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Protein

Probable L-aspartate decarboxylase

Gene

mfnA

Organism
Archaeoglobus fulgidus DSM 8774
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.UniRule annotation

Catalytic activityi

L-aspartate = beta-alanine + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

Pathwayi: coenzyme A biosynthesis

This protein is involved in the pathway coenzyme A biosynthesis, which is part of Cofactor biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway coenzyme A biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylaseUniRule annotation, Lyase
LigandPyridoxal phosphateUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00241

Names & Taxonomyi

Protein namesi
Recommended name:
Probable L-aspartate decarboxylaseUniRule annotation (EC:4.1.1.11UniRule annotation)
Short name:
ADCUniRule annotation
Gene namesi
Name:mfnAUniRule annotation
ORF Names:AFULGI_00022680Imported
OrganismiArchaeoglobus fulgidus DSM 8774Imported
Taxonomic identifieri1344584 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus
Proteomesi
  • UP000028501 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei216N6-(pyridoxal phosphate)lysineUniRule annotation1

Structurei

3D structure databases

ProteinModelPortaliA0A075WIG8
SMRiA0A075WIG8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family. MfnA subfamily.UniRule annotation

Phylogenomic databases

KOiK18933
OrthoDBiPOG093Z06IK

Family and domain databases

Gene3Di3.40.640.10, 1 hit
3.90.1150.10, 2 hits
HAMAPiMF_01610 MfnA_decarbox, 1 hit
InterProiView protein in InterPro
IPR020931 MfnA
IPR002129 PyrdxlP-dep_de-COase
IPR015424 PyrdxlP-dep_Trfase
IPR015422 PyrdxlP-dep_Trfase_dom1
IPR015421 PyrdxlP-dep_Trfase_major
IPR021115 Pyridoxal-P_BS
PfamiView protein in Pfam
PF00282 Pyridoxal_deC, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
TIGRFAMsiTIGR03812 tyr_de_CO2_Arch, 1 hit
PROSITEiView protein in PROSITE
PS00392 DDC_GAD_HDC_YDC, 1 hit

Sequencei

Sequence statusi: Complete.

A0A075WIG8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDIIEELRAY REKDIPYSRV LSSMCTVPHP VAVEAHRMFI ETNLGDPGIF
60 70 80 90 100
RGTVELEAKL MRLIGDILHC ETPAGYICSG GTEANIQGIR AARNVQKKEN
110 120 130 140 150
PNIVIPKTAH FSFEKIGDIL GVKIKRAGVD EEYKVDVGQV EDLMDENTVA
160 170 180 190 200
IVGIAGTTEL GQIDPIVELS KLAEERQVEL HVDAAFGGLV IPFMDNPYPF
210 220 230 240 250
DFQNRGVSSI TIDPHKMGMA TIPAGGIIFR NESYLRALEV ETPYLTSKTQ
260 270 280 290 300
FTLTGTRPGT GVASAYAVLK SLGFEGMREV VKNCLKNTRI LVEEMRDLGF
310 320 330 340 350
EPVIEPVMNV VSFRTDEAER IKEELYRMRW VISTIREPKA IRFVVMPHVT
360
EEVIKNFISD FRKVLRR
Length:367
Mass (Da):41,171
Last modified:October 29, 2014 - v1
Checksum:i97FE8070AF75EE07
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP006577 Genomic DNA Translation: AIG98994.1
RefSeqiWP_010879496.1, NZ_CP006577.1

Genome annotation databases

EnsemblBacteriaiAIG98994; AIG98994; AFULGI_00022680
GeneIDi24795749
KEGGiafg:AFULGI_00022680

Similar proteinsi

Entry informationi

Entry nameiA0A075WIG8_ARCFL
AccessioniPrimary (citable) accession number: A0A075WIG8
Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: February 28, 2018
This is version 20 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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