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UniProtKB - A0A075B6P6 (A0A075B6P6_HUMAN)
Protein
Submitted name:
Potassium voltage-gated channel subfamily G member 1
Gene
KCNG1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- voltage-gated potassium channel activity Source: InterPro
GO - Biological processi
- protein homooligomerization Source: InterPro
- regulation of ion transmembrane transport Source: UniProtKB-KW
Keywordsi
Molecular function | Ion channel, Voltage-gated channelARBA annotation |
Biological process | Ion transport, Transport |
Names & Taxonomyi
Protein namesi | Submitted name: Potassium voltage-gated channel subfamily G member 1 |
Gene namesi | Name:KCNG1 |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:6248, KCNG1 |
VEuPathDBi | HostDB:ENSG00000026559 |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Plasma Membrane
- voltage-gated potassium channel complex Source: InterPro
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSG00000026559, Expressed in left uterine tube and 173 other tissues |
ExpressionAtlasi | A0A075B6P6, baseline and differential |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 63 – 172 | BTBInterPro annotationAdd BLAST | 110 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 184 – 204 | DisorderedSequence analysisAdd BLAST | 21 |
Keywords - Domaini
Transmembrane, Transmembrane helixARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000159686 |
OMAi | GQLKFCT |
Family and domain databases
Gene3Di | 1.20.120.350, 1 hit 3.30.710.10, 1 hit |
InterProi | View protein in InterPro IPR000210, BTB/POZ_dom IPR003969, K_chnl_volt-dep_Kv6 IPR011333, SKP1/BTB/POZ_sf IPR003131, T1-type_BTB IPR028325, VG_K_chnl IPR027359, Volt_channel_dom_sf |
PANTHERi | PTHR11537, PTHR11537, 1 hit |
Pfami | View protein in Pfam PF02214, BTB_2, 1 hit |
PRINTSi | PR01492, KV6CHANNEL |
SMARTi | View protein in SMART SM00225, BTB, 1 hit |
SUPFAMi | SSF54695, SSF54695, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
A0A075B6P6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTLLPGDNSD YDYSALSCTS DASFHPAFLP QRQAIKGAFY RRAQRLRPQD
60 70 80 90 100
EPRQGCQPED RRRRIIINVG GIKYSLPWTT LDEFPLTRLG QLKACTNFDD
110 120 130 140 150
ILNVCDDYDV TCNEFFFDRN PGAFGTILTF LRAGKLRLLR EMCALSFQEE
160 170 180 190 200
LLYWGIAEDH LDGCCKRRYL QKIEEFAEMV EREEEDDALD SEGRDSEGPA
210 220 230 240 250
EGEGRLGRCM RRLRDMVERP HSGLPGKVFA CLSVLFVTVT AVNLSVSTLP
SLREEEEQ
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9UIX4 | KCNG1_HUMAN | Potassium voltage-gated channel sub... | KCNG1 | 513 | Annotation score: | ||
A2A2I8 | A2A2I8_HUMAN | Potassium voltage-gated channel sub... | KCNG1 | 180 | Annotation score: | ||
Q5JXL4 | Q5JXL4_HUMAN | Potassium voltage-gated channel sub... | KCNG1 | 96 | Annotation score: | ||
A2A2I9 | A2A2I9_HUMAN | Potassium voltage-gated channel sub... | KCNG1 | 48 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 258 | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL050404 Genomic DNA No translation available. AL121785 Genomic DNA No translation available. KF456938 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000439216.5; ENSP00000394075.1; ENSG00000026559.14 |
UCSCi | uc061xtb.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL050404 Genomic DNA No translation available. AL121785 Genomic DNA No translation available. KF456938 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
Antibodypediai | 13829, 120 antibodies from 20 providers |
Genome annotation databases
Ensembli | ENST00000439216.5; ENSP00000394075.1; ENSG00000026559.14 |
UCSCi | uc061xtb.1, human |
Organism-specific databases
HGNCi | HGNC:6248, KCNG1 |
OpenTargetsi | ENSG00000026559 |
VEuPathDBi | HostDB:ENSG00000026559 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000159686 |
OMAi | GQLKFCT |
Miscellaneous databases
ChiTaRSi | KCNG1, human |
Gene expression databases
Bgeei | ENSG00000026559, Expressed in left uterine tube and 173 other tissues |
ExpressionAtlasi | A0A075B6P6, baseline and differential |
Family and domain databases
Gene3Di | 1.20.120.350, 1 hit 3.30.710.10, 1 hit |
InterProi | View protein in InterPro IPR000210, BTB/POZ_dom IPR003969, K_chnl_volt-dep_Kv6 IPR011333, SKP1/BTB/POZ_sf IPR003131, T1-type_BTB IPR028325, VG_K_chnl IPR027359, Volt_channel_dom_sf |
PANTHERi | PTHR11537, PTHR11537, 1 hit |
Pfami | View protein in Pfam PF02214, BTB_2, 1 hit |
PRINTSi | PR01492, KV6CHANNEL |
SMARTi | View protein in SMART SM00225, BTB, 1 hit |
SUPFAMi | SSF54695, SSF54695, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A075B6P6_HUMAN | |
Accessioni | A0A075B6P6Primary (citable) accession number: A0A075B6P6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 1, 2014 |
Last sequence update: | October 1, 2014 | |
Last modified: | May 25, 2022 | |
This is version 43 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |