Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 57 (12 Aug 2020)
Sequence version 1 (01 Oct 2014)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein
Submitted name:

LysR family transcriptional regulator

Gene

mvfR

Organism
Pseudomonas aeruginosa
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-bindingImported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
LysR family transcriptional regulatorImported
Submitted name:
Putative DNA-binding transcriptional regulatorImported
Submitted name:
Transcriptional regulator MvfRImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mvfRImported
ORF Names:C0044_07600Imported, CAZ10_32620Imported, CGU42_28365Imported, DZ962_02275Imported, ECC04_024075Imported, EQH76_05735Imported, F7O90_09680Imported, F7O98_20540Imported, FC629_22960Imported, FDK04_22240Imported, GNQ48_31375Imported, IPC116_06490Imported, IPC1323_15845Imported, IPC1481_05740Imported, IPC1509_24760Imported, IPC36_06970Imported, IPC584_05175Imported, IPC669_29335Imported, NCTC12934_01994Imported, NCTC12951_05833Imported, NCTC13437_06683Imported, PaeAG1_04753Imported, PAMH19_4335Imported, RW109_RW109_05180Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPseudomonas aeruginosaImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri287 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000043988 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000297623 Componenti: Unassembled WGS sequence
  • UP000421245 Componenti: Unassembled WGS sequence
  • UP000426765 Componenti: Unassembled WGS sequence
  • UP000297361 Componenti: Unassembled WGS sequence
  • UP000258262 Componenti: Unassembled WGS sequence
  • UP000194857 Componenti: Unassembled WGS sequence
  • UP000297560 Componenti: Unassembled WGS sequence
  • UP000233777 Componenti: Chromosome mainomosome
  • UP000247072 Componenti: Unassembled WGS sequence
  • UP000351144 Componenti: Chromosome
  • UP000278438 Componenti: Unassembled WGS sequence
  • UP000341211 Componenti: Unassembled WGS sequence
  • UP000354661 Componenti: Unassembled WGS sequence
  • UP000297232 Componenti: Unassembled WGS sequence
  • UP000408447 Componenti: Unassembled WGS sequence
  • UP000424265 Componenti: Chromosome
  • UP000433532 Componenti: Unassembled WGS sequence
  • UP000297494 Componenti: Unassembled WGS sequence
  • UP000297376 Componenti: Unassembled WGS sequence
  • UP000285404 Componenti: Unassembled WGS sequence
  • UP000287066 Componenti: Unassembled WGS sequence
  • UP000422128 Componenti: Chromosome
  • UP000216659 Componenti: Unassembled WGS sequence

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...
ChEMBLi
CHEMBL2424500

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
287.DR97_945

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini4 – 61HTH lysR-typeInterPro annotationAdd BLAST58

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the LysR transcriptional regulatory family.ARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG0583, Bacteria

Database of Orthologous Groups

More...
OrthoDBi
750230at2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005119, LysR_subst-bd
IPR000847, Tscrpt_reg_HTH_LysR
IPR036388, WH-like_DNA-bd_sf
IPR036390, WH_DNA-bd_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00126, HTH_1, 1 hit
PF03466, LysR_substrate, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46785, SSF46785, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50931, HTH_LYSR, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A072ZLE6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPIHNLNHVN MFLQVIASGS ISSAARILRK SHTAVSSAVS NLEIDLCVEL
60 70 80 90 100
VRRDGYKVEP TEQALRLIPY MRSLLNYQQL IGDIAFNLNK GPRNLRVLLD
110 120 130 140 150
TAIPPSFCDT VSSVLLDDFN MVSLIRTSPA DSLATIKQDN AEIDIAITID
160 170 180 190 200
EELKISRFNQ CVLGYTKAFV VAHPQHPLCN ASLHSIASLA NYRQISLGSR
210 220 230 240 250
SGQHSNLLRP VSDKVLFVEN FDDMLRLVEA GVGWGIAPHY FVEERLRNGT
260 270 280 290 300
LAVLSELYEP GGIDTKVYCY YNTALESERS FLRFLESARQ RLRELGRQRF
310 320 330
DDAPAWQPSI VETAQRRSGP KALAYRQRAA PE
Length:332
Mass (Da):37,214
Last modified:October 1, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i117430C3C1232D97
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CDAZ01000013 Genomic DNA Translation: CEI18352.1
VZIM01000017 Genomic DNA Translation: KAB0729943.1
VZIW01000045 Genomic DNA Translation: KAB0763763.1
WOAD01000062 Genomic DNA Translation: MUI39486.1
NFFZ01000027 Genomic DNA Translation: OTI55580.1
NMRQ01000050 Genomic DNA Translation: OZO15055.1
QHLU01000565 Genomic DNA Translation: PXC01794.1
CP045739 Genomic DNA Translation: QGH92936.1
CP039988 Genomic DNA Translation: QGP98501.1
CP039990 Genomic DNA Translation: QGQ05192.1
QVBL01000002 Genomic DNA Translation: RFJ78004.1
NSVB01000020 Genomic DNA Translation: RPY65013.1
SBJW01000002 Genomic DNA Translation: RWY31267.1
LT969520 Genomic DNA Translation: SOV31057.1
RWMJ01000012 Genomic DNA Translation: TEE18552.1
RWNG01000003 Genomic DNA Translation: TEF47389.1
RWOM01000006 Genomic DNA Translation: TEH34096.1
RWQO01000001 Genomic DNA Translation: TEK72377.1
RWTJ01000002 Genomic DNA Translation: TEO98637.1
RWUZ01000002 Genomic DNA Translation: TER57036.1
RHMD02000002 Genomic DNA Translation: TGB22368.1
CAADJQ010000024 Genomic DNA Translation: VFT42532.1
CAADJS010000003 Genomic DNA Translation: VFT64253.1
CABEEH010000179 Genomic DNA Translation: VTQ29122.1

NCBI Reference Sequences

More...
RefSeqi
WP_003108614.1, NZ_WYAF01000019.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
CEI18352; CEI18352; PAMH19_4335
CRP81402; CRP81402; PAERUG_P32_London_17_VIM_2_10_11_05492
CRR79249; CRR79249; PAERUG_E15_London_28_01_14_10887
KSH08405; KSH08405; AO964_20870

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|287.1479.peg.3025

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CDAZ01000013 Genomic DNA Translation: CEI18352.1
VZIM01000017 Genomic DNA Translation: KAB0729943.1
VZIW01000045 Genomic DNA Translation: KAB0763763.1
WOAD01000062 Genomic DNA Translation: MUI39486.1
NFFZ01000027 Genomic DNA Translation: OTI55580.1
NMRQ01000050 Genomic DNA Translation: OZO15055.1
QHLU01000565 Genomic DNA Translation: PXC01794.1
CP045739 Genomic DNA Translation: QGH92936.1
CP039988 Genomic DNA Translation: QGP98501.1
CP039990 Genomic DNA Translation: QGQ05192.1
QVBL01000002 Genomic DNA Translation: RFJ78004.1
NSVB01000020 Genomic DNA Translation: RPY65013.1
SBJW01000002 Genomic DNA Translation: RWY31267.1
LT969520 Genomic DNA Translation: SOV31057.1
RWMJ01000012 Genomic DNA Translation: TEE18552.1
RWNG01000003 Genomic DNA Translation: TEF47389.1
RWOM01000006 Genomic DNA Translation: TEH34096.1
RWQO01000001 Genomic DNA Translation: TEK72377.1
RWTJ01000002 Genomic DNA Translation: TEO98637.1
RWUZ01000002 Genomic DNA Translation: TER57036.1
RHMD02000002 Genomic DNA Translation: TGB22368.1
CAADJQ010000024 Genomic DNA Translation: VFT42532.1
CAADJS010000003 Genomic DNA Translation: VFT64253.1
CABEEH010000179 Genomic DNA Translation: VTQ29122.1
RefSeqiWP_003108614.1, NZ_WYAF01000019.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi287.DR97_945

Chemistry databases

ChEMBLiCHEMBL2424500

Genome annotation databases

EnsemblBacteriaiCEI18352; CEI18352; PAMH19_4335
CRP81402; CRP81402; PAERUG_P32_London_17_VIM_2_10_11_05492
CRR79249; CRR79249; PAERUG_E15_London_28_01_14_10887
KSH08405; KSH08405; AO964_20870
PATRICifig|287.1479.peg.3025

Phylogenomic databases

eggNOGiCOG0583, Bacteria
OrthoDBi750230at2

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR005119, LysR_subst-bd
IPR000847, Tscrpt_reg_HTH_LysR
IPR036388, WH-like_DNA-bd_sf
IPR036390, WH_DNA-bd_sf
PfamiView protein in Pfam
PF00126, HTH_1, 1 hit
PF03466, LysR_substrate, 1 hit
SUPFAMiSSF46785, SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS50931, HTH_LYSR, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A072ZLE6_PSEAI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A072ZLE6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2014
Last sequence update: October 1, 2014
Last modified: August 12, 2020
This is version 57 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again