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Entry version 59 (17 Jun 2020)
Sequence version 1 (09 Jul 2014)
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Protein
Submitted name:

LuxR family transcriptional regulator

Gene

AYJ03_004735

Organism
Mycobacterium tuberculosis
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
LuxR family transcriptional regulatorImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:AYJ03_004735Imported, DSI38_03480Imported, E5M05_02115Imported, ERS007657_00038Imported, ERS007661_00975Imported, ERS007663_00548Imported, ERS007665_00382Imported, ERS007670_00971Imported, ERS007679_03008Imported, ERS007681_01928Imported, ERS007688_02460Imported, ERS007720_01064Imported, ERS007722_02992Imported, ERS013471_01722Imported, ERS024276_00704Imported, ERS027659_02136Imported, ERS027661_00078Imported, FRD82_00725Imported, GJE03_04740Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMycobacterium tuberculosisImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1773 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000321489 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000256245 Componenti: Unassembled WGS sequence
  • UP000045842 Componenti: Unassembled WGS sequence
  • UP000049989 Componenti: Unassembled WGS sequence
  • UP000041288 Componenti: Unassembled WGS sequence
  • UP000039217 Componenti: Unassembled WGS sequence
  • UP000043293 Componenti: Unassembled WGS sequence
  • UP000049023 Componenti: Unassembled WGS sequence
  • UP000046947 Componenti: Unassembled WGS sequence
  • UP000075723 Componenti: Chromosome
  • UP000048289 Componenti: Unassembled WGS sequence
  • UP000046680 Componenti: Unassembled WGS sequence
  • UP000298175 Componenti: Unassembled WGS sequence
  • UP000046213 Componenti: Unassembled WGS sequence
  • UP000388593 Componenti: Chromosome
  • UP000045274 Componenti: Unassembled WGS sequence
  • UP000050164 Componenti: Unassembled WGS sequence
  • UP000040993 Componenti: Unassembled WGS sequence
  • UP000044938 Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027417 P-loop_NTPase

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A045KDI7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPSRATVQEF SDSYPFCHNG FRPIMMPKIV SVQHSTRRHL TSFVGRKAEL
60 70 80 90 100
NDVRRLLSDK RLVTLTGPDG MGKSRLALQI GAQIAHEFTY GRWDCDLATV
110 120 130 140 150
TDRDCVSISM LNALGLPVQP GLSAIDTLVG VINDARVLLV LDHCEHLLDA
160 170 180 190 200
CAAIIDSLLR SCPRLTILTT STEAIGLAGE LTWRVPPLSL TNDAIELFVD
210 220 230 240 250
RARRVRSDFA INADTAVTVG EICRRLDGVP LAIELAAART DTLSPVEILA
260 270 280 290 300
GLNDRFRLVA GAAGNAVRPE QTLCATVQWS HALLSGPERA LLHRLAVFAG
310 320 330 340 350
GFDLDGAQAV GANDEDFEGY QTLGRFAELV DKAFVVVENN RGRAGYRLLY
360 370 380 390
SVRQYALEKL SESGEADAVL ARYRKHLKQP NQVVRAGSGG VRY
Length:393
Mass (Da):42,873
Last modified:July 9, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5EF7BE41F4E51715
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CFOE01000222 Genomic DNA Translation: CFE39548.1
CFOH01000413 Genomic DNA Translation: CFE55605.1
CGCX01000006 Genomic DNA Translation: CFR64398.1
CNCN01000109 Genomic DNA Translation: CKN93356.1
CNFU01000007 Genomic DNA Translation: CKQ79834.1
CNFT01000475 Genomic DNA Translation: CKR75893.1
CQPW01000041 Genomic DNA Translation: CNU09169.1
CQPV01000051 Genomic DNA Translation: CNU12401.1
CQPL01000136 Genomic DNA Translation: CNU15751.1
CQQC01000230 Genomic DNA Translation: CNU64217.1
CQTT01000037 Genomic DNA Translation: CNY48128.1
CSAJ01000094 Genomic DNA Translation: COV85674.1
CSAD01000481 Genomic DNA Translation: COW05339.1
CSAM01000264 Genomic DNA Translation: COW56464.1
CP045962 Genomic DNA Translation: QGK78176.1
CP046529 Genomic DNA Translation: QGV20620.1
QSXJ01000283 Genomic DNA Translation: REM68893.1
SRLI01000003 Genomic DNA Translation: TGE07261.1
VOOQ01000012 Genomic DNA Translation: TXB95268.1

NCBI Reference Sequences

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RefSeqi
WP_003404660.1, NZ_WJSJ01000005.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
CFE39548; CFE39548; ERS007681_01928
CFE55605; CFE55605; ERS007688_02460
CFR64398; CFR64398; ERS007657_00038
CKN93356; CKN93356; ERS024276_00704
CKO25010; CKO25010; ERS024213_00130
CKQ79834; CKQ79834; ERS027661_00078
CKR17742; CKR17742; ERS027656_00745
CKR18597; CKR18597; ERS027653_00814
CKR49157; CKR49157; ERS027652_01553
CKR75893; CKR75893; ERS027659_02136
CKS07716; CKS07716; ERS027666_00491
CKS10864; CKS10864; ERS027654_02751
CKV36859; CKV36859; ERS031537_02608
CNU09169; CNU09169; ERS007665_00382
CNU12401; CNU12401; ERS007663_00548
CNU15751; CNU15751; ERS007670_00971
CNU64217; CNU64217; ERS007661_00975
CNY48128; CNY48128; ERS013471_01722
COV19511; COV19511; ERS007672_01267
COV85674; COV85674; ERS007720_01064
COW05339; COW05339; ERS007679_03008
COW56464; COW56464; ERS007722_02992
COW80324; COW80324; ERS007739_00106

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CFOE01000222 Genomic DNA Translation: CFE39548.1
CFOH01000413 Genomic DNA Translation: CFE55605.1
CGCX01000006 Genomic DNA Translation: CFR64398.1
CNCN01000109 Genomic DNA Translation: CKN93356.1
CNFU01000007 Genomic DNA Translation: CKQ79834.1
CNFT01000475 Genomic DNA Translation: CKR75893.1
CQPW01000041 Genomic DNA Translation: CNU09169.1
CQPV01000051 Genomic DNA Translation: CNU12401.1
CQPL01000136 Genomic DNA Translation: CNU15751.1
CQQC01000230 Genomic DNA Translation: CNU64217.1
CQTT01000037 Genomic DNA Translation: CNY48128.1
CSAJ01000094 Genomic DNA Translation: COV85674.1
CSAD01000481 Genomic DNA Translation: COW05339.1
CSAM01000264 Genomic DNA Translation: COW56464.1
CP045962 Genomic DNA Translation: QGK78176.1
CP046529 Genomic DNA Translation: QGV20620.1
QSXJ01000283 Genomic DNA Translation: REM68893.1
SRLI01000003 Genomic DNA Translation: TGE07261.1
VOOQ01000012 Genomic DNA Translation: TXB95268.1
RefSeqiWP_003404660.1, NZ_WJSJ01000005.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiCFE39548; CFE39548; ERS007681_01928
CFE55605; CFE55605; ERS007688_02460
CFR64398; CFR64398; ERS007657_00038
CKN93356; CKN93356; ERS024276_00704
CKO25010; CKO25010; ERS024213_00130
CKQ79834; CKQ79834; ERS027661_00078
CKR17742; CKR17742; ERS027656_00745
CKR18597; CKR18597; ERS027653_00814
CKR49157; CKR49157; ERS027652_01553
CKR75893; CKR75893; ERS027659_02136
CKS07716; CKS07716; ERS027666_00491
CKS10864; CKS10864; ERS027654_02751
CKV36859; CKV36859; ERS031537_02608
CNU09169; CNU09169; ERS007665_00382
CNU12401; CNU12401; ERS007663_00548
CNU15751; CNU15751; ERS007670_00971
CNU64217; CNU64217; ERS007661_00975
CNY48128; CNY48128; ERS013471_01722
COV19511; COV19511; ERS007672_01267
COV85674; COV85674; ERS007720_01064
COW05339; COW05339; ERS007679_03008
COW56464; COW56464; ERS007722_02992
COW80324; COW80324; ERS007739_00106

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
SUPFAMiSSF52540 SSF52540, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A045KDI7_MYCTX
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A045KDI7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: June 17, 2020
This is version 59 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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