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Entry version 42 (29 Sep 2021)
Sequence version 1 (29 Oct 2014)
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Protein
Submitted name:

Ankyrin-3

Gene

Ank3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Ankyrin-3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ank3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:88026, Ank3

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSMUSG00000069601

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
A0A087WNU5

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
350972

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000069601, Expressed in ventral horn of spinal cord and 307 other tissues

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini2763 – 2847DeathInterPro annotationAdd BLAST85

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni227 – 255DisorderedSequence analysisAdd BLAST29
Regioni685 – 731DisorderedSequence analysisAdd BLAST47
Regioni815 – 953DisorderedSequence analysisAdd BLAST139
Regioni991 – 1071DisorderedSequence analysisAdd BLAST81
Regioni1085 – 1142DisorderedSequence analysisAdd BLAST58
Regioni1180 – 1220DisorderedSequence analysisAdd BLAST41
Regioni1290 – 1611DisorderedSequence analysisAdd BLAST322
Regioni1640 – 1719DisorderedSequence analysisAdd BLAST80
Regioni1741 – 1784DisorderedSequence analysisAdd BLAST44
Regioni1830 – 1966DisorderedSequence analysisAdd BLAST137
Regioni1978 – 2206DisorderedSequence analysisAdd BLAST229
Regioni2228 – 2306DisorderedSequence analysisAdd BLAST79
Regioni2321 – 2410DisorderedSequence analysisAdd BLAST90
Regioni2452 – 2577DisorderedSequence analysisAdd BLAST126
Regioni2697 – 2761DisorderedSequence analysisAdd BLAST65

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi685 – 719Basic and acidic residuesSequence analysisAdd BLAST35
Compositional biasi820 – 837Basic and acidic residuesSequence analysisAdd BLAST18
Compositional biasi838 – 854Polar residuesSequence analysisAdd BLAST17
Compositional biasi927 – 953Basic and acidic residuesSequence analysisAdd BLAST27
Compositional biasi1020 – 1046Basic and acidic residuesSequence analysisAdd BLAST27
Compositional biasi1053 – 1070Basic and acidic residuesSequence analysisAdd BLAST18
Compositional biasi1114 – 1142Polar residuesSequence analysisAdd BLAST29
Compositional biasi1290 – 1326Basic and acidic residuesSequence analysisAdd BLAST37
Compositional biasi1327 – 1344Polar residuesSequence analysisAdd BLAST18
Compositional biasi1371 – 1390Polar residuesSequence analysisAdd BLAST20
Compositional biasi1407 – 1428Polar residuesSequence analysisAdd BLAST22
Compositional biasi1433 – 1457Basic and acidic residuesSequence analysisAdd BLAST25
Compositional biasi1468 – 1482Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi1496 – 1520Polar residuesSequence analysisAdd BLAST25
Compositional biasi1562 – 1576Polar residuesSequence analysisAdd BLAST15
Compositional biasi1577 – 1599Basic and acidic residuesSequence analysisAdd BLAST23
Compositional biasi1684 – 1715Polar residuesSequence analysisAdd BLAST32
Compositional biasi1741 – 1762Polar residuesSequence analysisAdd BLAST22
Compositional biasi1830 – 1883Polar residuesSequence analysisAdd BLAST54
Compositional biasi1908 – 1934Basic and acidic residuesSequence analysisAdd BLAST27
Compositional biasi2025 – 2040Basic and acidic residuesSequence analysisAdd BLAST16
Compositional biasi2063 – 2095Polar residuesSequence analysisAdd BLAST33
Compositional biasi2151 – 2186Basic and acidic residuesSequence analysisAdd BLAST36
Compositional biasi2244 – 2260Basic and acidic residuesSequence analysisAdd BLAST17
Compositional biasi2267 – 2290Polar residuesSequence analysisAdd BLAST24
Compositional biasi2341 – 2358Polar residuesSequence analysisAdd BLAST18
Compositional biasi2371 – 2410Polar residuesSequence analysisAdd BLAST40
Compositional biasi2474 – 2524Polar residuesSequence analysisAdd BLAST51
Compositional biasi2525 – 2540Basic and acidic residuesSequence analysisAdd BLAST16
Compositional biasi2556 – 2573Basic and acidic residuesSequence analysisAdd BLAST18
Compositional biasi2697 – 2712Basic and acidic residuesSequence analysisAdd BLAST16
Compositional biasi2713 – 2735Polar residuesSequence analysisAdd BLAST23

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT01040000242009

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000134_29_1_1

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A0A087WNU5

Family and domain databases

Conserved Domains Database

More...
CDDi
cd08803, Death_ank3, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.533.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037971, Ank3_Death
IPR040745, Ankyrin_UPA
IPR011029, DEATH-like_dom_sf
IPR000488, Death_domain

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00531, Death, 1 hit
PF17809, UPA_2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00005, DEATH, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47986, SSF47986, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50017, DEATH_DOMAIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

This entry has 1 described isoform and 24 potential isoforms that are computationally mapped.Show allAlign All

A0A087WNU5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XFWLADCHQV LETVGLASQL YRELICVPYM AKFVVFAKTN DPVESSLRCF
60 70 80 90 100
CMTDDRVDKT LEQQENFEEV ARSKDIEVLE GKPIYVDCYG NLAPLTKGGQ
110 120 130 140 150
QLVFNFYSFK ENRLPFSIKI RDTSQEPCGR LSFLKEPKTT KGLPQTAVCN
160 170 180 190 200
LNITLPAHKK ETESDQDDEA EKADRRQSFA SLALRKRYSY LTEPSMIERS
210 220 230 240 250
SGTARSLPTT YSHKPFFSTR PYQSWTTAPI TVPGPAKSGS LSSSPSNTPS
260 270 280 290 300
ASPLKSIWSV STPSPIKSTL GASTTSSVKS ISDVASPIRS FRTVSSPIKT
310 320 330 340 350
VVSPSPYNPQ VASGTLGRVP TITEATPIKG LAPNSTFSSR TSPVTTAGSL
360 370 380 390 400
LERSSITMTP PASPKSNITM YSSSLPFKSI ITSATPLISS PLKSVVSPTK
410 420 430 440 450
SAADVISTAK ATMASSLSSP LKQMSGHAEV ALVNGSVSPL KYPSSSALIN
460 470 480 490 500
GCKATATLQD KISTATNAVS SVVSAASDTV EKALSTTTAM PFSPLRSYVS
510 520 530 540 550
AAPSAFQSLR TPSASALYTS LGSSIAATTS SVTSSIITVP VYSVVNVLPE
560 570 580 590 600
PALKKLPDSN SFTKSAAALL SPIKTLTTET RPQPHFNRTS SPVKSSLFLA
610 620 630 640 650
SSALKPSVPS SLSSSQEILK DVAEMKEDLM RMTAILQTDV PEEKPFQTDL
660 670 680 690 700
PREGRIDDEE PFKIVEKVKE DLVKVSEILK KDVCVESKGP PKSPKSDKGH
710 720 730 740 750
SPEDDWTEFS SEEIREARQA AASHAPSLPE RVHGKANLTR VIDYLTNDIG
760 770 780 790 800
SSSLTNLKYK FEEAKKDGEE RQKRILKPAM ALQEHKLKMP PASMRPSTSE
810 820 830 840 850
KELCKMADSF FGADAILESP DDFSQHDQDK SPLSDSGFET RSEKTPSAPQ
860 870 880 890 900
SAESTGPKPL FHEVPIPPVI TETRTEVVHV IRSYEPSSGE IPQSQPEDPV
910 920 930 940 950
SPKPSPTFME LEPKPTTSSI KEKVKAFQMK ASSEEEDHSR VLSKGMRVKE
960 970 980 990 1000
ETHITTTTRM VYHSPPGGEC ASERIEETMS VHDIMKAFQS GRDPSKELAG
1010 1020 1030 1040 1050
LFEHKSAMSP DVAKSAAETS AQHAEKDSQM KPKLERIIEV HIEKGNQAEP
1060 1070 1080 1090 1100
TEVIIRETKK HPEKEVSVYQ KDLSRGNINL RDFLPEKHDA FPCPEEQGQQ
1110 1120 1130 1140 1150
EEEELAAEES LPSYLESSRV NTPGSQEEDS RPSSAQLLSD DSYKTLKLLS
1160 1170 1180 1190 1200
QHSVEYHDDE LSDLRGESYR FAEKMLLSEK LDVSHSDTEE SVTDHAGPPS
1210 1220 1230 1240 1250
SELQGSDKRS REKVATAPPK EILSKIYKDV SENGLGRVSK DEHFEKLTVL
1260 1270 1280 1290 1300
HYSGNVSGPK HAMWMHLSED RLDRGREKLM YEDRVDRTVK EAEEKLTEVS
1310 1320 1330 1340 1350
QFFRDKTEKL NDELQSPEKK PRPKNGKDYS SQSSTSSSPE KVLTELLASN
1360 1370 1380 1390 1400
DEWVKARQRG PDGQSVPQAE DRKAPSRSNS PENRVPTQQS EDDQPPEEAK
1410 1420 1430 1440 1450
RTVVAQSRGQ EGPQSGFQLK QSKLSSIRLK FEQGARAKSK DPPHEEKHLD
1460 1470 1480 1490 1500
GPSRIPVKKT QETKLPTHPG FAREKQQKAV DPLEERVPVQ NDVTVFKADH
1510 1520 1530 1540 1550
AQSNEIVTSK SGSGNGKSHR TEMLSKAMPD FFPEQQVEDS ACPITSDLET
1560 1570 1580 1590 1600
KGPWDRKVFR TWESSGANNT KAQKEQLSHV LVHDIRENHA GRPDDSENGD
1610 1620 1630 1640 1650
PKSGFMYVTE REHKMLTNGS LSEIKEMSVK SPSKKVLYRE YIVKDGDPPS
1660 1670 1680 1690 1700
SALNHPPRRS ESSLASHIPI RVTDERRMLS SNIPDGFCEQ STFPKQELSP
1710 1720 1730 1740 1750
RVSRPSMSEG VVESQHFNSV DDEKVTYSEI SKVSKHQSYL ALDETETSPT
1760 1770 1780 1790 1800
KSPDSLEFSP GKDSPSSDVF DHGSVDGLEK TEGGKEIKTL PVYVSFVQVG
1810 1820 1830 1840 1850
KQYEKELQPG GVKKIISQEC KTVQEARGTF YTARQQKQPP SPQGSPEDDT
1860 1870 1880 1890 1900
LEQVSFLDSS GKSPLTPETP SSEEVSYEFT SKTPDSLIAF IPGQPSPIPE
1910 1920 1930 1940 1950
VSEESEEEEP KSAPLRQVTV EKETDRDVSK DSIQRPKCNR VAYIEFPPPP
1960 1970 1980 1990 2000
PLDADQMESD KKHQYLPERE VDMMEVSLQD ESDKYQLAEP VIRVQPPSPV
2010 2020 2030 2040 2050
PPGAEASDSS DDESLYQPVP VKKYTFKLKE VDEGQKDTAK SKTAATKASN
2060 2070 2080 2090 2100
QKEADGNGRE GESGLDSPQN ETAQNGNNDQ SVTECSIATT AEFSHDTDAT
2110 2120 2130 2140 2150
EIDSLDGYDL QDEDDGLTES DSKLPSQTID TKKDVWTEGI LKPADRSFSQ
2160 2170 2180 2190 2200
SKLEVIEEEE GKVGLDEEKP SPSKSPSSDR TPEKADPKSG AQFFTLEGRH
2210 2220 2230 2240 2250
PDRSVLPDTY FSYKVDEEFA TPFKTVATKG LDFDPWPNNR GDNEVFDGKS
2260 2270 2280 2290 2300
REDDTKPFGL AVDDRSPATT PDTTPARTPT DESTPTSEPN PFPFHEGKMF
2310 2320 2330 2340 2350
EMTRSGAIDM SKRDFVEERL QFFQIGEHTP EGKSGAQGEG DMVTDTPQPQ
2360 2370 2380 2390 2400
SGDTSVDTNL ERDVVAPSVD PNPSIPSNGE CQEGTACSGS LEKSAAATNT
2410 2420 2430 2440 2450
SKVDPKSRTP IKMGISASTM TMKKEGSGEV TDKTEAVVTS CQGLENEIVK
2460 2470 2480 2490 2500
EISSAPSSQV GIRPQEKHDF QKDNFNNNNN LDASTMQTDN STSHIVLTGR
2510 2520 2530 2540 2550
AASTCTTEEA NPVKGSGKSP GTQGHSSRES RKEPIGLRRK SKLPIKATAP
2560 2570 2580 2590 2600
KDVFPPNHKA DSKTGKPRQV GQYEKHKALP TSSCLDAKSR IPVKNTHREN
2610 2620 2630 2640 2650
LVSVRKACAT QKRGQPERGK AKQPPSKLPV KVRSTRVTVT TTNTSTTTTT
2660 2670 2680 2690 2700
TTTTTTTTTV KVTESQLKEV CKHPIEYFKG ISGETLKLVD RLTEEDKKMQ
2710 2720 2730 2740 2750
SELSDEEEST SRNTSLSETS RGGQPSVTTK SARNKKTEAP PLKSKRGKAG
2760 2770 2780 2790 2800
SRRTGPQSPC ERTDIRMAIV ADHLGLSWTE LARELNFSVD EINQIRVENP
2810 2820 2830 2840 2850
NSLISQSFML LKKWVTRDGK NATTDALTSV LTKINRIDIV TLLEGPIFDY
2860 2870
GNISGTRSFA DENNVFHDPV D
Length:2,871
Mass (Da):315,538
Last modified:October 29, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8022DA31269C60C1
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 24 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G5E8K5ANK3_MOUSE
Ankyrin-3
Ank3
1,961Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G5E8K2G5E8K2_MOUSE
Ankyrin-3
Ank3
1,940Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G5E8K3G5E8K3_MOUSE
Ankyrin-3
Ank3
1,943Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R2S8S4R2S8_MOUSE
Ankyrin-3
Ank3
1,985Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R236S4R236_MOUSE
Ankyrin-3
Ank3
1,181Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R2K9S4R2K9_MOUSE
Ankyrin-3
Ank3
2,622Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R1S2S4R1S2_MOUSE
Ankyrin-3
Ank3
1,807Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1W2P812A0A1W2P812_MOUSE
Ankyrin-3
Ank3
1,758Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R165S4R165_MOUSE
Ankyrin-3
Ank3
1,174Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R2J6S4R2J6_MOUSE
Ankyrin-3
Ank3
1,157Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1
Non-terminal residuei2871Imported1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000186247; ENSMUSP00000139496; ENSMUSG00000069601

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

Proteomic databases

jPOSTiA0A087WNU5
ProteomicsDBi350972

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
4197, 290 antibodies

Genome annotation databases

EnsembliENSMUST00000186247; ENSMUSP00000139496; ENSMUSG00000069601

Organism-specific databases

MGIiMGI:88026, Ank3
VEuPathDBiHostDB:ENSMUSG00000069601

Phylogenomic databases

GeneTreeiENSGT01040000242009
HOGENOMiCLU_000134_29_1_1
PhylomeDBiA0A087WNU5

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Ank3, mouse

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000069601, Expressed in ventral horn of spinal cord and 307 other tissues

Family and domain databases

CDDicd08803, Death_ank3, 1 hit
Gene3Di1.10.533.10, 1 hit
InterProiView protein in InterPro
IPR037971, Ank3_Death
IPR040745, Ankyrin_UPA
IPR011029, DEATH-like_dom_sf
IPR000488, Death_domain
PfamiView protein in Pfam
PF00531, Death, 1 hit
PF17809, UPA_2, 1 hit
SMARTiView protein in SMART
SM00005, DEATH, 1 hit
SUPFAMiSSF47986, SSF47986, 1 hit
PROSITEiView protein in PROSITE
PS50017, DEATH_DOMAIN, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A087WNU5_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A087WNU5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: September 29, 2021
This is version 42 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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