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Entry version 45 (19 Jan 2022)
Sequence version 1 (29 Oct 2014)
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Protein
Submitted name:

Dystonin

Gene

Dst

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
DystoninImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DstImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:104627, Dst

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSMUSG00000026131

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, CytoskeletonARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

PhosphoproteinARBA annotation

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
A0A087WPR7

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
348986

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000026131, Expressed in skin of back and 301 other tissues

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A0A087WPR7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini561 – 618SH3InterPro annotationAdd BLAST58

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 24DisorderedSequence analysisAdd BLAST24
Regioni1789 – 1875DisorderedSequence analysisAdd BLAST87
Regioni1890 – 1928DisorderedSequence analysisAdd BLAST39
Regioni1949 – 2100DisorderedSequence analysisAdd BLAST152
Regioni2148 – 2495DisorderedSequence analysisAdd BLAST348
Regioni2719 – 2738DisorderedSequence analysisAdd BLAST20
Regioni2956 – 2987DisorderedSequence analysisAdd BLAST32

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili133 – 153Sequence analysisAdd BLAST21
Coiled coili351 – 371Sequence analysisAdd BLAST21
Coiled coili415 – 442Sequence analysisAdd BLAST28
Coiled coili514 – 534Sequence analysisAdd BLAST21
Coiled coili783 – 803Sequence analysisAdd BLAST21
Coiled coili882 – 916Sequence analysisAdd BLAST35
Coiled coili1092 – 1122Sequence analysisAdd BLAST31

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1789 – 1817Polar residuesSequence analysisAdd BLAST29
Compositional biasi1856 – 1870Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi1956 – 1983Polar residuesSequence analysisAdd BLAST28
Compositional biasi1996 – 2018Polar residuesSequence analysisAdd BLAST23
Compositional biasi2059 – 2100Basic and acidic residuesSequence analysisAdd BLAST42
Compositional biasi2154 – 2174Polar residuesSequence analysisAdd BLAST21
Compositional biasi2180 – 2214Basic and acidic residuesSequence analysisAdd BLAST35
Compositional biasi2215 – 2233Polar residuesSequence analysisAdd BLAST19
Compositional biasi2235 – 2251Basic and acidic residuesSequence analysisAdd BLAST17
Compositional biasi2295 – 2311Polar residuesSequence analysisAdd BLAST17
Compositional biasi2352 – 2368Polar residuesSequence analysisAdd BLAST17
Compositional biasi2438 – 2455Basic and acidic residuesSequence analysisAdd BLAST18
Compositional biasi2466 – 2480Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi2724 – 2738Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi2970 – 2987Basic and acidic residuesSequence analysisAdd BLAST18

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the plakin or cytolinker family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysis, RepeatARBA annotation, SH3 domainPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155008

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000015_3_0_1

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.90.1290.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR041615, Desmoplakin_SH3
IPR041573, Desmoplakin_Spectrin-like
IPR043197, Plakin
IPR035915, Plakin_repeat_sf
IPR001101, Plectin_repeat
IPR001452, SH3_domain
IPR018159, Spectrin/alpha-actinin
IPR002017, Spectrin_repeat

The PANTHER Classification System

More...
PANTHERi
PTHR23169, PTHR23169, 3 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00681, Plectin, 1 hit
PF17902, SH3_10, 1 hit
PF00435, Spectrin, 1 hit
PF18373, Spectrin_like, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00250, PLEC, 9 hits
SM00150, SPEC, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF75399, SSF75399, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50002, SH3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

This entry has 1 described isoform and 13 potential isoforms that are computationally mapped.Show allAlign All

A0A087WPR7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQSSSYSYRS SDSVFSNTTS TRTSLDSNEN LLSVHCGPTL INSCISFSNE
60 70 80 90 100
SLDGHRLDML QQIATRVQRD SVSCEDKLIL ARNALQSDSK RLESGVQFQN
110 120 130 140 150
EAEIAGYILE CENLLRQHVI DVQILIDGKY YQADQLVQRV AKLRDEIMAL
160 170 180 190 200
RNECSSVYSK GRMLTTEQTK LMISGITQSL NSGFAQTLHP SLNSGLTQSL
210 220 230 240 250
TPSLTSSSVT SGLSSGMTSR LTPSVTPVYA PGFPSVVAPN FSLGVEPNSL
260 270 280 290 300
QTLKLMQIRK PLLKSSLLDQ NLTEEEVNMK FVQDLLNWVD EMQVQLDRTE
310 320 330 340 350
WGSDLPSVES HLENHKNVHR AIEEFESSLK EAKISEIQMT APLKLSYTDK
360 370 380 390 400
LHRLESQYAK LLNTSRNQER HLDTLHNFVT RATNELIWLN EKEESEVAYD
410 420 430 440 450
WSERNSSVAR KKSYHAELMR ELEQKEESIK AVQEIAEQLL LENHPARLTI
460 470 480 490 500
EAYRAAMQTQ WSWILQLCQC VEQHIQENSA YFEFFNDAKE ATDYLRNLKD
510 520 530 540 550
AIQRKYSCDR SSSIHKLEDL VQESMEEKEE LLQYRSVVAG LMGRAKTVVQ
560 570 580 590 600
LKPRNPDNPL KTSIPIKAIC DYRQIEITIY KDDECVLANN SHRAKWKVIS
610 620 630 640 650
PTGNEAMVPS VCFTVPPPNK EAVDFANRIE QQYQSVLTLW HESHINMKSV
660 670 680 690 700
VSWHYLVNEI DRIRASNVAS IKTMLPGEHQ QVLSNLQSRL EDFLEDSQES
710 720 730 740 750
QIFSGSDISQ LEKEVSVCRK YYQELLKSAE REEQEESVYN LYISEVRNIR
760 770 780 790 800
LRLESCEDRL IRQIRTPLER DDLHESMLRI TEQEKLKKEL DRLKDDLGTI
810 820 830 840 850
TNKCEEFFSQ AADSPSVPAL RSELSVVIQS LSQIYSMSST YIEKLKTVNL
860 870 880 890 900
VLKNTQAAEA LVKLYETKLC EEEAVIADKN NIENLMSTLK QWRSEVDEKR
910 920 930 940 950
EVFHALEDEL QKAKAISDEM FKTHKERDLD FDWHKEKADQ LVERWQSVHV
960 970 980 990 1000
QIDNRLRDLE GIGKSLKHYR DSYHPLDDWI QHIETTQRKI QENQPENSKA
1010 1020 1030 1040 1050
LALQLNQQKM LVSEIEVKQS KMDECQKYSE QYSAAVKDYE LQTMTYRAMV
1060 1070 1080 1090 1100
ESQQKSPVKR RRIQSSADLV IQEFMDLRTR YTALVTLMTQ YIKFAGDSLK
1110 1120 1130 1140 1150
RLEEEEKSLD EEKKQHIEKA KELQKWVSNI SKTLGDGEKA GKPLFSKQQM
1160 1170 1180 1190 1200
SSKEISTKKE QFSEALQTTQ IFLAKHGDKL TEEERSDLEK QVKTLQEGYN
1210 1220 1230 1240 1250
LLFSESLKQQ ELQPSGESKV PEKPDKVIAG TINQTTGEVL SVFQAVLRGL
1260 1270 1280 1290 1300
IDYETGIRLL EAQLVITGLI SPELRKCFDL RDAESHGLID EQVLRQLKEL
1310 1320 1330 1340 1350
NRAKQLISTA SPTSIPVLDS LAQGMVSESM AIRVLEILLS AGPLLVPATG
1360 1370 1380 1390 1400
EHLTLQQAFQ QNLISSALFS KVLERQDTCK DLIDPCTSEK VSLTDMVQRS
1410 1420 1430 1440 1450
ILQENTRMWL LPVRPQEAGR ITLKCGRSVS ILRAAHEGLI DRETMFRLLG
1460 1470 1480 1490 1500
AQLLSGGLID CNSGQKMTVE EAVAEGVIDR DTASSILTYQ VQTGGIVHSN
1510 1520 1530 1540 1550
PAKRLTVDEA VQCELITSSS ALLVLEAQRG YVGLIWPHSG EIFPTSSSLQ
1560 1570 1580 1590 1600
QELITNELAS KILNGRQKIA ALYIPESSQV IGLDAAKQLG IIDNNTASVL
1610 1620 1630 1640 1650
KSVTLPDKMP DLGDLEDCKN AKRWLSFCKL QPSTVHDYRQ EEGGSDGEEP
1660 1670 1680 1690 1700
VTAQSSEQTK KLFLSYLMVN SYMDAHTGQR LLLYDGDLDE AVGMLLESCG
1710 1720 1730 1740 1750
TELGADTSTR ESLSVLTIPD AFPDCALSEE KHECSAAAAG PDKCHYSHPG
1760 1770 1780 1790 1800
HKESLENAKW DMNEAFCKMG NNDSNGELPR PENLADTTVV QKGSESPSRV
1810 1820 1830 1840 1850
RVPKPTSSST QPEGSVLRPE SGSILKGCKS QSEPVTKKYP DGANHSHFLT
1860 1870 1880 1890 1900
SETSRPCDSN EREDEENIQK GPSVFDYSPR LSALLSHDEL RQSQGRFSDT
1910 1920 1930 1940 1950
STPQNTGYLC EASTLSPSDQ RVLADQSTRE KFQDQFLGIA AISVSLQGAP
1960 1970 1980 1990 2000
CGQKPVDTEC SSSQVHYHSE ESMSDASAES GATRQTDESE KTGSKVEDNS
2010 2020 2030 2040 2050
CTMVPGGGSR NDNTSDCGPL SHKGAIDAGD YETSLLAGQQ SDTATDSDSD
2060 2070 2080 2090 2100
DYFYDTPLFE DEDHDSLILQ GDDRDCLQPE DYDTSLQEEN DRTPPPDDIF
2110 2120 2130 2140 2150
YDVMKEKENP EFPHGGMDES LGVENKVCCP QGFPVGIEKP ELYLAGEKEF
2160 2170 2180 2190 2200
NSGGSEQLVE SVSESENPPG LWDSESDSLT EGEIIGRKER LGASLTPDGH
2210 2220 2230 2240 2250
WRGDREECDT SRESQSDTDG VGSIQSSESY RPYMSDGSDL DEEDNGGRSS
2260 2270 2280 2290 2300
EDSGDGRGGQ GVADEGGEPQ YQADPTQLYT AIRKEHGGET QNVSDMIPLD
2310 2320 2330 2340 2350
KTHSYSPLET QHGAGVFQPE SAGRGGWDTE RSSHPELTTE ADEEDEASLS
2360 2370 2380 2390 2400
THMATKGVSL SNAEGTASEE IRLVQGPDST GILKAEDLEN VSPEISPSSD
2410 2420 2430 2440 2450
NIVRSEAELG GGASEDGHLS FTGSDRDQQG PGRGLVKGRD GQSDKLVDET
2460 2470 2480 2490 2500
SIREMGFQKE GVLMSSPEEG GEEERDLEPF PNGSATESLN MGKSQVPPLL
2510 2520 2530 2540 2550
THTEELSHRG APHTTTMTTT MTLEGEAKNV QTGLTESPVL LETLAEIFDT
2560 2570 2580 2590 2600
PASKVTRADL TSAVTASEMK SQVKEDSLTG GPEKETGPCT SLGHCDKCIH
2610 2620 2630 2640 2650
VDMLEPNEHT PSCALVAPPT VKDNLCSVNN AGEKSVRPQE DWPPAAEVRL
2660 2670 2680 2690 2700
SDACVEESIS EGKAGILQFT PENSDSTLSR LPHQSVAGWG KSADSVQARL
2710 2720 2730 2740 2750
PVSGVRHTSA DTLDVGCPQL ESSREKASAE EEPHRERALS LKPQEREHHM
2760 2770 2780 2790 2800
LGFVEDGRSI LKSSLDKVHM NLQEVGDPSA GTGTKISIQN LIRRAILSEL
2810 2820 2830 2840 2850
PNEVSNVPSH GISPISNSSE VRAESGGDPF CITSFLHLLK QNQPPQETPG
2860 2870 2880 2890 2900
ISELAKVLTQ MDCDPEQRGL GSELLPPQLK NAFYKLLFDG YATEKDQAEA
2910 2920 2930 2940 2950
LGQTSCAVPK MAEEKPHVCS DLRNKEGHHC PLNPQAVGEA EVEPFSVHIA
2960 2970 2980
ALPGGEKLGE LCSEPPEHSE STSGSKERSS DSSSKEK
Length:2,987
Mass (Da):331,491
Last modified:October 29, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1944918A507D9BB2
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 13 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q91ZU6DYST_MOUSE
Dystonin
Dst Bpag1, Macf2
7,393Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R1P5S4R1P5_MOUSE
Dystonin
Dst
7,717Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9Q9X1E9Q9X1_MOUSE
Dystonin
Dst
7,406Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WSP0A0A087WSP0_MOUSE
Dystonin
Dst
5,175Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R1Y6S4R1Y6_MOUSE
Dystonin
Dst
1,638Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WRB8A0A087WRB8_MOUSE
Dystonin
Dst
1,471Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R2A8S4R2A8_MOUSE
Dystonin
Dst
262Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R2C6S4R2C6_MOUSE
Dystonin
Dst
259Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1D5RLZ3A0A1D5RLZ3_MOUSE
Dystonin
Dst
1,674Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0A6YXR1A0A0A6YXR1_MOUSE
Dystonin
Dst
282Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei2987Imported1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000185897; ENSMUSP00000139888; ENSMUSG00000026131

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

SMRiA0A087WPR7
ModBaseiSearch...

Proteomic databases

jPOSTiA0A087WPR7
ProteomicsDBi348986

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
31066, 184 antibodies from 22 providers

Genome annotation databases

EnsembliENSMUST00000185897; ENSMUSP00000139888; ENSMUSG00000026131

Organism-specific databases

MGIiMGI:104627, Dst
VEuPathDBiHostDB:ENSMUSG00000026131

Phylogenomic databases

GeneTreeiENSGT00940000155008
HOGENOMiCLU_000015_3_0_1

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Dst, mouse

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000026131, Expressed in skin of back and 301 other tissues

Family and domain databases

Gene3Di3.90.1290.10, 2 hits
InterProiView protein in InterPro
IPR041615, Desmoplakin_SH3
IPR041573, Desmoplakin_Spectrin-like
IPR043197, Plakin
IPR035915, Plakin_repeat_sf
IPR001101, Plectin_repeat
IPR001452, SH3_domain
IPR018159, Spectrin/alpha-actinin
IPR002017, Spectrin_repeat
PANTHERiPTHR23169, PTHR23169, 3 hits
PfamiView protein in Pfam
PF00681, Plectin, 1 hit
PF17902, SH3_10, 1 hit
PF00435, Spectrin, 1 hit
PF18373, Spectrin_like, 1 hit
SMARTiView protein in SMART
SM00250, PLEC, 9 hits
SM00150, SPEC, 4 hits
SUPFAMiSSF75399, SSF75399, 2 hits
PROSITEiView protein in PROSITE
PS50002, SH3, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A087WPR7_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A087WPR7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: January 19, 2022
This is version 45 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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