | Clasp1 | 1,452 | Annotation score: | ||
A0A087WS18 | A0A087WS18_MOUSE | CLIP-associating protein 1 | Clasp1 | 1,460 | Annotation score: | ||
E9QKH0 | E9QKH0_MOUSE | CLIP-associating protein 1 | Clasp1 | 1,536 | Annotation score: | ||
A0A087WRE8 | A0A087WRE8_MOUSE | CLIP-associating protein 1 | Clasp1 | 1,526 | Annotation score: | ||
A0A087WRK0 | A0A087WRK0_MOUSE | CLIP-associating protein 1 | Clasp1 | 1,477 | Annotation score: | ||
E9QNY9 | E9QNY9_MOUSE | CLIP-associating protein 1 | Clasp1 | 1,526 | Annotation score: | ||
J3QP81 | J3QP81_MOUSE | CLIP-associating protein 1 | Clasp1 | 1,459 | Annotation score: | ||
A0A087WQ95 | A0A087WQ95_MOUSE | CLIP-associating protein 1 | Clasp1 | 1,469 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC109294 Genomic DNA No translation available. AC131804 Genomic DNA No translation available. AC136636 Genomic DNA No translation available. |
RefSeqi | NP_001280229.1, NM_001293300.1 |
Genome annotation databases
Ensembli | ENSMUST00000190571; ENSMUSP00000140019; ENSMUSG00000064302 |
GeneIDi | 76707 |
KEGGi | mmu:76707 |
UCSCi | uc011wqm.2, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC109294 Genomic DNA No translation available. AC131804 Genomic DNA No translation available. AC136636 Genomic DNA No translation available. |
RefSeqi | NP_001280229.1, NM_001293300.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
jPOSTi | A0A087WQ31 |
Protocols and materials databases
Antibodypediai | 33401, 275 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000190571; ENSMUSP00000140019; ENSMUSG00000064302 |
GeneIDi | 76707 |
KEGGi | mmu:76707 |
UCSCi | uc011wqm.2, mouse |
Organism-specific databases
CTDi | 23332 |
MGIi | MGI:1923957, Clasp1 |
Phylogenomic databases
GeneTreei | ENSGT00940000154817 |
OrthoDBi | 66632at2759 |
Miscellaneous databases
BioGRID-ORCSi | 76707, 0 hits in 8 CRISPR screens |
ChiTaRSi | Clasp1, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000064302, Expressed in heart and 289 other tissues |
Family and domain databases
Gene3Di | 1.25.10.10, 4 hits |
InterProi | View protein in InterPro IPR011989, ARM-like IPR016024, ARM-type_fold IPR028399, CLASP_1 IPR024395, CLASP_N_dom IPR021133, HEAT_type_2 IPR034085, TOG |
PANTHERi | PTHR21567:SF28, PTHR21567:SF28, 1 hit |
Pfami | View protein in Pfam PF12348, CLASP_N, 2 hits |
SMARTi | View protein in SMART SM01349, TOG, 4 hits |
SUPFAMi | SSF48371, SSF48371, 2 hits |
PROSITEi | View protein in PROSITE PS50077, HEAT_REPEAT, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A087WQ31_MOUSE | |
Accessioni | A0A087WQ31Primary (citable) accession number: A0A087WQ31 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 29, 2014 |
Last sequence update: | October 29, 2014 | |
Last modified: | December 2, 2020 | |
This is version 49 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |