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Entry version 43 (07 Apr 2021)
Sequence version 3 (27 May 2015)
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Protein
Submitted name:

Neuroblastoma breakpoint family member 10

Gene

NBPF10

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Neuroblastoma breakpoint family member 10Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NBPF10Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:31992, NBPF10

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000271425.6

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000271425

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PeptideAtlas

More...
PeptideAtlasi
A0A075B762

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000271425, Expressed in sural nerve and 115 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A0A075B762, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000463957

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini165 – 259OlduvaiInterPro annotationAdd BLAST95
Domaini436 – 528OlduvaiInterPro annotationAdd BLAST93
Domaini529 – 600OlduvaiInterPro annotationAdd BLAST72
Domaini601 – 692OlduvaiInterPro annotationAdd BLAST92
Domaini695 – 750OlduvaiInterPro annotationAdd BLAST56
Domaini751 – 843OlduvaiInterPro annotationAdd BLAST93
Domaini844 – 936OlduvaiInterPro annotationAdd BLAST93
Domaini939 – 994OlduvaiInterPro annotationAdd BLAST56
Domaini995 – 1087OlduvaiInterPro annotationAdd BLAST93
Domaini1088 – 1180OlduvaiInterPro annotationAdd BLAST93
Domaini1183 – 1238OlduvaiInterPro annotationAdd BLAST56
Domaini1239 – 1331OlduvaiInterPro annotationAdd BLAST93
Domaini1332 – 1424OlduvaiInterPro annotationAdd BLAST93
Domaini1427 – 1482OlduvaiInterPro annotationAdd BLAST56
Domaini1483 – 1575OlduvaiInterPro annotationAdd BLAST93
Domaini1576 – 1668OlduvaiInterPro annotationAdd BLAST93
Domaini1671 – 1726OlduvaiInterPro annotationAdd BLAST56
Domaini1727 – 1819OlduvaiInterPro annotationAdd BLAST93
Domaini1820 – 1912OlduvaiInterPro annotationAdd BLAST93
Domaini1915 – 1970OlduvaiInterPro annotationAdd BLAST56
Domaini1971 – 2063OlduvaiInterPro annotationAdd BLAST93
Domaini2064 – 2156OlduvaiInterPro annotationAdd BLAST93
Domaini2159 – 2214OlduvaiInterPro annotationAdd BLAST56
Domaini2215 – 2307OlduvaiInterPro annotationAdd BLAST93
Domaini2308 – 2400OlduvaiInterPro annotationAdd BLAST93
Domaini2403 – 2458OlduvaiInterPro annotationAdd BLAST56
Domaini2459 – 2551OlduvaiInterPro annotationAdd BLAST93
Domaini2552 – 2644OlduvaiInterPro annotationAdd BLAST93
Domaini2647 – 2702OlduvaiInterPro annotationAdd BLAST56
Domaini2703 – 2795OlduvaiInterPro annotationAdd BLAST93
Domaini2796 – 2888OlduvaiInterPro annotationAdd BLAST93
Domaini2891 – 2946OlduvaiInterPro annotationAdd BLAST56
Domaini2947 – 3039OlduvaiInterPro annotationAdd BLAST93
Domaini3040 – 3132OlduvaiInterPro annotationAdd BLAST93
Domaini3135 – 3190OlduvaiInterPro annotationAdd BLAST56
Domaini3191 – 3283OlduvaiInterPro annotationAdd BLAST93
Domaini3284 – 3376OlduvaiInterPro annotationAdd BLAST93
Domaini3379 – 3434OlduvaiInterPro annotationAdd BLAST56
Domaini3435 – 3527OlduvaiInterPro annotationAdd BLAST93
Domaini3528 – 3620OlduvaiInterPro annotationAdd BLAST93
Domaini3623 – 3696OlduvaiInterPro annotationAdd BLAST74
Domaini3697 – 3795OlduvaiInterPro annotationAdd BLAST99

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni161 – 200DisorderedSequence analysisAdd BLAST40
Regioni451 – 475DisorderedSequence analysisAdd BLAST25
Regioni520 – 566DisorderedSequence analysisAdd BLAST47
Regioni830 – 868DisorderedSequence analysisAdd BLAST39
Regioni1073 – 1109DisorderedSequence analysisAdd BLAST37
Regioni1242 – 1261DisorderedSequence analysisAdd BLAST20
Regioni1318 – 1353DisorderedSequence analysisAdd BLAST36
Regioni1562 – 1600DisorderedSequence analysisAdd BLAST39
Regioni1806 – 1844DisorderedSequence analysisAdd BLAST39
Regioni2050 – 2088DisorderedSequence analysisAdd BLAST39
Regioni2294 – 2332DisorderedSequence analysisAdd BLAST39
Regioni2538 – 2576DisorderedSequence analysisAdd BLAST39
Regioni2782 – 2820DisorderedSequence analysisAdd BLAST39
Regioni3026 – 3064DisorderedSequence analysisAdd BLAST39
Regioni3194 – 3213DisorderedSequence analysisAdd BLAST20
Regioni3270 – 3308DisorderedSequence analysisAdd BLAST39
Regioni3514 – 3552DisorderedSequence analysisAdd BLAST39
Regioni3684 – 3716DisorderedSequence analysisAdd BLAST33

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili75 – 119Sequence analysisAdd BLAST45
Coiled coili292 – 312Sequence analysisAdd BLAST21
Coiled coili346 – 390Sequence analysisAdd BLAST45

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi179 – 200PolyampholyteSequence analysisAdd BLAST22
Compositional biasi539 – 553PolyampholyteSequence analysisAdd BLAST15
Compositional biasi832 – 846BasicSequence analysisAdd BLAST15
Compositional biasi847 – 868PolyampholyteSequence analysisAdd BLAST22
Compositional biasi1076 – 1090BasicSequence analysisAdd BLAST15
Compositional biasi1091 – 1109PolyampholyteSequence analysisAdd BLAST19
Compositional biasi1320 – 1334BasicSequence analysisAdd BLAST15
Compositional biasi1335 – 1353PolyampholyteSequence analysisAdd BLAST19
Compositional biasi1564 – 1578BasicSequence analysisAdd BLAST15
Compositional biasi1579 – 1600PolyampholyteSequence analysisAdd BLAST22
Compositional biasi1808 – 1822BasicSequence analysisAdd BLAST15
Compositional biasi1823 – 1844PolyampholyteSequence analysisAdd BLAST22
Compositional biasi2052 – 2066BasicSequence analysisAdd BLAST15
Compositional biasi2067 – 2088PolyampholyteSequence analysisAdd BLAST22
Compositional biasi2296 – 2310BasicSequence analysisAdd BLAST15
Compositional biasi2311 – 2332PolyampholyteSequence analysisAdd BLAST22
Compositional biasi2540 – 2554BasicSequence analysisAdd BLAST15
Compositional biasi2555 – 2576PolyampholyteSequence analysisAdd BLAST22
Compositional biasi2784 – 2798BasicSequence analysisAdd BLAST15
Compositional biasi2799 – 2820PolyampholyteSequence analysisAdd BLAST22
Compositional biasi3028 – 3042BasicSequence analysisAdd BLAST15
Compositional biasi3043 – 3064PolyampholyteSequence analysisAdd BLAST22
Compositional biasi3272 – 3286BasicSequence analysisAdd BLAST15
Compositional biasi3287 – 3308PolyampholyteSequence analysisAdd BLAST22
Compositional biasi3516 – 3530BasicSequence analysisAdd BLAST15
Compositional biasi3531 – 3552PolyampholyteSequence analysisAdd BLAST22
Compositional biasi3684 – 3699BasicSequence analysisAdd BLAST16

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysisARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502RU1I, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00420000029746

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_224329_0_0_1

Database of Orthologous Groups

More...
OrthoDBi
372685at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR010630, Olduvai_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06758, Olduvai, 42 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01148, DUF1220, 42 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51316, NBPF, 42 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

A0A075B762-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVVSAGPWSS EKAEMNILEI NETLRPQLAE KKQQFRSLKE KCFLTQLAGF
60 70 80 90 100
LANRQKKYKY EECKDLIKFM LRNERQFKEE KLAEQLKQAE ELRQYKVLVH
110 120 130 140 150
SQERELTQLR EKLREGRDAS RSLYEHLQAL LTPDEPDKSQ GQDLQEQLAE
160 170 180 190 200
GCRLAQHLVQ KLSPENDEDE DEDVQVEEAE KVLESSAPRE VQKAEESKVP
210 220 230 240 250
EDSLEECAIT CSNSHGPCDS NQPHKNIKIT FEEDEVNSTL VVDRESSHDE
260 270 280 290 300
CQDALNILPV PGPTSSATNV SMVVSAGPLS SEKAEMNILE INEKLRPQLA
310 320 330 340 350
EKKQQFRNLK EKCFLTQLSG FLANQQKKYK YEECKDLIKF MLRNERQFKE
360 370 380 390 400
EKLAEQLKQA EELRQYKVLV HAQERELTQL KEKLREGRDA SRSLNEHLQA
410 420 430 440 450
LLTPYEPDKS QGQDLQEQLA EGCRLAQHLV QKLSPENDND DDEDVQVEVA
460 470 480 490 500
EKVQKSSAPR EMQKAEEKEV PEDSLEECAI TYSNSHGSYD SNQPHRKTKI
510 520 530 540 550
TFEEDKVDST LIGSSSHVEW EDAVHIIPEN ESDDEEEEEK GPVSPRNLQE
560 570 580 590 600
SEEEEVPQES WDEGYSTLSI PPEMLASYQS YSSTFHSLEE QQVCMAVDIG
610 620 630 640 650
RHRWDQVKKE DQEATGPRLS RELLDEKGPE VLQDSQDRCY STPSGCLELT
660 670 680 690 700
DSCQPYRSAF YILEQQRVGL AIDMDEIEKY QEVEEDQDPS CPRLSRELLD
710 720 730 740 750
EKEPEVLQDS LDRCYSTPSG YLELPDLGQP YSSAVYSLEE QYLGLALDVD
760 770 780 790 800
RIKKDQEEEE DQGPPCPRLS RELLEVVEPE VLQDSLDRCY STPSSCLEQP
810 820 830 840 850
DSCQPYGSSF YALEEKHVGF SLDVGEIEKK GKGKKRRGRR SKKERRRGRK
860 870 880 890 900
EGEEDQNPPC PRLSRELLDE KGPEVLQDSL DRCYSTPSGC LELTDSCQPY
910 920 930 940 950
RSAFYVLEQQ RVGFAFDMDE IEKYQEVEED QDPSCPRLSR ELLDEKEPEV
960 970 980 990 1000
LQDSLDRCYS TPSGYLELPD LGQPYSSAVY SLEEQYLGLA LDVDRIKKDE
1010 1020 1030 1040 1050
EEEEDQDPPC PRLSRELLEV VEPEVLQDSL DRCYSTPSSC LEQPDSCQPY
1060 1070 1080 1090 1100
GSSFYALEEN HVGFSLDVGE IEKKGKGKKR RGRRSKKERR RGRKEGEEDQ
1110 1120 1130 1140 1150
NPPCPRLSRE LLEEKGPEVL QDSLDRCYST PSGCLELTDS CQPYRSAFYV
1160 1170 1180 1190 1200
LEQQRVGFAV DMDEIEKYQE VEEDQDPSCP RLSRELLDEK EPEVLQDSLD
1210 1220 1230 1240 1250
RCYSTPSGYL ELPDLGQPYS SAVYSLEEQY LGLALDVDRI KKDEEEEEDQ
1260 1270 1280 1290 1300
DPPCPRLSRE LLEVVEPEVL QDSLDRCYST PSSCLEQPDS CQPYGSSFYA
1310 1320 1330 1340 1350
LEEKHVGFSL DVGEIEKKGK GKKRRGRRSK KERRRGRKEG EEDQNPPCPR
1360 1370 1380 1390 1400
LSRELLEEKG PEVLQDSLDR CYSTPSGCLE LTDSCQPYRS AFYVLEQQRV
1410 1420 1430 1440 1450
GFAVDMDEIE KYQEVEEDQD PSCPRLSREL LDEKEPEVLQ DSLDRCYSTP
1460 1470 1480 1490 1500
SGYLELPDLG QPYSSAVYSL EEQYLGLALD VDRIKKDEEE EEDQDPPCPR
1510 1520 1530 1540 1550
LSRELLEVVE PEVLQDSLDR CYSTPSSCLE QPDSCQPYGS SFYALEEKHV
1560 1570 1580 1590 1600
GFSLDVGEIE KKGKGKKRRG RRSKKERRRG RKEGEEDQNP PCPRLSRELL
1610 1620 1630 1640 1650
DEKGPEVLQD SLDRCYSTPS GCLELTDSCQ PYRSAFYVLE QQHVGLAVDM
1660 1670 1680 1690 1700
DEIEKYQEVE EDQDPSCPRL SRELLDEKEP EVLQDSLDRC YSTPSGYLEL
1710 1720 1730 1740 1750
PDLGQPYSSA VYSLEEQYLG LALDVDRIKK DQEEEEDQGP PCPRLSRELL
1760 1770 1780 1790 1800
EVVEPEVLQD SLDRCYSTPS SCLEQPDSCQ PYGSSFYALE EKHVGFSLDV
1810 1820 1830 1840 1850
GEIEKKGKGK KRRGRRSKKE RRRGRKEGEE DQNPPCPRLS RELLDEKGPE
1860 1870 1880 1890 1900
VLQDSLDRCY STPSGCLELT DSCQPYRSAF YVLEQQHVGL AVDMDEIEKY
1910 1920 1930 1940 1950
QEVEEDQDPS CPRLSRELLD EKEPEVLQDS LDRCYSTPSG YLELPDLGQP
1960 1970 1980 1990 2000
YSSAVYSLEE QYLGLALDVD RIKKDQEEEE DQGPPCPRLS RELLEVVEPE
2010 2020 2030 2040 2050
VLQDSLDRCY STPSSCLEQP DSCQPYGSSF YALEEKHVGF SLDVGEIEKK
2060 2070 2080 2090 2100
GKGKKRRGRR SKKERRRGRK EGEEDQNPPC PRLSRELLDE KGPEVLQDSL
2110 2120 2130 2140 2150
DRCYSTPSGC LELTDSCQPY RSAFYVLEQQ HVGLAVDMDE IEKYQEVEED
2160 2170 2180 2190 2200
QDPSCPRLSR ELLDEKEPEV LQDSLDRCYS TPSGYLELPD LGQPYSSAVY
2210 2220 2230 2240 2250
SLEEQYLGLA LDVDRIKKDQ EEEEDQGPPC PRLSRELLEV VEPEVLQDSL
2260 2270 2280 2290 2300
DRCYSTPSSC LEQPDSCQPY GSSFYALEEK HVGFSLDVGE IEKKGKGKKR
2310 2320 2330 2340 2350
RGRRSKKERR RGRKEGEEDQ NPPCPRLSRE LLDEKGPEVL QDSLDRCYST
2360 2370 2380 2390 2400
PSGCLELTDS CQPYRSAFYV LEQQHVGLAV DMDEIEKYQE VEEDQDPSCP
2410 2420 2430 2440 2450
RLSRELLDEK EPEVLQDSLD RCYSTPSGYL ELPDLGQPYS SAVYSLEEQY
2460 2470 2480 2490 2500
LGLALDVDRI KKDQEEEEDQ DPPCPRLSRE LLEVVEPEVL QDSLDRCYST
2510 2520 2530 2540 2550
PSSCLEQPDS CQPYGSSFYA LEEKHVGFSL DVGEIEKKGK GKKRRGRRSK
2560 2570 2580 2590 2600
KERRRGRKEG EEDQNPPCPR LSRELLDEKG PEVLQDSLDR CYSTPSGCLE
2610 2620 2630 2640 2650
LTDSCQPYRS AFYVLEQQHV GLAVDMDEIE KYQEVEEDQD PSCPRLSREL
2660 2670 2680 2690 2700
LDEKEPEVLQ DSLDRCYSTP SGYLELPDLG QPYSSAVYSL EEQYLGLALD
2710 2720 2730 2740 2750
VDRIKKDQEE EEDQGPPCPR LSRELLEVVE PEVLQDSLDR CYSTPSSCLE
2760 2770 2780 2790 2800
QPDSCQPYGS SFYALEEKHV GFSLDVGEIE KKGKGKKRRG RRSKKERRRG
2810 2820 2830 2840 2850
RKEGEEDQNP PCPRLSRELL DEKGPEVLQD SLDRCYSTPS GCLELTDSCQ
2860 2870 2880 2890 2900
PYRSAFYVLE QQHVGLAVDM DEIEKYQEVE EDQDPSCPRL SRELLDEKEP
2910 2920 2930 2940 2950
EVLQDSLDRC YSTPSGYLEL PDLGQPYSSA VYSLEEQYLG LALDVDRIKK
2960 2970 2980 2990 3000
DQEEEEDQGP PCPRLSRELL EVVEPEVLQD SLDRCYSTPS SCLEQPDSCQ
3010 3020 3030 3040 3050
PYGSSFYALE EKHVGFSLDV GEIEKKGKGK KRRGRRSKKE RRRGRKEGEE
3060 3070 3080 3090 3100
DQNPPCPRLS RELLDEKGPE VLQDSLDRCY STPSGCLELT DSCQPYRSAF
3110 3120 3130 3140 3150
YVLEQQHVGL AVDMDEIEKY QEVEEDQDPS CPRLSRELLD EKEPEVLQDS
3160 3170 3180 3190 3200
LDRCYSTPSG YLELPDLGQP YSSAVYSLEE QYLGLALDVD RIKKDEEEEE
3210 3220 3230 3240 3250
DQDPPCPRLS RELLEVVEPE VLQDSLDRCY STPSSCLEQP DSCQPYGSSF
3260 3270 3280 3290 3300
YALEEKHVGF SLDVGEIEKK GKGKKRRGRR SKKERRRGRK EGEEDQNPPC
3310 3320 3330 3340 3350
PRLSRELLDE KGPEVLQDSL DRCYSTPSGY LELTDSCQPY RSAFYVLEQQ
3360 3370 3380 3390 3400
HVGLAVDMDE IEKYQEVEED QDPSCPRLSR ELLDEKEPEV LQDSLDRCYS
3410 3420 3430 3440 3450
TPSGYLELPD LGQPYSSAVY SLEEQYLGLA LDVDRIKKDQ EEEEDQGPPC
3460 3470 3480 3490 3500
PRLSRELLEV VEPEVLQDSL DRCYSTPSSC LEQPDSCQPY GSSFYALEEK
3510 3520 3530 3540 3550
HVGFSLDVGE IEKKGKGKKR RGRRSKKERR RGRKEGEEDQ NPPCPRLSRE
3560 3570 3580 3590 3600
LLDEKGPEVL QDSLDRCYST PSGCLELCDS CQPYRSAFYV LEQQRVGLAV
3610 3620 3630 3640 3650
DMDEIEKYQE VEEDQDPSCP RLSRELLDEK EPEVLQDSLD RCYSTPSGYL
3660 3670 3680 3690 3700
ELPDLGQPYS SAVYSLEEQY LGLALDVDKI EKKGKGKKRR GRRSKKERRR
3710 3720 3730 3740 3750
GRKEGEEDQN PPCPRLNGVL MEVEEREVLQ DSLDRCYSTP SMYFELPDSF
3760 3770 3780 3790
QHYRSVFYSF EEQHISFALY VDNRFFTLTV TSLHLVFQMG VIFPQ
Length:3,795
Mass (Da):435,634
Last modified:May 27, 2015 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i04CD7F04467BA71E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q6P3W6NBPFA_HUMAN
Neuroblastoma breakpoint family mem...
NBPF10
841Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WVC7A0A087WVC7_HUMAN
Neuroblastoma breakpoint family mem...
NBPF10
1,239Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087X002A0A087X002_HUMAN
Neuroblastoma breakpoint family mem...
NBPF10
750Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AC239799 Genomic DNA No translation available.

NCBI Reference Sequences

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RefSeqi
NP_001289300.1, NM_001302371.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

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Ensembli
ENST00000583866; ENSP00000463957; ENSG00000271425

Database of genes from NCBI RefSeq genomes

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GeneIDi
100132406

UCSC genome browser

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UCSCi
uc057kcv.1, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC239799 Genomic DNA No translation available.
RefSeqiNP_001289300.1, NM_001302371.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9606.ENSP00000463957

Proteomic databases

PeptideAtlasiA0A075B762

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
75607, 15 antibodies

The DNASU plasmid repository

More...
DNASUi
100132406

Genome annotation databases

EnsembliENST00000583866; ENSP00000463957; ENSG00000271425
GeneIDi100132406
UCSCiuc057kcv.1, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
100132406
HGNCiHGNC:31992, NBPF10
OpenTargetsiENSG00000271425
VEuPathDBiHostDB:ENSG00000271425.6

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502RU1I, Eukaryota
GeneTreeiENSGT00420000029746
HOGENOMiCLU_224329_0_0_1
OrthoDBi372685at2759

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
100132406, 31 hits in 148 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
NBPF10, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
100132406

Gene expression databases

BgeeiENSG00000271425, Expressed in sural nerve and 115 other tissues
ExpressionAtlasiA0A075B762, baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR010630, Olduvai_dom
PfamiView protein in Pfam
PF06758, Olduvai, 42 hits
SMARTiView protein in SMART
SM01148, DUF1220, 42 hits
PROSITEiView protein in PROSITE
PS51316, NBPF, 42 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A075B762_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A075B762
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2014
Last sequence update: May 27, 2015
Last modified: April 7, 2021
This is version 43 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
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