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Entry version 17 (07 Oct 2020)
Sequence version 1 (01 Oct 2014)
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Protein
Submitted name:

Putative conserved plasma membrane protein

Gene
N/A
Organism
Panstrongylus megistus
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processrRNA processingARBA annotation, tRNA processingARBA annotation
LigandATP-bindingARBA annotation, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Putative conserved plasma membrane proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPanstrongylus megistusImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri65343 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraHemipteraHeteropteraPanheteropteraCimicomorphaReduviidaeTriatominaePanstrongylus

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei289 – 308HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane, NucleusARBA annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini107 – 201DUF1726InterPro annotationAdd BLAST95
Domaini279 – 475Helicase_RecDInterPro annotationAdd BLAST197
Domaini515 – 740N-acetyltransferaseInterPro annotationAdd BLAST226
Domaini748 – 964tRNA_bind_2InterPro annotationAdd BLAST217

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili919 – 946Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

HAMAP database of protein families

More...
HAMAPi
MF_03211, RNA_acetyltr_Nat10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000182, GNAT_dom
IPR007807, Helicase_dom
IPR033688, NAT10
IPR032672, TmcA/NAT10/Kre33
IPR013562, TmcA_N
IPR027992, tRNA_bind_dom

The PANTHER Classification System

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PANTHERi
PTHR10925, PTHR10925, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF08351, DUF1726, 1 hit
PF13718, GNAT_acetyltr_2, 1 hit
PF05127, Helicase_RecD, 1 hit
PF13725, tRNA_bind_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

A0A069DZP1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTRTKIDNRI RLLIENGIKC SHRTMFVVVG DKGRDQVMIL HHILSKAVVK
60 70 80 90 100
ARPSVLWCYK KELGFSSNKM KRMKHVQRKI KIGKININED DPFELFIAST
110 120 130 140 150
NIRYCYYSET QKILGQTFGV CVLQDFEAIT PNLLARTIET VEGGGLVILL
160 170 180 190 200
LRTLTSLKQL YDMTMDVHER YRTEAHTDVV GRFNERFLLS LSSCKRCLVV
210 220 230 240 250
DDQLKILPIS SHVFDIQSMP DNGIVNQSDE DLKKLQDTLR DTQPVSSLIN
260 270 280 290 300
CCKTLDQAKA VLKFIDAISE KSLKYTVSLT AARGRGKSAA LGIAVAGAIA
310 320 330 340 350
FGYSNIFVTS PSPDNLKTFF EFVFKGFDVL GYQEHLDYGL VQSTNVEHNK
360 370 380 390 400
ALIRVNVFKT NRQTIQYISP LDSNKLSHAE LLVIDEAAAI PLPYVKNMFG
410 420 430 440 450
PYLIFLSSTI NGYEGTGRSL SLKLLQELRK QSTGSNDASN TPSKRTLHEI
460 470 480 490 500
TLEESIRYKP GDAVEQWLTE LLCLDATNSE RLWSGVPSPS ECDLYYINRD
510 520 530 540 550
TLFCYHKASE AFLHKIMALY VSSHYKNSPN DLQLMSDAPA HHLFCLLGPV
560 570 580 590 600
DPKKTVLPEV LCVIQVCLEG QISKRSVNVS LSHGNKPTGD LIPWTMAHQF
610 620 630 640 650
QDDEFPTLSG LRIVRIATHP DYQSMGYGAR ALSLLNDYYS LKIPVLDDLK
660 670 680 690 700
TTTDQQRNVF SRNGEEDLYN EIIEPRSSLP PLLMKLGERA PEKLDYLGVS
710 720 730 740 750
YGLTLPLLRF WKKADFVPVY LRQTSNDLTG EHSCIMLKSL SENENASWLN
760 770 780 790 800
QYWLDFRRRF ISLLSYQFRV FPTSLALGVI FNKQEKDVSS GLKKEELDYH
810 820 830 840 850
ITKYDLKRLE LYCNNVADYH LIMDLLPSLA KLFFLDQLGH VKCTAIQLAL
860 870 880 890 900
LVGVGLQHKT VDEVSKELDL PLSQLLGLQI RLIKKIYHVI MNIVEDSVEQ
910 920 930 940 950
TLGFNQNSNI TLNTDNTPLQ DLNEELEKAD KKIRKKQKHE KNMLKEQYGS
960 970 980 990 1000
EFAIKGSEDQ WSEALSSGNS NILSIKSGKM FISESPSEHQ DYTMIPKKKT

KK
Length:1,002
Mass (Da):113,756
Last modified:October 1, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i885BF43D59CE264A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1002Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
GBGD01000300 mRNA Translation: JAC88589.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GBGD01000300 mRNA Translation: JAC88589.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

HAMAPiMF_03211, RNA_acetyltr_Nat10, 1 hit
InterProiView protein in InterPro
IPR000182, GNAT_dom
IPR007807, Helicase_dom
IPR033688, NAT10
IPR032672, TmcA/NAT10/Kre33
IPR013562, TmcA_N
IPR027992, tRNA_bind_dom
PANTHERiPTHR10925, PTHR10925, 1 hit
PfamiView protein in Pfam
PF08351, DUF1726, 1 hit
PF13718, GNAT_acetyltr_2, 1 hit
PF05127, Helicase_RecD, 1 hit
PF13725, tRNA_bind_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A069DZP1_9HEMI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A069DZP1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2014
Last sequence update: October 1, 2014
Last modified: October 7, 2020
This is version 17 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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