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Entry version 59 (17 Jun 2020)
Sequence version 1 (09 Jul 2014)
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Protein
Submitted name:

Hypothetical alanine and glycine rich protein

Gene

espB

Organism
Mycobacterium tuberculosis
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Hypothetical alanine and glycine rich proteinImported
Submitted name:
Type VII secretion system ESX-1 target EspBImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:espBImported
ORF Names:AYJ03_020505Imported, ERS007679_01724Imported, ERS007741_02902Imported, ERS013471_03403Imported, ERS023446_03491Imported, ERS027659_00836Imported, ERS075361_00389Imported, ERS094182_00723Imported, GJE03_20410Imported, SAMEA2683035_00091Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMycobacterium tuberculosisImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1773 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000048600 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000047893 Componenti: Unassembled WGS sequence
  • UP000039953 Componenti: Unassembled WGS sequence
  • UP000182946 Componenti: Unassembled WGS sequence
  • UP000075723 Componenti: Chromosome
  • UP000042440 Componenti: Unassembled WGS sequence
  • UP000045842 Componenti: Unassembled WGS sequence
  • UP000388593 Componenti: Chromosome
  • UP000050164 Componenti: Unassembled WGS sequence
  • UP000040993 Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini12 – 88EspB_PEInterPro annotationAdd BLAST77

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni92 – 116DisorderedSequence analysisAdd BLAST25
Regioni303 – 335DisorderedSequence analysisAdd BLAST33
Regioni405 – 441DisorderedSequence analysisAdd BLAST37

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR041275 EspB_PE

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF18625 EspB_PE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A045ILP6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTQSQTVTVD QQEILNRANE VEAPMADPPT DVPITPCELT AAKNAAQQLV
60 70 80 90 100
LSADNMREYL AAGAKERQRL ATSLRNAAKA YGEVDEEAAT ALDNDGEGTV
110 120 130 140 150
QAESAGAVGG DSSAELTDTP RVATAGEPNF MDLKEAARKL ETGDQGASLA
160 170 180 190 200
HFADGWNTFN LTLQGDVKRF RGFDNWEGDA ATACEASLDQ QRQWILHMAK
210 220 230 240 250
LSAAMAKQAQ YVAQLHVWAR REHPTYEDIV GLERLYAENP SARDQILPVY
260 270 280 290 300
AEYQQRSEKV LTEYNNKAAL EPVNPPKPPP AIKIDPPPPP QEQGLIPGFL
310 320 330 340 350
MPPSDGSGVT PGTGMPAAPM VPPTGSPGGG LPADTAAQLT SAGREAAALS
360 370 380 390 400
GDVAVKAASL GGGGGGGVPS APLGSAIGGA ESVRPAGAGD IAGLGQGRAG
410 420 430 440 450
GGAALGGGGM GMPMGAAHQG QGGAKSKGSQ QEDEALYTED RAWTEAVIGN
460
RRRQDSKESK
Length:460
Mass (Da):47,594
Last modified:July 9, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7528743226AD7A71
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CNFT01000128 Genomic DNA Translation: CKR16583.1
CQAC01000002 Genomic DNA Translation: CNG07244.1
CQGE01000113 Genomic DNA Translation: CNN44928.1
CQTT01000131 Genomic DNA Translation: CNZ04679.1
CSAD01000197 Genomic DNA Translation: COV37761.1
CHKL01000379 Genomic DNA Translation: COW66460.1
CVKR01000004 Genomic DNA Translation: CRF25305.1
CP045962 Genomic DNA Translation: QGK80935.1
CP046529 Genomic DNA Translation: QGV23421.1
FPTZ01000001 Genomic DNA Translation: SGH01434.1

NCBI Reference Sequences

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RefSeqi
WP_003399995.1, NZ_WFLD01000023.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AMC48411; AMC48411; RN05_4135
CKR16583; CKR16583; ERS027659_00836
CKR17625; CKR17625; ERS027652_00841
CNG78942; CNG78942; ERS124361_01886
CNN44928; CNN44928; ERS023446_03491
CNZ04679; CNZ04679; ERS013471_03403
COV37254; COV37254; ERS007672_01679
COV37761; COV37761; ERS007679_01724
COW66460; COW66460; ERS007741_02902
CRH14860; CRH14860; BN1303_02868

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1773.206.peg.263

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CNFT01000128 Genomic DNA Translation: CKR16583.1
CQAC01000002 Genomic DNA Translation: CNG07244.1
CQGE01000113 Genomic DNA Translation: CNN44928.1
CQTT01000131 Genomic DNA Translation: CNZ04679.1
CSAD01000197 Genomic DNA Translation: COV37761.1
CHKL01000379 Genomic DNA Translation: COW66460.1
CVKR01000004 Genomic DNA Translation: CRF25305.1
CP045962 Genomic DNA Translation: QGK80935.1
CP046529 Genomic DNA Translation: QGV23421.1
FPTZ01000001 Genomic DNA Translation: SGH01434.1
RefSeqiWP_003399995.1, NZ_WFLD01000023.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiAMC48411; AMC48411; RN05_4135
CKR16583; CKR16583; ERS027659_00836
CKR17625; CKR17625; ERS027652_00841
CNG78942; CNG78942; ERS124361_01886
CNN44928; CNN44928; ERS023446_03491
CNZ04679; CNZ04679; ERS013471_03403
COV37254; COV37254; ERS007672_01679
COV37761; COV37761; ERS007679_01724
COW66460; COW66460; ERS007741_02902
CRH14860; CRH14860; BN1303_02868
PATRICifig|1773.206.peg.263

Family and domain databases

InterProiView protein in InterPro
IPR041275 EspB_PE
PfamiView protein in Pfam
PF18625 EspB_PE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A045ILP6_MYCTX
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A045ILP6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: June 17, 2020
This is version 59 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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