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Protein
Submitted name:

Filamin A interacting protein 1, isoform CRA_c

Gene

FILIP1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Filamin A interacting protein 1, isoform CRA_cImported
Submitted name:
Filamin-A-interacting protein 1Imported
Gene namesi
Name:FILIP1Imported
ORF Names:hCG_17988Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000118407.14
HGNCiHGNC:21015 FILIP1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000118407

Expressioni

Gene expression databases

BgeeiENSG00000118407 Expressed in 176 organ(s), highest expression level in quadriceps femoris
ExpressionAtlasiA0A075B6G6 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 156CortBP2InterPro annotationAdd BLAST156

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili98 – 144Sequence analysisAdd BLAST47
Coiled coili162 – 196Sequence analysisAdd BLAST35
Coiled coili215 – 349Sequence analysisAdd BLAST135
Coiled coili357 – 391Sequence analysisAdd BLAST35
Coiled coili413 – 440Sequence analysisAdd BLAST28
Coiled coili445 – 486Sequence analysisAdd BLAST42
Coiled coili530 – 588Sequence analysisAdd BLAST59
Coiled coili611 – 676Sequence analysisAdd BLAST66

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IFP9 Eukaryota
ENOG410ZUI9 LUCA
GeneTreeiENSGT00930000150884

Family and domain databases

InterProiView protein in InterPro
IPR019131 Cortactin-binding_p2_N
PfamiView protein in Pfam
PF09727 CortBP2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A075B6G6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLKTEKTKPE VLEAHYGSAE PEKVLRVLHR DAILAQEKSI GEDVYEKPIS
60 70 80 90 100
ELDRLEEKQK ETYRRMLEQL LLAEKCHRRT VYELENEKHK HTDYMNKSDD
110 120 130 140 150
FTNLLEQERE RLKKLLEQEK AYQARKEKEN AKRLNKLRDE LVKLKSFALM
160 170 180 190 200
LVDERQMHIE QLGLQSQKVQ DLTQKLREEE EKLKAITSKS KEDRQKLLKL
210 220 230 240 250
EVDFEHKASR FSQEHEEMNA KLANQESHNR QLRLKLVGLT QRIEELEETN
260 270 280 290 300
KNLQKAEEEL QELRDKIAKG ECGNSSLMAE VENLRKRVLE MEGKDEEITK
310 320 330 340 350
TESQCRELRK KLQEEEHHSK ELRLEVEKLQ KRMSELEKLE EAFSKSKSEC
360 370 380 390 400
TQLHLNLEKE KNLTKDLLNE LEVVKSRVKE LECSESRLEK AELSLKDDLT
410 420 430 440 450
KLKSFTVMLV DERKNMMEKI KQEERKVDGL NKNFKVEQGK VMDVTEKLIE
460 470 480 490 500
ESKKLLKLKS EMEEKVYNLT RERDELIGKL KSEEEKSSEL SCSVDLLKKR
510 520 530 540 550
LDGIEEVERE ITRGRSRKGS ELTCPEDNKI KELTLEIERL KKRLQQLEVV
560 570 580 590 600
EGDLMKTEDE YDQLEQKFRT EQDKANFLSQ QLEEIKHQIA KNKAIEKGEV
610 620 630 640 650
VSQEAELRHR FRLEEAKSRD LKAEVQALKE KIHELMNKED QLSQLQVDYS
660 670 680 690 700
VLQQRFMEEE NKNKNMGQEV LNLTKELELS KRYSRALRPS VNGRRMVDVP
710 720 730 740 750
VTSTGVQTDA VSGEAAEEET PAVFIRKSFQ EENHIMSNLR QVGLKKPVER
760 770 780 790 800
SSVLDRYPPA ANELTMRKSW IPWMRKRENG PSITQEKGPR TNSSPGHPGE
810 820 830 840 850
VVLSPKQGQP LHIRVTPDHE NSTATLEITS PTSEEFFSST TVIPTLGNQK
860 870 880 890 900
PRITIIPSPN VMPQKQKSGD TTLGPERAMS PVTITTFSRE KTPESGRGAF
910 920 930 940 950
ADRPTSPIQI MTVSTSAAPA EIAVSPESQE MPMGRTILKV TPEKQTVPTP
960 970 980 990 1000
VRKYNSNANI ITTEDNKIHI HLGSQFKRSP GTSGEGVSPV ITVRPVNVTA
1010 1020 1030 1040 1050
EKEVSTGTVL RSPRNHLSSR PGASKVTSTI TITPVTTSSA RGTQSVSGQD
1060 1070 1080 1090 1100
GSSQRPTPTR IPMSKGMKAG KPVVAAPGAG NLTKFEPRAE TQSMKIELKK
1110
SAASSTTSLG GGKG
Length:1,114
Mass (Da):127,206
Last modified:October 1, 2014 - v1
Checksum:i6295577F920BF0B8
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q7Z7B0FLIP1_HUMAN
Filamin-A-interacting protein 1
FILIP1 KIAA1275
1,213Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL080250 Genomic DNA No translation available.
AL356057 Genomic DNA No translation available.
AL445465 Genomic DNA No translation available.
AL589649 Genomic DNA No translation available.
KF458209 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW48739.1
UniGeneiHs.201488
Hs.696158

Genome annotation databases

EnsembliENST00000370020; ENSP00000359037; ENSG00000118407
UCSCiuc003phz.4 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL080250 Genomic DNA No translation available.
AL356057 Genomic DNA No translation available.
AL445465 Genomic DNA No translation available.
AL589649 Genomic DNA No translation available.
KF458209 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW48739.1
UniGeneiHs.201488
Hs.696158

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000370020; ENSP00000359037; ENSG00000118407
UCSCiuc003phz.4 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000118407.14
HGNCiHGNC:21015 FILIP1
OpenTargetsiENSG00000118407
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IFP9 Eukaryota
ENOG410ZUI9 LUCA
GeneTreeiENSGT00930000150884

Miscellaneous databases

ChiTaRSiFILIP1 human

Gene expression databases

BgeeiENSG00000118407 Expressed in 176 organ(s), highest expression level in quadriceps femoris
ExpressionAtlasiA0A075B6G6 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR019131 Cortactin-binding_p2_N
PfamiView protein in Pfam
PF09727 CortBP2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A075B6G6_HUMAN
AccessioniPrimary (citable) accession number: A0A075B6G6
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2014
Last sequence update: October 1, 2014
Last modified: November 7, 2018
This is version 30 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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