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Entry version 61 (12 Aug 2020)
Sequence version 1 (09 Jul 2014)
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Protein
Submitted name:

HesB/YadR/YfhF family protein

Gene

DSI38_02555

Organism
Mycobacterium tuberculosis
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
HesB/YadR/YfhF family proteinImported
Submitted name:
Iron-sulfur cluster assembly accessory proteinImported
Submitted name:
Putative iron-sulfur cluster biosynthesis proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:DSI38_02555Imported, E5M52_11060Imported, ERS007663_03674Imported, ERS007665_02191Imported, ERS007679_03129Imported, ERS007681_02784Imported, ERS007688_03954Imported, ERS007703_04686Imported, ERS007722_03922Imported, ERS007741_03410Imported, ERS013471_02970Imported, ERS023446_01532Imported, ERS027646_03888Imported, ERS027659_03015Imported, ERS027661_02786Imported, ERS075361_02968Imported, ERS094182_00917Imported, F6W99_00800Imported, F9908_00760Imported, FRD82_16110Imported, SAMEA2683035_01296Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMycobacterium tuberculosisImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1773 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000321489 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000048948 Componenti: Unassembled WGS sequence
  • UP000256245 Componenti: Unassembled WGS sequence
  • UP000045842 Componenti: Unassembled WGS sequence
  • UP000297584 Componenti: Unassembled WGS sequence
  • UP000431688 Componenti: Unassembled WGS sequence
  • UP000043293 Componenti: Unassembled WGS sequence
  • UP000049023 Componenti: Unassembled WGS sequence
  • UP000048600 Componenti: Unassembled WGS sequence
  • UP000047893 Componenti: Unassembled WGS sequence
  • UP000039953 Componenti: Unassembled WGS sequence
  • UP000046947 Componenti: Unassembled WGS sequence
  • UP000182946 Componenti: Unassembled WGS sequence
  • UP000048289 Componenti: Unassembled WGS sequence
  • UP000038802 Componenti: Unassembled WGS sequence
  • UP000042440 Componenti: Unassembled WGS sequence
  • UP000326088 Componenti: Chromosome
  • UP000046213 Componenti: Unassembled WGS sequence
  • UP000045274 Componenti: Unassembled WGS sequence
  • UP000050164 Componenti: Unassembled WGS sequence
  • UP000040993 Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini15 – 115Fe-S_biosynInterPro annotationAdd BLAST101

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.300.12, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000361, FeS_biogenesis
IPR016092, FeS_cluster_insertion
IPR017870, FeS_cluster_insertion_CS
IPR035903, HesB-like_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01521, Fe-S_biosyn, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF89360, SSF89360, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00049, TIGR00049, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01152, HESB, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A045JN01-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTVQNEPSAK THGVILTEAA AAKAKSLLDQ EGRDDLALRI AVQPGGCAGL
60 70 80 90 100
RYNLFFDDRT LDGDQTAEFG GVRLIVDRMS APYVEGASID FVDTIEKQGF
110
TIDNPNATGS CACGDSFN
Length:118
Mass (Da):12,544
Last modified:July 9, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i73B082E2B23F9993
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CFOE01000403 Genomic DNA Translation: CFE41159.1
CFOH01000992 Genomic DNA Translation: CFE76127.1
CNFU01000634 Genomic DNA Translation: CKS23534.1
CNFT01000805 Genomic DNA Translation: CKS37345.1
CNGE01001013 Genomic DNA Translation: CKT61417.1
CQAC01000024 Genomic DNA Translation: CNH00349.1
CQGE01000025 Genomic DNA Translation: CNM88909.1
CQPW01000435 Genomic DNA Translation: CNV11380.1
CQPV01000805 Genomic DNA Translation: CNV57451.1
CQTT01000099 Genomic DNA Translation: CNY88285.1
CSAD01000519 Genomic DNA Translation: COW10253.1
CHKL01000511 Genomic DNA Translation: COW91304.1
CSAM01000472 Genomic DNA Translation: COX00854.1
CSAE01000893 Genomic DNA Translation: COX05362.1
CVKR01000005 Genomic DNA Translation: CRF25493.1
WFKV01000001 Genomic DNA Translation: KAB7807588.1
CP044345 Genomic DNA Translation: QEX90025.1
QSXJ01000203 Genomic DNA Translation: REM69089.1
FPTZ01000006 Genomic DNA Translation: SGH49836.1
SRLJ01000021 Genomic DNA Translation: TGD76495.1
VOOQ01000541 Genomic DNA Translation: TXB92382.1

NCBI Reference Sequences

More...
RefSeqi
WP_003411418.1, NZ_WUJD01000033.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AMC46630; AMC46630; RN05_2354
CFE41159; CFE41159; ERS007681_02784
CFE76127; CFE76127; ERS007688_03954
CKP35414; CKP35414; ERS024213_01915
CKR15273; CKR15273; ERS027654_00745
CKR35194; CKR35194; ERS027644_01038
CKR59945; CKR59945; ERS027652_01828
CKS23534; CKS23534; ERS027661_02786
CKS37345; CKS37345; ERS027659_03015
CKS38161; CKS38161; ERS027656_02926
CKS85671; CKS85671; ERS027666_01704
CKT61417; CKT61417; ERS027646_03888
CKV56671; CKV56671; ERS031537_02976
CNG51684; CNG51684; ERS124361_01139
CNM88909; CNM88909; ERS023446_01532
CNV11380; CNV11380; ERS007665_02191
CNV57451; CNV57451; ERS007663_03674
CNY88285; CNY88285; ERS013471_02970
COW10253; COW10253; ERS007679_03129
COW16256; COW16256; ERS007672_03159
COW63803; COW63803; ERS007737_00154
COW91304; COW91304; ERS007741_03410
COX00854; COX00854; ERS007722_03922
COX05362; COX05362; ERS007703_04686
CRH09858; CRH09858; BN1303_00372
CRH10957; CRH10957; BN1213_01026

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
23491601

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1773.206.peg.1697

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CFOE01000403 Genomic DNA Translation: CFE41159.1
CFOH01000992 Genomic DNA Translation: CFE76127.1
CNFU01000634 Genomic DNA Translation: CKS23534.1
CNFT01000805 Genomic DNA Translation: CKS37345.1
CNGE01001013 Genomic DNA Translation: CKT61417.1
CQAC01000024 Genomic DNA Translation: CNH00349.1
CQGE01000025 Genomic DNA Translation: CNM88909.1
CQPW01000435 Genomic DNA Translation: CNV11380.1
CQPV01000805 Genomic DNA Translation: CNV57451.1
CQTT01000099 Genomic DNA Translation: CNY88285.1
CSAD01000519 Genomic DNA Translation: COW10253.1
CHKL01000511 Genomic DNA Translation: COW91304.1
CSAM01000472 Genomic DNA Translation: COX00854.1
CSAE01000893 Genomic DNA Translation: COX05362.1
CVKR01000005 Genomic DNA Translation: CRF25493.1
WFKV01000001 Genomic DNA Translation: KAB7807588.1
CP044345 Genomic DNA Translation: QEX90025.1
QSXJ01000203 Genomic DNA Translation: REM69089.1
FPTZ01000006 Genomic DNA Translation: SGH49836.1
SRLJ01000021 Genomic DNA Translation: TGD76495.1
VOOQ01000541 Genomic DNA Translation: TXB92382.1
RefSeqiWP_003411418.1, NZ_WUJD01000033.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiAMC46630; AMC46630; RN05_2354
CFE41159; CFE41159; ERS007681_02784
CFE76127; CFE76127; ERS007688_03954
CKP35414; CKP35414; ERS024213_01915
CKR15273; CKR15273; ERS027654_00745
CKR35194; CKR35194; ERS027644_01038
CKR59945; CKR59945; ERS027652_01828
CKS23534; CKS23534; ERS027661_02786
CKS37345; CKS37345; ERS027659_03015
CKS38161; CKS38161; ERS027656_02926
CKS85671; CKS85671; ERS027666_01704
CKT61417; CKT61417; ERS027646_03888
CKV56671; CKV56671; ERS031537_02976
CNG51684; CNG51684; ERS124361_01139
CNM88909; CNM88909; ERS023446_01532
CNV11380; CNV11380; ERS007665_02191
CNV57451; CNV57451; ERS007663_03674
CNY88285; CNY88285; ERS013471_02970
COW10253; COW10253; ERS007679_03129
COW16256; COW16256; ERS007672_03159
COW63803; COW63803; ERS007737_00154
COW91304; COW91304; ERS007741_03410
COX00854; COX00854; ERS007722_03922
COX05362; COX05362; ERS007703_04686
CRH09858; CRH09858; BN1303_00372
CRH10957; CRH10957; BN1213_01026
GeneIDi23491601
PATRICifig|1773.206.peg.1697

Family and domain databases

Gene3Di2.60.300.12, 1 hit
InterProiView protein in InterPro
IPR000361, FeS_biogenesis
IPR016092, FeS_cluster_insertion
IPR017870, FeS_cluster_insertion_CS
IPR035903, HesB-like_dom_sf
PfamiView protein in Pfam
PF01521, Fe-S_biosyn, 1 hit
SUPFAMiSSF89360, SSF89360, 1 hit
TIGRFAMsiTIGR00049, TIGR00049, 1 hit
PROSITEiView protein in PROSITE
PS01152, HESB, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A045JN01_MYCTX
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A045JN01
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: August 12, 2020
This is version 61 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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