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Protein

UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Gene

murG

Organism
Bifidobacterium longum subsp. longum
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).UniRule annotationSAAS annotation

Catalytic activityi

UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol.UniRule annotationSAAS annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotationSAAS annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotationSAAS annotationImported, Transferase
Biological processCell cycle, Cell divisionUniRule annotationSAAS annotation, Cell shape, Cell wall biogenesis/degradationUniRule annotationSAAS annotation, Peptidoglycan synthesisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00219

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferaseUniRule annotationSAAS annotation (EC:2.4.1.227UniRule annotationSAAS annotation)
Alternative name(s):
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferaseUniRule annotation
Gene namesi
Name:murGUniRule annotation
ORF Names:BBL306_1357Imported, BL1206_1391Imported, BLOI2_0189Imported, NL89_07300Imported
OrganismiBifidobacterium longum subsp. longumImported
Taxonomic identifieri1679 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaBifidobacterialesBifidobacteriaceaeBifidobacterium
Proteomesi
  • UP000030357 Componenti: Unassembled WGS sequence
  • UP000037245 Componenti: Unassembled WGS sequence
  • UP000065375 Componenti: Chromosome
  • UP000095109 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini8 – 145Glyco_transf_28InterPro annotationAdd BLAST138
Domaini205 – 369Glyco_tran_28_CInterPro annotationAdd BLAST165

Sequence similaritiesi

Belongs to the glycosyltransferase 28 family. MurG subfamily.UniRule annotationSAAS annotation

Family and domain databases

CDDicd03785 GT1_MurG, 1 hit
HAMAPiMF_00033 MurG, 1 hit
InterProiView protein in InterPro
IPR006009 GlcNAc_MurG
IPR007235 Glyco_trans_28_C
IPR004276 GlycoTrans_28_N
PfamiView protein in Pfam
PF04101 Glyco_tran_28_C, 1 hit
PF03033 Glyco_transf_28, 1 hit

Sequencei

Sequence statusi: Complete.

A0A087ATY5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQGTPHIVL AGGGTAGHVN PLLAVAGAIR DIEPTAQVTV IGTAVGLEKD
60 70 80 90 100
LVPEAGYELD TIEKVPFPRR PNLYMLRFPA KWKRETAKVR SILETRHADV
110 120 130 140 150
VAGFGGYASA PVYATAHKMG IPIAIHEQNA RAGMANKLGA RWADFIGTVY
160 170 180 190 200
EGTGLKPRAG ADVERVGLPL RPAIASLTKR IGDDRAAVRR ESAAQLGVDP
210 220 230 240 250
NRPLVLVTGG SLGAQSLNRA IASSAADLLA HAQIIHLTGR GKISEVRELV
260 270 280 290 300
TASAGADVLT GIGPESAGQG DYHTAEYLER IDLAFACADL VICRAGAGSV
310 320 330 340 350
SELAALGLPA IYVPLPIGNG EQRFNAEPVV NAGGGLLVAD KDLTPQWVHE
360 370 380 390
HVPDLLADHE RLAEFGRKAW EYGIRNAAEI MARHVLQLAE PSK
Length:393
Mass (Da):41,511
Last modified:October 29, 2014 - v1
Checksum:iDAF16113F5923AAD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP011965 Genomic DNA Translation: ALO74886.1
CP016019 Genomic DNA Translation: AOP01429.1
JRWN01000011 Genomic DNA Translation: KHD94979.1
LFDU01000002 Genomic DNA Translation: KOP63307.1
RefSeqiWP_007052550.1, NZ_MLZK01000012.1

Genome annotation databases

EnsemblBacteriaiALO72816; ALO72816; B8809_1145
ALO74886; ALO74886; BBL306_1357
AOP01429; AOP01429; BL1206_1391
KHD94979; KHD94979; NL89_07300
KOP63307; KOP63307; BLOI2_0189
PATRICifig|1679.10.peg.1488

Similar proteinsi

Entry informationi

Entry nameiA0A087ATY5_BIFLN
AccessioniPrimary (citable) accession number: A0A087ATY5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: July 18, 2018
This is version 28 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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