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Protein
Submitted name:

NeuroPeptide Receptor family

Gene

npr-4

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
NeuroPeptide Receptor familyImported
Gene namesi
Name:npr-4Imported
ORF Names:C16D6.2Imported, CELE_C16D6.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiC16D6.2c ; CE50063 ; WBGene00007635 ; npr-4

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei46 – 74HelicalSequence analysisAdd BLAST29
Transmembranei86 – 111HelicalSequence analysisAdd BLAST26
Transmembranei123 – 143HelicalSequence analysisAdd BLAST21
Transmembranei164 – 184HelicalSequence analysisAdd BLAST21
Transmembranei212 – 236HelicalSequence analysisAdd BLAST25
Transmembranei279 – 299HelicalSequence analysisAdd BLAST21
Transmembranei314 – 338HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliA0A078BS36
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini66 – 335G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST270

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
GeneTreeiENSGT00920000148949

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000611 NPY_rcpt
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR01012 NRPEPTIDEYR
SMARTiView protein in SMART
SM01381 7TM_GPCR_Srsx, 1 hit
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

A0A078BS36-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLLEIGTITI GNITRARKFG ERMNGSDCLN LNSELWLYRE DLSSRWYIML
60 70 80 90 100
VFAFLYLIII AAGIIGNSCV ILAITRNKSL QTVPNLFILS LSCSDIVVCC
110 120 130 140 150
TSATITPITA FKKEWIFGEA LCRIAPFIAG ISLCFSTFTL TAISIDRYIL
160 170 180 190 200
IRFPMRKPIT HYQAVGVIAI ICAFAATITS PIMFKQKLGE FENFCGQYCT
210 220 230 240 250
ENWGANESQR KIYGAALMFL QLVIPLTIII ISYTAISLKI GQSMILKGAK
260 270 280 290 300
KQKTDNWEME LSDQQRIAVK RRQRTNRMLI GMVVAFACSW IWSVTFNILR
310 320 330 340 350
DYEYLPELIK TQEYIFGIAT HCIAMTSTVW NPLLYAVLNL QLRAAFIDLM
360 370 380 390
PHWLRRHLNL EGDNSSPLLN HPTMTITNKP SKQHTLIPAM DNHTCQQV
Length:398
Mass (Da):45,177
Last modified:October 29, 2014 - v1
Checksum:i73094AB8E0BF6305
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0K3AYF5A0A0K3AYF5_CAEEL
NeuroPeptide Receptor family
npr-4 C16D6.2, CELE_C16D6.2
490Annotation score:
O62062O62062_CAEEL
NeuroPeptide Receptor family
npr-4 C16D6.2, CELE_C16D6.2
468Annotation score:
A0A078BTK0A0A078BTK0_CAEEL
NeuroPeptide Receptor family
npr-4 C16D6.2, CELE_C16D6.2
376Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA Translation: CDX47441.1
RefSeqiNP_001294803.1, NM_001307874.1
UniGeneiCel.11352

Genome annotation databases

EnsemblMetazoaiC16D6.2c; C16D6.2c; WBGene00007635
GeneIDi182684

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA Translation: CDX47441.1
RefSeqiNP_001294803.1, NM_001307874.1
UniGeneiCel.11352

3D structure databases

ProteinModelPortaliA0A078BS36
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC16D6.2c; C16D6.2c; WBGene00007635
GeneIDi182684

Organism-specific databases

CTDi182684
WormBaseiC16D6.2c ; CE50063 ; WBGene00007635 ; npr-4

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
GeneTreeiENSGT00920000148949

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000611 NPY_rcpt
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR01012 NRPEPTIDEYR
SMARTiView protein in SMART
SM01381 7TM_GPCR_Srsx, 1 hit
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A078BS36_CAEEL
AccessioniPrimary (citable) accession number: A0A078BS36
Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: October 10, 2018
This is version 27 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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