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UniProtKB - A0A074ZYC6 (A0A074ZYC6_9TREM)

Entry version 21 (10 Feb 2021)
Sequence version 1 (01 Oct 2014)
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Protein

DUF4549 domain-containing protein

Gene

T265_02675

Organism
Opisthorchis viverrini
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DUF4549 domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:T265_02675Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOpisthorchis viverriniImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6198 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Spiralia › Lophotrochozoa › Platyhelminthes › Trematoda › Digenea › Opisthorchiida › Opisthorchiata › Opisthorchiidae › Opisthorchis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000054324 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini9 – 139DUF4549InterPro annotationAdd BLAST131

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni268 – 289DisorderedSequence analysisAdd BLAST22
Regioni312 – 373DisorderedSequence analysisAdd BLAST62
Regioni1734 – 1809DisorderedSequence analysisAdd BLAST76

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili2081 – 2101Sequence analysisAdd BLAST21
Coiled coili2114 – 2141Sequence analysisAdd BLAST28
Coiled coili2180 – 2200Sequence analysisAdd BLAST21
Coiled coili2283 – 2328Sequence analysisAdd BLAST46
Coiled coili2368 – 2392Sequence analysisAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi269 – 283PolarSequence analysisAdd BLAST15
Compositional biasi312 – 335PolarSequence analysisAdd BLAST24
Compositional biasi1746 – 1809PolarSequence analysisAdd BLAST64

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Database of Orthologous Groups

More...OrthoDBi		54096at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR040401, CCDC162
IPR029376, DUF4549

The PANTHER Classification System

More...PANTHERi		PTHR33331, PTHR33331, 3 hits

Pfam protein domain database

More...Pfami		View protein in Pfam
PF15082, DUF4549, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A074ZYC6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDEDEDVLKT QEDGLRSDIL ELRAQIEENE LIHGIPSKGM SSVYIPKDPD 
        60         70         80         90        100
YFRRERKLIL QRTLQVLEPK PITLQAELMM QELDACSQRE FTEKTLPILL 
       110        120        130        140        150
HQYFIDRIHQ IVLLKHGYLL RWKRYCSSTA AVETIQSEYL NRLEYLTNEY 
       160        170        180        190        200
LDASSRAHRL ASTREGILAN SDNGVEDVTV EDYQIYLRYH LSQLQSLSYA 
       210        220        230        240        250
NQLLNKQYPY ILCEDVTNVA PRGGSEAGGT EAATVNLTKT QGAVEREMSA 
       260        270        280        290        300
HSMSADEGEA LIAEETETLR SGQRASSEKG ESGVPPSQPV EAGVILDELK 
       310        320        330        340        350
ALEQAHAVNE SMFDETNTAT TARSLPPSTK KKSFQRKSLT NVEDSDDPLQ 
       360        370        380        390        400
GRGSEIASAP HPQSHFRFSE QAPQPPAMMH AAVVGANAPL QPTKANLDLA 
       410        420        430        440        450
SSGGGIVTND KVAAPPLHSN DLETLRPHLV YFCHAYGIQM NIQAIRSSAD 
       460        470        480        490        500
EMELFAVINR KFRQIFSRQE EMLTFKTYDS AKSASERWGL DSWVRAVRKP 
       510        520        530        540        550
SNWLPYVKLR PRRHEYLVKL TMELRSGTVV DDLLKASANF LKMKSPEKVQ 
       560        570        580        590        600
DSLRHHAMLV QHPPIVHSAS VVSHRQGQST AEIFKKIYNN SDVFGKASAD 
       610        620        630        640        650
TDEPGKRQDD YDFTQAMQML GLDDATNAKD DPSSVQGAYL SYLHLRHLKL 
       660        670        680        690        700
RDVMRTCISV LNYFRSIERT LTINDQGLSM NSRGGVERTS PPNHRVGTEA 
       710        720        730        740        750
QGHKGGGNTI DGHGYLFNSP QEFKIKETEF MQFAEVDNHD DFYFHEEGRI 
       760        770        780        790        800
HVRDQVGFWI VYDAALEDFN KLEQDLLLLA TAFIQRDRQS RMSSNTKKKG 
       810        820        830        840        850
VNQEAQSSDL DIARYAHRDV DRFGVLYDIW INECAFQQAK QKLMDVYMEV 
       860        870        880        890        900
YGHIISRDSR RRLAQIMTNL MYQRPRLDLN ESYFVLAYRY ECAILRQRTE 
       910        920        930        940        950
IMRCILNHQI LNQREYLKKI HVEKPEFGLP PPLLERFPIA VHSDETLLTP 
       960        970        980        990       1000
VYLLEFHPSL SCAPSLAAAM DQSVQQLYEL FTPNHPMQEI VLEKRFYDFL 
      1010       1020       1030       1040       1050
RYEVETLKPL GGSYTAQLQR DLFSSYFVED AIQMCELSNQ HLAAIQNRNS 
      1060       1070       1080       1090       1100
RGDKKTRQMY LLNELGRLLD LVTLRHRLID CMWECEVLSK IYLTVAHEMG 
      1110       1120       1130       1140       1150
FDDFHLFIRP LQFEAAKYKE GADDLRPPIY ITAVQDDDSM LDKFLPSALP 
      1160       1170       1180       1190       1200
LAIHELDETH VGKFSFRGKV TIMEMLETRG VENMLTILKV QTAHKNALTA 
      1210       1220       1230       1240       1250
SVMLAYNARP SFYTMHAPKT KTGILRPSNT GANLISYTGL SGTQVGPTPL 
      1260       1270       1280       1290       1300
ALERSKHQLN ADYHPEAFFS IQLEKSPSRD RTQNAFIKRT QGGGIASSKS 
      1310       1320       1330       1340       1350
SVESEKMKRE FISQFCMDFG QRTQHISLRA QIISTYSSIL TILEKVPTVT 
      1360       1370       1380       1390       1400
EDFFVIGYAF EKKNPEDDLD VQVTDPRTLR TRPRRVLSTD GTKLYNFWFI 
      1410       1420       1430       1440       1450
PHFIEVLFIF RHLDDLSCTK ALQRMARLAC VLHDILHYLI AYARLGISSA 
      1460       1470       1480       1490       1500
KITPEQRQQV IAGSQKHGGQ QWRTATRGAL PTAAEVAANI AGTTSAETFV 
      1510       1520       1530       1540       1550
AQLSSAGTIP SMNMALSSPA LSVTPLDLSV HGRSLVVDQI IATELREIQY 
      1560       1570       1580       1590       1600
QINRLPDPTD PEQVIQMLDL RRDVMFLQFD VCMRTILRET FLAAGNVEAY 
      1610       1620       1630       1640       1650
KEVVENSHFP LSELSDVQRP CLNAIEMNVP EPLEARDDQA KALFPWRSLM 
      1660       1670       1680       1690       1700
NRCGPFLLFC FGPSTIEYNI HLCMAGLKPV DRPTVHGELL AMNLCLEDVL 
      1710       1720       1730       1740       1750
DVGDIPEAKA GEPMPIQQAE NMHCMLGKRT RDRRREIPPP NAASPTGTGG 
      1760       1770       1780       1790       1800
PASTPGSVAG TTNPANATGT SINTMNITHS SETQGQKSST HGGAGGTGPL 
      1810       1820       1830       1840       1850
TTTPDKTPKL STLDSPVAAY TLLKKFLILW KRVELLKYAW GRRRLGVESI 
      1860       1870       1880       1890       1900
NNPNLFKTFC SIYKREKLYP LIRSLAIQYR QPDMYALGPL DATDIIVMPK 
      1910       1920       1930       1940       1950
GIPEMVVRQR QLLKLIEAFE FYMIADLRKL LLRQTDLVIK ERNREEGNLP 
      1960       1970       1980       1990       2000
LELWKRPLLK LIEAFEFYMI ADLRKLLLRQ TDLVIKERNR EEGNLPLELW 
      2010       2020       2030       2040       2050
KRPAMKETLS VKRPGLADEF LVELMSHLEQ NARNDTYIIT KDKLNEVLQT 
      2060       2070       2080       2090       2100
VAISVMRTQR ESYENYSMYY ENLLKNQHSL LYAKEREIET LKETLRQNEL 
      2110       2120       2130       2140       2150
ETNVTVQFQM SEQAHNLLLE VTALRAKIAE LEDINLKTEA KVRNRVRREF 
      2160       2170       2180       2190       2200
SVAMRKLFGL SFEQKSRIDQ YRDHLHAITL QRIAEVREEA SAEMARIKER 
      2210       2220       2230       2240       2250
SGARASAEDE LAERNLRLSR EVNTLHQRNI GLQQMMSRLR VMAHWQQTTL 
      2260       2270       2280       2290       2300
RCAFEKQISG VEEQRNQSKS QVTRLGILSE QRVRMLNEEM SKLRDHLSNT 
      2310       2320       2330       2340       2350
EKHLNDMRKA LDKEMSDKVE KRHAAERKAA TDKQMAMVKQ MHIDQLMAEI 
      2360       2370       2380       2390       2400
AEKNATLEKM GSLLDASAKS KKQEADKSVR EVDLLRKQLR EERKLKKSAI 
      2410       2420       2430       2440       2450
HKVDDLMSQL YEFETAYSSG QNRPGVNLPT VAPKGEATAG GARKLSAEIQ 
      2460       2470       2480       2490       2500
RPYEDLVAKK SGPYTSKHYL RFRQETTRVP QLRERLAQQI LRNGSGQTHM 
      2510 
HFLRTHDYSE TE
Length:2,512
Mass (Da):286,286
Last modified:October 1, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9529B450EB589B4D
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
KL596652 Genomic DNA Translation: KER30997.1

NCBI Reference Sequences

More...RefSeqi		XP_009165241.1, XM_009166977.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...GeneIDi		20316863

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ovi:T265_02675

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KL596652 Genomic DNA Translation: KER30997.1
RefSeqiXP_009165241.1, XM_009166977.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

GeneIDi20316863
KEGGiovi:T265_02675

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		20316863

Phylogenomic databases

OrthoDBi54096at2759

Family and domain databases

InterProiView protein in InterPro
IPR040401, CCDC162
IPR029376, DUF4549
PANTHERiPTHR33331, PTHR33331, 3 hits
PfamiView protein in Pfam
PF15082, DUF4549, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A074ZYC6_9TREM
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A074ZYC6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2014
Last sequence update: October 1, 2014
Last modified: February 10, 2021
This is version 21 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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