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Entry version 62 (12 Aug 2020)
Sequence version 1 (09 Jul 2014)
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Protein

CRISPR system Cms endoribonuclease Csm3

Gene

CAB90_03150

Organism
Mycobacterium tuberculosis
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionEndonucleaseARBA annotation, Hydrolase, Nuclease, RNA-bindingARBA annotation
Biological processAntiviral defenseARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
CRISPR system Cms endoribonuclease Csm3ARBA annotation
Alternative name(s):
CRISPR type III A-associated RAMP protein Csm3ARBA annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:CAB90_03150Imported, DSI38_21485Imported, E5M52_17770Imported, ERS007657_02155Imported, ERS007663_02787Imported, ERS007670_00254Imported, ERS007681_01405Imported, ERS007688_01385Imported, ERS007703_00997Imported, ERS007720_02303Imported, ERS007722_03788Imported, ERS007741_02213Imported, ERS013471_02255Imported, ERS023446_03479Imported, ERS024276_00349Imported, ERS027646_01704Imported, ERS027659_00410Imported, ERS027661_01440Imported, ERS075361_02055Imported, ERS094182_02139Imported, F6W99_01429Imported, F9908_21175Imported, SAMEA2683035_02177Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMycobacterium tuberculosisImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1773 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000048948 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000256245 Componenti: Unassembled WGS sequence
  • UP000236349 Componenti: Chromosome
  • UP000297584 Componenti: Unassembled WGS sequence
  • UP000049989 Componenti: Unassembled WGS sequence
  • UP000041288 Componenti: Unassembled WGS sequence
  • UP000431688 Componenti: Unassembled WGS sequence
  • UP000043293 Componenti: Unassembled WGS sequence
  • UP000049023 Componenti: Unassembled WGS sequence
  • UP000048600 Componenti: Unassembled WGS sequence
  • UP000047893 Componenti: Unassembled WGS sequence
  • UP000039953 Componenti: Unassembled WGS sequence
  • UP000046947 Componenti: Unassembled WGS sequence
  • UP000182946 Componenti: Unassembled WGS sequence
  • UP000048289 Componenti: Unassembled WGS sequence
  • UP000046680 Componenti: Unassembled WGS sequence
  • UP000038802 Componenti: Unassembled WGS sequence
  • UP000042440 Componenti: Unassembled WGS sequence
  • UP000326088 Componenti: Chromosome
  • UP000046213 Componenti: Unassembled WGS sequence
  • UP000050164 Componenti: Unassembled WGS sequence
  • UP000040993 Componenti: Unassembled WGS sequence
  • UP000044938 Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CRISPR-associated Csm3 family.ARBA annotation

Family and domain databases

Conserved Domains Database

More...
CDDi
cd09684, Csm3_III-A, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013412, CRISPR-assoc_RAMP_Csm3
IPR005537, RAMP_III_fam

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03787, RAMPs, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR02582, cas7_TM1809, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A045JG98-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTTSYAKIEI TGTLTVLTGL QIGAGDGFSA IGAVDKPVVR DPLSRLPMIP
60 70 80 90 100
GTSLKGKVRT LLSRQYGADT ETFYRKPNED HAHIRRLFGD TEEYMTGRLV
110 120 130 140 150
FRDTKLTNKD DLEARGAKTL TEVKFENAIN RVTAKANLRQ MERVIPGSEF
160 170 180 190 200
AFSLVYEVSF GTPGEEQKAS LPSSDEIIED FNAIARGLKL LELDYLGGSG
210 220 230
TRGYGQVKFS NLKARAAVGA LDGSLLEKLN HELAAV
Length:236
Mass (Da):25,773
Last modified:July 9, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1728D20400321017
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP024614 Genomic DNA Translation: AUS51983.1
CFOE01000141 Genomic DNA Translation: CFE39034.1
CFOH01000173 Genomic DNA Translation: CFE49217.1
CGCX01000783 Genomic DNA Translation: CFR83403.1
CNCN01000046 Genomic DNA Translation: CKN75976.1
CNFT01000053 Genomic DNA Translation: CKQ93803.1
CNFU01000239 Genomic DNA Translation: CKR48548.1
CNGE01000268 Genomic DNA Translation: CKS35434.1
CQAC01000013 Genomic DNA Translation: CNG73211.1
CQGE01000112 Genomic DNA Translation: CNN44607.1
CQPL01000030 Genomic DNA Translation: CNT81536.1
CQPV01000470 Genomic DNA Translation: CNV27766.1
CQTT01000061 Genomic DNA Translation: CNY65319.1
CSAE01000074 Genomic DNA Translation: COV27009.1
CSAJ01000286 Genomic DNA Translation: COW30710.1
CHKL01000238 Genomic DNA Translation: COW33164.1
CSAM01000432 Genomic DNA Translation: COW94523.1
CVKR01000014 Genomic DNA Translation: CRF26698.1
WFKV01000047 Genomic DNA Translation: KAB7796982.1
CP044345 Genomic DNA Translation: QEX90642.1
QSXJ01001076 Genomic DNA Translation: REM61461.1
FPTZ01000013 Genomic DNA Translation: SGH85312.1
SRLJ01000051 Genomic DNA Translation: TGD71252.1

NCBI Reference Sequences

More...
RefSeqi
WP_003414292.1, NZ_WUJD01000041.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AMC47275; AMC47275; RN05_2999
CFE39034; CFE39034; ERS007681_01405
CFE49217; CFE49217; ERS007688_01385
CFR83403; CFR83403; ERS007657_02155
CKN75976; CKN75976; ERS024276_00349
CKQ92049; CKQ92049; ERS027654_00313
CKQ93803; CKQ93803; ERS027659_00410
CKR01868; CKR01868; ERS027656_00430
CKR09289; CKR09289; ERS027652_00676
CKR15976; CKR15976; ERS027653_00764
CKR48548; CKR48548; ERS027661_01440
CKR55920; CKR55920; ERS027644_01558
CKS35434; CKS35434; ERS027646_01704
CNH65926; CNH65926; ERS124361_04139
CNN44607; CNN44607; ERS023446_03479
CNT81536; CNT81536; ERS007670_00254
CNV27766; CNV27766; ERS007663_02787
CNY65319; CNY65319; ERS013471_02255
COU65800; COU65800; ERS007672_00119
COV27009; COV27009; ERS007703_00997
COW30710; COW30710; ERS007720_02303
COW33164; COW33164; ERS007741_02213
COW94523; COW94523; ERS007722_03788
CRH11116; CRH11116; BN1303_00929
CRH15558; CRH15558; BN1213_03392

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
23490943

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1773.206.peg.1603

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP024614 Genomic DNA Translation: AUS51983.1
CFOE01000141 Genomic DNA Translation: CFE39034.1
CFOH01000173 Genomic DNA Translation: CFE49217.1
CGCX01000783 Genomic DNA Translation: CFR83403.1
CNCN01000046 Genomic DNA Translation: CKN75976.1
CNFT01000053 Genomic DNA Translation: CKQ93803.1
CNFU01000239 Genomic DNA Translation: CKR48548.1
CNGE01000268 Genomic DNA Translation: CKS35434.1
CQAC01000013 Genomic DNA Translation: CNG73211.1
CQGE01000112 Genomic DNA Translation: CNN44607.1
CQPL01000030 Genomic DNA Translation: CNT81536.1
CQPV01000470 Genomic DNA Translation: CNV27766.1
CQTT01000061 Genomic DNA Translation: CNY65319.1
CSAE01000074 Genomic DNA Translation: COV27009.1
CSAJ01000286 Genomic DNA Translation: COW30710.1
CHKL01000238 Genomic DNA Translation: COW33164.1
CSAM01000432 Genomic DNA Translation: COW94523.1
CVKR01000014 Genomic DNA Translation: CRF26698.1
WFKV01000047 Genomic DNA Translation: KAB7796982.1
CP044345 Genomic DNA Translation: QEX90642.1
QSXJ01001076 Genomic DNA Translation: REM61461.1
FPTZ01000013 Genomic DNA Translation: SGH85312.1
SRLJ01000051 Genomic DNA Translation: TGD71252.1
RefSeqiWP_003414292.1, NZ_WUJD01000041.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiAMC47275; AMC47275; RN05_2999
CFE39034; CFE39034; ERS007681_01405
CFE49217; CFE49217; ERS007688_01385
CFR83403; CFR83403; ERS007657_02155
CKN75976; CKN75976; ERS024276_00349
CKQ92049; CKQ92049; ERS027654_00313
CKQ93803; CKQ93803; ERS027659_00410
CKR01868; CKR01868; ERS027656_00430
CKR09289; CKR09289; ERS027652_00676
CKR15976; CKR15976; ERS027653_00764
CKR48548; CKR48548; ERS027661_01440
CKR55920; CKR55920; ERS027644_01558
CKS35434; CKS35434; ERS027646_01704
CNH65926; CNH65926; ERS124361_04139
CNN44607; CNN44607; ERS023446_03479
CNT81536; CNT81536; ERS007670_00254
CNV27766; CNV27766; ERS007663_02787
CNY65319; CNY65319; ERS013471_02255
COU65800; COU65800; ERS007672_00119
COV27009; COV27009; ERS007703_00997
COW30710; COW30710; ERS007720_02303
COW33164; COW33164; ERS007741_02213
COW94523; COW94523; ERS007722_03788
CRH11116; CRH11116; BN1303_00929
CRH15558; CRH15558; BN1213_03392
GeneIDi23490943
PATRICifig|1773.206.peg.1603

Family and domain databases

CDDicd09684, Csm3_III-A, 1 hit
InterProiView protein in InterPro
IPR013412, CRISPR-assoc_RAMP_Csm3
IPR005537, RAMP_III_fam
PfamiView protein in Pfam
PF03787, RAMPs, 1 hit
TIGRFAMsiTIGR02582, cas7_TM1809, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A045JG98_MYCTX
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A045JG98
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: August 12, 2020
This is version 62 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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