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Entry version 35 (05 Jun 2019)
Sequence version 1 (03 Sep 2014)
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Protein

Piezo-type mechanosensitive ion channel component

Gene

pezo-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionIon channelUniRule annotation
Biological processIon transport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Piezo-type mechanosensitive ion channel componentUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:pezo-1Imported
ORF Names:C10C5.1Imported, CELE_C10C5.1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome IV

Organism-specific databases

WormBase

More...
WormBasei
C10C5.1f ; CE49932 ; WBGene00007505 ; pezo-1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei20 – 45HelicalUniRule annotationAdd BLAST26
Transmembranei57 – 81HelicalUniRule annotationAdd BLAST25
Transmembranei122 – 143HelicalUniRule annotationAdd BLAST22
Transmembranei175 – 199HelicalUniRule annotationAdd BLAST25
Transmembranei211 – 229HelicalUniRule annotationAdd BLAST19
Transmembranei241 – 264HelicalUniRule annotationAdd BLAST24
Transmembranei307 – 325HelicalUniRule annotationAdd BLAST19
Transmembranei414 – 433HelicalUniRule annotationAdd BLAST20
Transmembranei439 – 459HelicalUniRule annotationAdd BLAST21
Transmembranei466 – 487HelicalUniRule annotationAdd BLAST22
Transmembranei511 – 533HelicalUniRule annotationAdd BLAST23
Transmembranei589 – 610HelicalUniRule annotationAdd BLAST22
Transmembranei616 – 633HelicalUniRule annotationAdd BLAST18
Transmembranei645 – 665HelicalUniRule annotationAdd BLAST21
Transmembranei702 – 720HelicalUniRule annotationAdd BLAST19
Transmembranei781 – 802HelicalUniRule annotationAdd BLAST22
Transmembranei808 – 823HelicalUniRule annotationAdd BLAST16
Transmembranei830 – 849HelicalUniRule annotationAdd BLAST20
Transmembranei892 – 913HelicalUniRule annotationAdd BLAST22
Transmembranei1003 – 1024HelicalUniRule annotationAdd BLAST22
Transmembranei1065 – 1084HelicalUniRule annotationAdd BLAST20
Transmembranei1125 – 1144HelicalUniRule annotationAdd BLAST20
Transmembranei1150 – 1169HelicalUniRule annotationAdd BLAST20
Transmembranei1190 – 1212HelicalUniRule annotationAdd BLAST23
Transmembranei1579 – 1603HelicalUniRule annotationAdd BLAST25
Transmembranei1615 – 1638HelicalUniRule annotationAdd BLAST24
Transmembranei1669 – 1687HelicalUniRule annotationAdd BLAST19
Transmembranei1791 – 1810HelicalUniRule annotationAdd BLAST20
Transmembranei1830 – 1852HelicalUniRule annotationAdd BLAST23
Transmembranei1861 – 1879HelicalUniRule annotationAdd BLAST19
Transmembranei2003 – 2027HelicalUniRule annotationAdd BLAST25
Transmembranei2311 – 2332HelicalUniRule annotationAdd BLAST22

Keywords - Cellular componenti

Membrane

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00007505 Expressed in 4 organ(s), highest expression level in multi-cellular organism

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A0A061AE33 baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A0A061AE33

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1204 – 1419PIEZOInterPro annotationAdd BLAST216
Domaini1942 – 2395Piezo_RRas_bdgInterPro annotationAdd BLAST454

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni354 – 379DisorderedSequence analysisAdd BLAST26
Regioni728 – 758DisorderedSequence analysisAdd BLAST31
Regioni1423 – 1462DisorderedSequence analysisAdd BLAST40

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1308 – 1328Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi735 – 758PolarSequence analysisAdd BLAST24

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PIEZO (TC 1.A.75) family. [View classification]UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1893 Eukaryota
ENOG410YVF6 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000166986

Database of Orthologous Groups

More...
OrthoDBi
13738at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027272 Piezo
IPR031805 Piezo_dom
IPR031334 Piezo_RRas-bd_dom

The PANTHER Classification System

More...
PANTHERi
PTHR13167 PTHR13167, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15917 PIEZO, 1 hit
PF12166 Piezo_RRas_bdg, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 11 potential isoforms that are computationally mapped.Show allAlign All

A0A061AE33-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTVPPLLKSC VVKLLLPAAL LAAAIIRPSF LSIGYVLLAL VSAVLPPIRK
60 70 80 90 100
SLALPKLVGT FVIITFLFCL AVALGVGSYQ ISEQVVHKND RTYICNRSDT
110 120 130 140 150
TLFRSIGLVR FHPTGTFEST RAFLPEIIAT SAALLTIIIV MFLSHRDEQL
160 170 180 190 200
DVVGDVVTVR SESGREQRRQ RKLAAIMWSA IGNSLRRLTN FVLFLFTAYV
210 220 230 240 250
GIVKPSLSNS IYFLAFLFIS TWWSTYTPLR HGVYNQIKKF LIFYSALHFL
260 270 280 290 300
VLYTYQIPIV HHSWLPTGSF LPRLFGLTVL MDSSCPEWWK FPFVAPDFND
310 320 330 340 350
DDLIMKWPLY ANPIVVLVFF YLTVAQYKFT RNGSREYIDD NEYGSSVHEE
360 370 380 390 400
LLSNASSSAN DDEQGRARSR SPLRNGEEQG SIPLRKVTSQ VVDRNKLSNI
410 420 430 440 450
FNTPGDKESA ASKGMIAVMT FVIFHSYSIA LTAMMTWALL YHSIFGLILL
460 470 480 490 500
ILTCILWIFR DTRKSSFAMA PIILMYIEFL LILQYFLSMD IHAEIGDPAW
510 520 530 540 550
MNFVGIEWTT LPVHAVIILC VQTLLTLPVF LLLRLARREK FYESLSDYER
560 570 580 590 600
QRRINSYGTF GASKTGAGGV AVAKFQDPKS RKFAAFVEYL SNKVSVYFIF
610 620 630 640 650
VVSVVLLVVS TCFAPNFYNI LFFALWALNL IYLKFSFRLY RGLAYAFWLT
660 670 680 690 700
LTFYTSIVII ALYIYQFPGV SQWIIRNTSL SQEWLNAIGL VDFRAIGESG
710 720 730 740 750
ALFLQLLAPI ALFVVTMLQL KFFHGPWSRA TSPRRAENDP PTSTTEAAAV
760 770 780 790 800
ASTSGTQGRA HAAGDTLVKK LHKLANQTIE LLWRFFEVHI SKIVFVIIAI
810 820 830 840 850
FIANNINALY IPLVILLSLA ICLPSAADGI FSLFMCAYLF LVALSKMIYQ
860 870 880 890 900
LDIVPELSQI DRGVGADNCS HGNISMPEWF GLKKEVEGTE PIYMLFGVIV
910 920 930 940 950
SIIALAFQSI VIYRQRHYRA SLGLPESMRA KVFPDFHHSH FDRSLKNAIQ
960 970 980 990 1000
FLIDYGFYKF GLEITMIAIG IDIFNRMDAL AAIQCFWLVL FALNKRVFVR
1010 1020 1030 1040 1050
RIWVFYVIYM AILYPLQFFS YVGLPPDSCI EYPWSYWIPS YSDDARFNLS
1060 1070 1080 1090 1100
YLLNLSIYGV NWPSAYLIGD FFVLLLASCQ LAVFRREGED NDSIYNDGNF
1110 1120 1130 1140 1150
VIKPENPQYD FIDTKKSYVD YFKSFVFHYG HWITLMSTLA AGIAGTSLFA
1160 1170 1180 1190 1200
LGYIIFTLTM LWSGNNLYVM NSTLRSFEHT LKRWNALLGY TLFTITMKVC
1210 1220 1230 1240 1250
LQIFGCVFLS WFDQSGGWGK TLCIVRQLFS ITCVNNECHV LKELEDFSKA
1260 1270 1280 1290 1300
CAVETKEGNI GFDVIALSFL VFQIRIFHSW YFQHCMVEYR SEVILANRGA
1310 1320 1330 1340 1350
VLKNQLIEKE MKEQNEQQKA KFNDIRRRTE AIRERYQKQI ERGAAERDFE
1360 1370 1380 1390 1400
PVTYGHAKRA GDYYMFKYDP ENDDLVEPVD SFVPEVDPKA TAYDRLDPGQ
1410 1420 1430 1440 1450
IMYAATAHDL DLAKTVQQVK KGDTIKDPDS RALIAVSEPE ARKPGGTEET
1460 1470 1480 1490 1500
DGDEDEDNKD SKVESTAKFI QKMIASALDL CSVTLNKLCR EHRYVGFVLS
1510 1520 1530 1540 1550
KEKQKLKSGH SESLSNTSRK LTDIRSAVDL PSLQLVQSAN DVEKMETAVS
1560 1570 1580 1590 1600
VDWQQKSSAT RLLNAVVNCI GAHTDILCYF FAIMTQVMTG GLITLPLPLM
1610 1620 1630 1640 1650
SLFWGNLSNP RPSKFFWVTM ITYTECVIVI KFVCQFAFMP YNSITWRTEH
1660 1670 1680 1690 1700
QMDPMSLDKL FGVSQRDSFA LWDIVLLFSL FFHRYMLRKL GLWKDANLTD
1710 1720 1730 1740 1750
TFTLKEEPRS ASGSDTGSPK KIAQEPKVVV TQSDTLEGTS GGEIVIPSDP
1760 1770 1780 1790 1800
NAVSNMEELD CEPPIPEKQS GPIGRFIHQL FHPKFRYIRD LYPIMFGIDV
1810 1820 1830 1840 1850
ICFLIMTFGY SAFGEGGSGN VLDDVKASRI PVTLVVMLVG MTLAIIIDRA
1860 1870 1880 1890 1900
LYLRKSVVGK LIYQVLMIAF LHIWVFLVLP NMTRRSAISN HVAQALYVIK
1910 1920 1930 1940 1950
SCYFLVSAWQ IRNGYPELCI GNLLTHSYGM TNMIAFKVFM NIPFLFELRT
1960 1970 1980 1990 2000
AIDWTWTDTS MPLFDFFNME NFYAHIFNIK CARQFEAAYP APRGIPKGKL
2010 2020 2030 2040 2050
VKYMMGFPII IGVVIFIFSP LLLWSLLNQI GTISMPEKVT LRISIEGYPP
2060 2070 2080 2090 2100
LYEMEAQGSN HDNAELGMIK PDQLASLNQA LTDSYTTRDT NSILRSRMSV
2110 2120 2130 2140 2150
SYLKGYTYED ILIVRFRPES EIYWPISQDS RNAMIDKLSR NTSVNFEVSL
2160 2170 2180 2190 2200
EFTRPYDPNE NAALKHSKSW LVPISLDMTI RAKIQSALRG DPGHPILIPQ
2210 2220 2230 2240 2250
SIPAFIQVPN QGELTLPTSI GNTIINDGNP RINTTGMEKS DEARAWFDSL
2260 2270 2280 2290 2300
TLNLEQGKSQ NEKMWIATSE HPGDQNAKLW IKTANTTYSG RPYLQVVGFI
2310 2320 2330 2340 2350
DRAFPSFLAK VFKGGVIAVY LSVILVVGRG LVRGIFTTSP STVMFTELPN
2360 2370 2380 2390 2400
ADHLLKICLD IYLVREAKDF MLEQDLFAKL IFLFRSPATL IEWTRMSKKK

QE
Length:2,402
Mass (Da):272,788
Last modified:September 3, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA2260BA71D410CA6
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 11 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D0VWN8D0VWN8_CAEEL
Piezo-type mechanosensitive ion cha...
pezo-1 C10C5.1, CELE_C10C5.1
2,440Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C6KRJ3C6KRJ3_CAEEL
Piezo-type mechanosensitive ion cha...
pezo-1 C10C5.1, CELE_C10C5.1
2,400Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q17897Q17897_CAEEL
Piezo-type mechanosensitive ion cha...
pezo-1 C10C5.1, CELE_C10C5.1
2,438Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A061ACU2A0A061ACU2_CAEEL
Piezo-type mechanosensitive ion cha...
pezo-1 C10C5.1, CELE_C10C5.1
2,442Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H9G2S3H9G2S3_CAEEL
Piezo-type mechanosensitive ion cha...
pezo-1 C10C5.1, CELE_C10C5.1
2,440Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A061AJB7A0A061AJB7_CAEEL
Piezo-type mechanosensitive ion cha...
pezo-1 C10C5.1, CELE_C10C5.1
2,404Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H9G2S2H9G2S2_CAEEL
Piezo-type mechanosensitive ion cha...
pezo-1 C10C5.1, CELE_C10C5.1
2,402Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A061AL01A0A061AL01_CAEEL
Piezo-type mechanosensitive ion cha...
pezo-1 C10C5.1, CELE_C10C5.1
1,686Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
O01260O01260_CAEEL
Piezo-type mechanosensitive ion cha...
pezo-1 C10C5.1, CELE_C10C5.1
1,704Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B9WRT3B9WRT3_CAEEL
Piezo-type mechanosensitive ion cha...
pezo-1 C10C5.1, CELE_C10C5.1
1,730Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There is more potential isoformShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284604 Genomic DNA Translation: CDR32749.1

NCBI Reference Sequences

More...
RefSeqi
NP_001293979.1, NM_001307050.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
C10C5.1f; C10C5.1f; WBGene00007505

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
182492

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA Translation: CDR32749.1
RefSeqiNP_001293979.1, NM_001307050.1

3D structure databases

SMRiA0A061AE33
ModBaseiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC10C5.1f; C10C5.1f; WBGene00007505
GeneIDi182492

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
182492
WormBaseiC10C5.1f ; CE49932 ; WBGene00007505 ; pezo-1

Phylogenomic databases

eggNOGiKOG1893 Eukaryota
ENOG410YVF6 LUCA
GeneTreeiENSGT00940000166986
OrthoDBi13738at2759

Gene expression databases

BgeeiWBGene00007505 Expressed in 4 organ(s), highest expression level in multi-cellular organism
ExpressionAtlasiA0A061AE33 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR027272 Piezo
IPR031805 Piezo_dom
IPR031334 Piezo_RRas-bd_dom
PANTHERiPTHR13167 PTHR13167, 1 hit
PfamiView protein in Pfam
PF15917 PIEZO, 1 hit
PF12166 Piezo_RRas_bdg, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A061AE33_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A061AE33
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 3, 2014
Last sequence update: September 3, 2014
Last modified: June 5, 2019
This is version 35 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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