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Entry version 59 (11 Dec 2019)
Sequence version 1 (09 Jul 2014)
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Protein

Phosphate-specific transport system accessory protein PhoU

Gene

phoU

Organism
Mycobacterium tuberculosis
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in the regulation of phosphate uptake.UniRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processPhosphate transportUniRule annotation, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Phosphate-specific transport system accessory protein PhoUUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:phoUImported
Synonyms:phoY1Imported
ORF Names:CAB90_03713Imported, ERS007703_02416Imported, ERS023446_02185Imported, ERS027651_00757Imported, EZX46_12065Imported, FDK60_16655Imported, FDK62_13100Imported, SAMEA2682864_02379Imported, SAMEA2683035_02834Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMycobacterium tuberculosisImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1773 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000183655 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000306581 Componenti: Unassembled WGS sequence
  • UP000298273 Componenti: Unassembled WGS sequence
  • UP000039953 Componenti: Unassembled WGS sequence
  • UP000305204 Componenti: Unassembled WGS sequence
  • UP000182946 Componenti: Unassembled WGS sequence
  • UP000236349 Componenti: Chromosome
  • UP000038802 Componenti: Unassembled WGS sequence
  • UP000049058 Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

UniRule annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini17 – 104PhoUInterPro annotationAdd BLAST88
Domaini123 – 204PhoUInterPro annotationAdd BLAST82

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PhoU family.UniRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG0704 LUCA

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.58.220, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR028366 P_transport_PhoU
IPR038078 PhoU-like_sf
IPR026022 PhoU_dom

The PANTHER Classification System

More...
PANTHERi
PTHR42930:SF3 PTHR42930:SF3, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01895 PhoU, 2 hits

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF003107 PhoU, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR02135 phoU_full, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A045IA85-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRTVYHQRLT ELAGRLGEMC SLAGIAMKRA TQALLEADIG AAEQVIRDHE
60 70 80 90 100
RIVAMRAQVE KEAFALLALQ HPVAGELREI FSAVQIIADT ERMGALAVHI
110 120 130 140 150
AKITRREYPN QVLPEEVRNC FADMAKVAIA LGDSARQVLV NRDPQEAAQL
160 170 180 190 200
HDRDDAMDDL HRHLLSVLID REWRHGVRVG VETALLGRFF ERFADHAVEV
210 220
GRRVIFMVTG VLPTEDEIST Y
Length:221
Mass (Da):24,827
Last modified:July 9, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i94CEAA23E31BCD32
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP024614 Genomic DNA Translation: AUS52525.1
CIEA01000005 Genomic DNA Translation: CKR57377.1
CQGE01000045 Genomic DNA Translation: CNN11092.1
CSAE01000261 Genomic DNA Translation: COV96909.1
FPTZ01000021 Genomic DNA Translation: SGI10051.1
FPXX01000014 Genomic DNA Translation: SGM43085.1
SMOE01000092 Genomic DNA Translation: TFB21969.1
SZTS01000063 Genomic DNA Translation: TKR37856.1
SZTU01000055 Genomic DNA Translation: TKR50999.1

NCBI Reference Sequences

More...
RefSeqi
WP_003417216.1, NZ_VOVY01000007.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AMC47782; AMC47782; RN05_3506
CFE39384; CFE39384; ERS007681_01764
CFE58811; CFE58811; ERS007688_02732
CFR88055; CFR88055; ERS007657_02647
CKO44494; CKO44494; ERS024213_00467
CKR87739; CKR87739; ERS027654_02390
CKS00025; CKS00025; ERS027661_02447
CKS34575; CKS34575; ERS027659_02973
CKS95953; CKS95953; ERS027644_03718
CKT02445; CKT02445; ERS027652_03960
CKT19282; CKT19282; ERS027656_04031
CKT39938; CKT39938; ERS027646_03490
CKU49947; CKU49947; ERS027666_04295
CKW09977; CKW09977; ERS031537_03768
CNH32226; CNH32226; ERS124361_03391
CNN11092; CNN11092; ERS023446_02185
CNU25501; CNU25501; ERS007663_00830
CNU33741; CNU33741; ERS007670_01320
CNV42013; CNV42013; ERS007661_02332
CNV49588; CNV49588; ERS007665_03134
CNY50621; CNY50621; ERS013471_01798
COU84122; COU84122; ERS007672_00486
COV40502; COV40502; ERS007679_01778
COV96909; COV96909; ERS007703_02416
COV98049; COV98049; ERS007722_01285
COW29144; COW29144; ERS007741_02092
COX70470; COX70470; ERS007720_04813
COX83500; COX83500; ERS007739_01780
COX92947; COX92947; ERS007731_02609
CRH11758; CRH11758; BN1213_01414
CRH16354; CRH16354; BN1303_03636

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1773.206.peg.3679

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP024614 Genomic DNA Translation: AUS52525.1
CIEA01000005 Genomic DNA Translation: CKR57377.1
CQGE01000045 Genomic DNA Translation: CNN11092.1
CSAE01000261 Genomic DNA Translation: COV96909.1
FPTZ01000021 Genomic DNA Translation: SGI10051.1
FPXX01000014 Genomic DNA Translation: SGM43085.1
SMOE01000092 Genomic DNA Translation: TFB21969.1
SZTS01000063 Genomic DNA Translation: TKR37856.1
SZTU01000055 Genomic DNA Translation: TKR50999.1
RefSeqiWP_003417216.1, NZ_VOVY01000007.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiAMC47782; AMC47782; RN05_3506
CFE39384; CFE39384; ERS007681_01764
CFE58811; CFE58811; ERS007688_02732
CFR88055; CFR88055; ERS007657_02647
CKO44494; CKO44494; ERS024213_00467
CKR87739; CKR87739; ERS027654_02390
CKS00025; CKS00025; ERS027661_02447
CKS34575; CKS34575; ERS027659_02973
CKS95953; CKS95953; ERS027644_03718
CKT02445; CKT02445; ERS027652_03960
CKT19282; CKT19282; ERS027656_04031
CKT39938; CKT39938; ERS027646_03490
CKU49947; CKU49947; ERS027666_04295
CKW09977; CKW09977; ERS031537_03768
CNH32226; CNH32226; ERS124361_03391
CNN11092; CNN11092; ERS023446_02185
CNU25501; CNU25501; ERS007663_00830
CNU33741; CNU33741; ERS007670_01320
CNV42013; CNV42013; ERS007661_02332
CNV49588; CNV49588; ERS007665_03134
CNY50621; CNY50621; ERS013471_01798
COU84122; COU84122; ERS007672_00486
COV40502; COV40502; ERS007679_01778
COV96909; COV96909; ERS007703_02416
COV98049; COV98049; ERS007722_01285
COW29144; COW29144; ERS007741_02092
COX70470; COX70470; ERS007720_04813
COX83500; COX83500; ERS007739_01780
COX92947; COX92947; ERS007731_02609
CRH11758; CRH11758; BN1213_01414
CRH16354; CRH16354; BN1303_03636
PATRICifig|1773.206.peg.3679

Phylogenomic databases

eggNOGiCOG0704 LUCA

Family and domain databases

Gene3Di1.20.58.220, 1 hit
InterProiView protein in InterPro
IPR028366 P_transport_PhoU
IPR038078 PhoU-like_sf
IPR026022 PhoU_dom
PANTHERiPTHR42930:SF3 PTHR42930:SF3, 1 hit
PfamiView protein in Pfam
PF01895 PhoU, 2 hits
PIRSFiPIRSF003107 PhoU, 1 hit
TIGRFAMsiTIGR02135 phoU_full, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A045IA85_MYCTX
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A045IA85
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: December 11, 2019
This is version 59 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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