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UniProtKB - A0A087WPR7 (A0A087WPR7_MOUSE)

Entry version 45 (19 Jan 2022)
Sequence version 1 (29 Oct 2014)
Previous versions | rss
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Protein
Submitted name:

Dystonin

Gene

Dst

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
DystoninImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DstImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:104627, Dst

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSMUSG00000026131

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, CytoskeletonARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

PhosphoproteinARBA annotation

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		A0A087WPR7

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		348986

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000026131, Expressed in skin of back and 301 other tissues

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		A0A087WPR7

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini561 – 618SH3InterPro annotationAdd BLAST58

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 24DisorderedSequence analysisAdd BLAST24
Regioni1789 – 1875DisorderedSequence analysisAdd BLAST87
Regioni1890 – 1928DisorderedSequence analysisAdd BLAST39
Regioni1949 – 2100DisorderedSequence analysisAdd BLAST152
Regioni2148 – 2495DisorderedSequence analysisAdd BLAST348
Regioni2719 – 2738DisorderedSequence analysisAdd BLAST20
Regioni2956 – 2987DisorderedSequence analysisAdd BLAST32

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili133 – 153Sequence analysisAdd BLAST21
Coiled coili351 – 371Sequence analysisAdd BLAST21
Coiled coili415 – 442Sequence analysisAdd BLAST28
Coiled coili514 – 534Sequence analysisAdd BLAST21
Coiled coili783 – 803Sequence analysisAdd BLAST21
Coiled coili882 – 916Sequence analysisAdd BLAST35
Coiled coili1092 – 1122Sequence analysisAdd BLAST31

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1789 – 1817Polar residuesSequence analysisAdd BLAST29
Compositional biasi1856 – 1870Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi1956 – 1983Polar residuesSequence analysisAdd BLAST28
Compositional biasi1996 – 2018Polar residuesSequence analysisAdd BLAST23
Compositional biasi2059 – 2100Basic and acidic residuesSequence analysisAdd BLAST42
Compositional biasi2154 – 2174Polar residuesSequence analysisAdd BLAST21
Compositional biasi2180 – 2214Basic and acidic residuesSequence analysisAdd BLAST35
Compositional biasi2215 – 2233Polar residuesSequence analysisAdd BLAST19
Compositional biasi2235 – 2251Basic and acidic residuesSequence analysisAdd BLAST17
Compositional biasi2295 – 2311Polar residuesSequence analysisAdd BLAST17
Compositional biasi2352 – 2368Polar residuesSequence analysisAdd BLAST17
Compositional biasi2438 – 2455Basic and acidic residuesSequence analysisAdd BLAST18
Compositional biasi2466 – 2480Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi2724 – 2738Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi2970 – 2987Basic and acidic residuesSequence analysisAdd BLAST18

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the plakin or cytolinker family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysis, RepeatARBA annotation, SH3 domainPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00940000155008

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_000015_3_0_1

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.90.1290.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR041615, Desmoplakin_SH3
IPR041573, Desmoplakin_Spectrin-like
IPR043197, Plakin
IPR035915, Plakin_repeat_sf
IPR001101, Plectin_repeat
IPR001452, SH3_domain
IPR018159, Spectrin/alpha-actinin
IPR002017, Spectrin_repeat

The PANTHER Classification System

More...PANTHERi		PTHR23169, PTHR23169, 3 hits

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00681, Plectin, 1 hit
PF17902, SH3_10, 1 hit
PF00435, Spectrin, 1 hit
PF18373, Spectrin_like, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00250, PLEC, 9 hits
SM00150, SPEC, 4 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF75399, SSF75399, 2 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50002, SH3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

This entry has 1 described isoform and 13 potential isoforms that are computationally mapped.Show allAlign All

A0A087WPR7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQSSSYSYRS SDSVFSNTTS TRTSLDSNEN LLSVHCGPTL INSCISFSNE 
        60         70         80         90        100
SLDGHRLDML QQIATRVQRD SVSCEDKLIL ARNALQSDSK RLESGVQFQN 
       110        120        130        140        150
EAEIAGYILE CENLLRQHVI DVQILIDGKY YQADQLVQRV AKLRDEIMAL 
       160        170        180        190        200
RNECSSVYSK GRMLTTEQTK LMISGITQSL NSGFAQTLHP SLNSGLTQSL 
       210        220        230        240        250
TPSLTSSSVT SGLSSGMTSR LTPSVTPVYA PGFPSVVAPN FSLGVEPNSL 
       260        270        280        290        300
QTLKLMQIRK PLLKSSLLDQ NLTEEEVNMK FVQDLLNWVD EMQVQLDRTE 
       310        320        330        340        350
WGSDLPSVES HLENHKNVHR AIEEFESSLK EAKISEIQMT APLKLSYTDK 
       360        370        380        390        400
LHRLESQYAK LLNTSRNQER HLDTLHNFVT RATNELIWLN EKEESEVAYD 
       410        420        430        440        450
WSERNSSVAR KKSYHAELMR ELEQKEESIK AVQEIAEQLL LENHPARLTI 
       460        470        480        490        500
EAYRAAMQTQ WSWILQLCQC VEQHIQENSA YFEFFNDAKE ATDYLRNLKD 
       510        520        530        540        550
AIQRKYSCDR SSSIHKLEDL VQESMEEKEE LLQYRSVVAG LMGRAKTVVQ 
       560        570        580        590        600
LKPRNPDNPL KTSIPIKAIC DYRQIEITIY KDDECVLANN SHRAKWKVIS 
       610        620        630        640        650
PTGNEAMVPS VCFTVPPPNK EAVDFANRIE QQYQSVLTLW HESHINMKSV 
       660        670        680        690        700
VSWHYLVNEI DRIRASNVAS IKTMLPGEHQ QVLSNLQSRL EDFLEDSQES 
       710        720        730        740        750
QIFSGSDISQ LEKEVSVCRK YYQELLKSAE REEQEESVYN LYISEVRNIR 
       760        770        780        790        800
LRLESCEDRL IRQIRTPLER DDLHESMLRI TEQEKLKKEL DRLKDDLGTI 
       810        820        830        840        850
TNKCEEFFSQ AADSPSVPAL RSELSVVIQS LSQIYSMSST YIEKLKTVNL 
       860        870        880        890        900
VLKNTQAAEA LVKLYETKLC EEEAVIADKN NIENLMSTLK QWRSEVDEKR 
       910        920        930        940        950
EVFHALEDEL QKAKAISDEM FKTHKERDLD FDWHKEKADQ LVERWQSVHV 
       960        970        980        990       1000
QIDNRLRDLE GIGKSLKHYR DSYHPLDDWI QHIETTQRKI QENQPENSKA 
      1010       1020       1030       1040       1050
LALQLNQQKM LVSEIEVKQS KMDECQKYSE QYSAAVKDYE LQTMTYRAMV 
      1060       1070       1080       1090       1100
ESQQKSPVKR RRIQSSADLV IQEFMDLRTR YTALVTLMTQ YIKFAGDSLK 
      1110       1120       1130       1140       1150
RLEEEEKSLD EEKKQHIEKA KELQKWVSNI SKTLGDGEKA GKPLFSKQQM 
      1160       1170       1180       1190       1200
SSKEISTKKE QFSEALQTTQ IFLAKHGDKL TEEERSDLEK QVKTLQEGYN 
      1210       1220       1230       1240       1250
LLFSESLKQQ ELQPSGESKV PEKPDKVIAG TINQTTGEVL SVFQAVLRGL 
      1260       1270       1280       1290       1300
IDYETGIRLL EAQLVITGLI SPELRKCFDL RDAESHGLID EQVLRQLKEL 
      1310       1320       1330       1340       1350
NRAKQLISTA SPTSIPVLDS LAQGMVSESM AIRVLEILLS AGPLLVPATG 
      1360       1370       1380       1390       1400
EHLTLQQAFQ QNLISSALFS KVLERQDTCK DLIDPCTSEK VSLTDMVQRS 
      1410       1420       1430       1440       1450
ILQENTRMWL LPVRPQEAGR ITLKCGRSVS ILRAAHEGLI DRETMFRLLG 
      1460       1470       1480       1490       1500
AQLLSGGLID CNSGQKMTVE EAVAEGVIDR DTASSILTYQ VQTGGIVHSN 
      1510       1520       1530       1540       1550
PAKRLTVDEA VQCELITSSS ALLVLEAQRG YVGLIWPHSG EIFPTSSSLQ 
      1560       1570       1580       1590       1600
QELITNELAS KILNGRQKIA ALYIPESSQV IGLDAAKQLG IIDNNTASVL 
      1610       1620       1630       1640       1650
KSVTLPDKMP DLGDLEDCKN AKRWLSFCKL QPSTVHDYRQ EEGGSDGEEP 
      1660       1670       1680       1690       1700
VTAQSSEQTK KLFLSYLMVN SYMDAHTGQR LLLYDGDLDE AVGMLLESCG 
      1710       1720       1730       1740       1750
TELGADTSTR ESLSVLTIPD AFPDCALSEE KHECSAAAAG PDKCHYSHPG 
      1760       1770       1780       1790       1800
HKESLENAKW DMNEAFCKMG NNDSNGELPR PENLADTTVV QKGSESPSRV 
      1810       1820       1830       1840       1850
RVPKPTSSST QPEGSVLRPE SGSILKGCKS QSEPVTKKYP DGANHSHFLT 
      1860       1870       1880       1890       1900
SETSRPCDSN EREDEENIQK GPSVFDYSPR LSALLSHDEL RQSQGRFSDT 
      1910       1920       1930       1940       1950
STPQNTGYLC EASTLSPSDQ RVLADQSTRE KFQDQFLGIA AISVSLQGAP 
      1960       1970       1980       1990       2000
CGQKPVDTEC SSSQVHYHSE ESMSDASAES GATRQTDESE KTGSKVEDNS 
      2010       2020       2030       2040       2050
CTMVPGGGSR NDNTSDCGPL SHKGAIDAGD YETSLLAGQQ SDTATDSDSD 
      2060       2070       2080       2090       2100
DYFYDTPLFE DEDHDSLILQ GDDRDCLQPE DYDTSLQEEN DRTPPPDDIF 
      2110       2120       2130       2140       2150
YDVMKEKENP EFPHGGMDES LGVENKVCCP QGFPVGIEKP ELYLAGEKEF 
      2160       2170       2180       2190       2200
NSGGSEQLVE SVSESENPPG LWDSESDSLT EGEIIGRKER LGASLTPDGH 
      2210       2220       2230       2240       2250
WRGDREECDT SRESQSDTDG VGSIQSSESY RPYMSDGSDL DEEDNGGRSS 
      2260       2270       2280       2290       2300
EDSGDGRGGQ GVADEGGEPQ YQADPTQLYT AIRKEHGGET QNVSDMIPLD 
      2310       2320       2330       2340       2350
KTHSYSPLET QHGAGVFQPE SAGRGGWDTE RSSHPELTTE ADEEDEASLS 
      2360       2370       2380       2390       2400
THMATKGVSL SNAEGTASEE IRLVQGPDST GILKAEDLEN VSPEISPSSD 
      2410       2420       2430       2440       2450
NIVRSEAELG GGASEDGHLS FTGSDRDQQG PGRGLVKGRD GQSDKLVDET 
      2460       2470       2480       2490       2500
SIREMGFQKE GVLMSSPEEG GEEERDLEPF PNGSATESLN MGKSQVPPLL 
      2510       2520       2530       2540       2550
THTEELSHRG APHTTTMTTT MTLEGEAKNV QTGLTESPVL LETLAEIFDT 
      2560       2570       2580       2590       2600
PASKVTRADL TSAVTASEMK SQVKEDSLTG GPEKETGPCT SLGHCDKCIH 
      2610       2620       2630       2640       2650
VDMLEPNEHT PSCALVAPPT VKDNLCSVNN AGEKSVRPQE DWPPAAEVRL 
      2660       2670       2680       2690       2700
SDACVEESIS EGKAGILQFT PENSDSTLSR LPHQSVAGWG KSADSVQARL 
      2710       2720       2730       2740       2750
PVSGVRHTSA DTLDVGCPQL ESSREKASAE EEPHRERALS LKPQEREHHM 
      2760       2770       2780       2790       2800
LGFVEDGRSI LKSSLDKVHM NLQEVGDPSA GTGTKISIQN LIRRAILSEL 
      2810       2820       2830       2840       2850
PNEVSNVPSH GISPISNSSE VRAESGGDPF CITSFLHLLK QNQPPQETPG 
      2860       2870       2880       2890       2900
ISELAKVLTQ MDCDPEQRGL GSELLPPQLK NAFYKLLFDG YATEKDQAEA 
      2910       2920       2930       2940       2950
LGQTSCAVPK MAEEKPHVCS DLRNKEGHHC PLNPQAVGEA EVEPFSVHIA 
      2960       2970       2980 
ALPGGEKLGE LCSEPPEHSE STSGSKERSS DSSSKEK
Length:2,987
Mass (Da):331,491
Last modified:October 29, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1944918A507D9BB2
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 13 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q91ZU6DYST_MOUSE
Dystonin
Dst Bpag1, Macf2
7,393Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R1P5S4R1P5_MOUSE
Dystonin
Dst
7,717Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9Q9X1E9Q9X1_MOUSE
Dystonin
Dst
7,406Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WSP0A0A087WSP0_MOUSE
Dystonin
Dst
5,175Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R1Y6S4R1Y6_MOUSE
Dystonin
Dst
1,638Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WRB8A0A087WRB8_MOUSE
Dystonin
Dst
1,471Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R2A8S4R2A8_MOUSE
Dystonin
Dst
262Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R2C6S4R2C6_MOUSE
Dystonin
Dst
259Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1D5RLZ3A0A1D5RLZ3_MOUSE
Dystonin
Dst
1,674Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0A6YXR1A0A0A6YXR1_MOUSE
Dystonin
Dst
282Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei2987Imported1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000185897; ENSMUSP00000139888; ENSMUSG00000026131

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

SMRiA0A087WPR7
ModBaseiSearch...

Proteomic databases

jPOSTiA0A087WPR7
ProteomicsDBi348986

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		31066, 184 antibodies from 22 providers

Genome annotation databases

EnsembliENSMUST00000185897; ENSMUSP00000139888; ENSMUSG00000026131

Organism-specific databases

MGIiMGI:104627, Dst
VEuPathDBiHostDB:ENSMUSG00000026131

Phylogenomic databases

GeneTreeiENSGT00940000155008
HOGENOMiCLU_000015_3_0_1

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Dst, mouse

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000026131, Expressed in skin of back and 301 other tissues

Family and domain databases

Gene3Di3.90.1290.10, 2 hits
InterProiView protein in InterPro
IPR041615, Desmoplakin_SH3
IPR041573, Desmoplakin_Spectrin-like
IPR043197, Plakin
IPR035915, Plakin_repeat_sf
IPR001101, Plectin_repeat
IPR001452, SH3_domain
IPR018159, Spectrin/alpha-actinin
IPR002017, Spectrin_repeat
PANTHERiPTHR23169, PTHR23169, 3 hits
PfamiView protein in Pfam
PF00681, Plectin, 1 hit
PF17902, SH3_10, 1 hit
PF00435, Spectrin, 1 hit
PF18373, Spectrin_like, 1 hit
SMARTiView protein in SMART
SM00250, PLEC, 9 hits
SM00150, SPEC, 4 hits
SUPFAMiSSF75399, SSF75399, 2 hits
PROSITEiView protein in PROSITE
PS50002, SH3, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A087WPR7_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A087WPR7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: January 19, 2022
This is version 45 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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